FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4292289544> ?p ?o ?g. }

• W4292289544 abstract "Abstract Previous studies have explored the associations of retinal vessel calibre, measured from retinal photographs or fundus images using semi-automated computer programs, with cognitive impairment and dementia, supporting the concept that retinal blood vessels reflect microvascular changes in the brain. Recently, artificial intelligence deep-learning algorithms have been developed for the fully automated assessment of retinal vessel calibres. Therefore, we aimed to determine whether deep-learning-based retinal vessel calibre measurements are predictive of risk of cognitive decline and dementia. We conducted a prospective study recruiting participants from memory clinics at the National University Hospital and St. Luke’s Hospital in Singapore; all participants had comprehensive clinical and neuropsychological examinations at baseline and annually for up to 5 years. Fully automated measurements of retinal arteriolar and venular calibres from retinal fundus images were estimated using a deep-learning system. Cox regression models were then used to assess the relationship between baseline retinal vessel calibre and the risk of cognitive decline and developing dementia, adjusting for age, gender, ethnicity, education, cerebrovascular disease status, hypertension, hyperlipidemia, diabetes, and smoking. A total of 491 participants were included in this study, of whom 254 developed cognitive decline over 5 years. In multivariable models, narrower retinal arteriolar calibre (hazard ratio per standard deviation decrease = 1.258, P = 0.008) and wider retinal venular calibre (hazard ratio per standard deviation increase = 1.204, P = 0.037) were associated with increased risk of cognitive decline. Among participants with cognitive impairment but no dementia at baseline (n = 212), 44 progressed to have incident dementia; narrower retinal arteriolar calibre was also associated with incident dementia (hazard ratio per standard deviation decrease = 1.624, P = 0.021). In summary, deep-learning-based measurement of retinal vessel calibre was associated with risk of cognitive decline and dementia." @default.
• W4292289544 created "2022-08-19" @default.
• W4292289544 creator A5008989080 @default.
• W4292289544 creator A5010947615 @default.
• W4292289544 creator A5015017045 @default.
• W4292289544 creator A5019441816 @default.
• W4292289544 creator A5019493583 @default.
• W4292289544 creator A5019988958 @default.
• W4292289544 creator A5022789521 @default.
• W4292289544 creator A5025800318 @default.
• W4292289544 creator A5040482050 @default.
• W4292289544 creator A5050763071 @default.
• W4292289544 creator A5051209739 @default.
• W4292289544 creator A5063016255 @default.
• W4292289544 creator A5072258594 @default.
• W4292289544 creator A5085096438 @default.
• W4292289544 date "2022-07-04" @default.
• W4292289544 modified "2023-10-18" @default.
• W4292289544 title "Deep-learning retinal vessel calibre measurements and risk of cognitive decline and dementia" @default.
• W4292289544 cites W1567524252 @default.
• W4292289544 cites W1600134865 @default.
• W4292289544 cites W1965801493 @default.
• W4292289544 cites W1967528449 @default.
• W4292289544 cites W1968934139 @default.
• W4292289544 cites W1971086948 @default.
• W4292289544 cites W1974803357 @default.
• W4292289544 cites W1975605692 @default.
• W4292289544 cites W1982145607 @default.
• W4292289544 cites W1991934654 @default.
• W4292289544 cites W1992300263 @default.
• W4292289544 cites W1998046077 @default.
• W4292289544 cites W2004217515 @default.
• W4292289544 cites W2007688696 @default.
• W4292289544 cites W2008752697 @default.
• W4292289544 cites W2014447462 @default.
• W4292289544 cites W2027988022 @default.
• W4292289544 cites W2034888646 @default.
• W4292289544 cites W2037477786 @default.
• W4292289544 cites W2040312483 @default.
• W4292289544 cites W2040982608 @default.
• W4292289544 cites W2058239891 @default.
• W4292289544 cites W2072684660 @default.
• W4292289544 cites W2087599099 @default.
• W4292289544 cites W2090496521 @default.
• W4292289544 cites W2101216584 @default.
• W4292289544 cites W2104801393 @default.
• W4292289544 cites W2105790910 @default.
• W4292289544 cites W2108474398 @default.
• W4292289544 cites W2113082716 @default.
• W4292289544 cites W2126084914 @default.
• W4292289544 cites W2129698390 @default.
• W4292289544 cites W2130199346 @default.
• W4292289544 cites W2144220340 @default.
• W4292289544 cites W2146610322 @default.
• W4292289544 cites W2298913877 @default.
• W4292289544 cites W2328932654 @default.
• W4292289544 cites W2410623364 @default.
• W4292289544 cites W2468582030 @default.
• W4292289544 cites W2560016272 @default.
• W4292289544 cites W2570247064 @default.
• W4292289544 cites W2587624076 @default.
• W4292289544 cites W2735069571 @default.
• W4292289544 cites W2772246530 @default.
• W4292289544 cites W2786619296 @default.
• W4292289544 cites W2791488094 @default.
• W4292289544 cites W2791710398 @default.
• W4292289544 cites W2885490951 @default.
• W4292289544 cites W2904519691 @default.
• W4292289544 cites W2923715522 @default.
• W4292289544 cites W2936956353 @default.
• W4292289544 cites W2952072456 @default.
• W4292289544 cites W2964291324 @default.
• W4292289544 cites W2974726644 @default.
• W4292289544 cites W2991209955 @default.
• W4292289544 cites W3091908957 @default.
• W4292289544 cites W3167429032 @default.
• W4292289544 cites W4247665917 @default.
• W4292289544 cites W4361024659 @default.
• W4292289544 cites W4380208384 @default.
• W4292289544 doi "https://doi.org/10.1093/braincomms/fcac212" @default.
• W4292289544 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36043139" @default.
• W4292289544 hasPublicationYear "2022" @default.
• W4292289544 type Work @default.
• W4292289544 citedByCount "6" @default.
• W4292289544 countsByYear W42922895442023 @default.
• W4292289544 crossrefType "journal-article" @default.
• W4292289544 hasAuthorship W4292289544A5008989080 @default.
• W4292289544 hasAuthorship W4292289544A5010947615 @default.
• W4292289544 hasAuthorship W4292289544A5015017045 @default.
• W4292289544 hasAuthorship W4292289544A5019441816 @default.
• W4292289544 hasAuthorship W4292289544A5019493583 @default.
• W4292289544 hasAuthorship W4292289544A5019988958 @default.
• W4292289544 hasAuthorship W4292289544A5022789521 @default.
• W4292289544 hasAuthorship W4292289544A5025800318 @default.
• W4292289544 hasAuthorship W4292289544A5040482050 @default.
• W4292289544 hasAuthorship W4292289544A5050763071 @default.
• W4292289544 hasAuthorship W4292289544A5051209739 @default.
• W4292289544 hasAuthorship W4292289544A5063016255 @default.
• W4292289544 hasAuthorship W4292289544A5072258594 @default.
• W4292289544 hasAuthorship W4292289544A5085096438 @default.

• next