FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4292371830> ?p ?o ?g. }

• W4292371830 endingPage "1749" @default.
• W4292371830 startingPage "1739" @default.
• W4292371830 abstract "Friedreich ataxia (FA) is a rare, inherited neuromuscular disease characterized by an early onset and progressive limb and gait ataxia. Currently, there are no approved treatments for FA. It is important to understand the burden of FA, including its extent and the most salient elements. The objective of this study is therefore to systematically review the literature regarding the aspects of prevalence, health-related quality of life (HRQoL), and economic outcomes that are associated with FA, and to subsequently identify relevant knowledge gaps.Three systematic literature reviews were conducted to assess publications regarding FA prevalence, HRQoL, and economic outcomes. Search strategies were implemented in MEDLINE (Ovid) and EMBASE databases; study selection and quality assessment were conducted using current best practices. For each review, study characteristics and findings were summarized.A total of 36 studies were included. Review of prevalence studies (n = 22) indicated variation in the number of cases by region, and many regions were not represented at all. Regarding HRQoL (n = 12 studies), physical domains were consistently impacted, although findings regarding other domains and overall HRQoL were less clear. Cost studies (n = 2) encompassed 4 regions and revealed that costs related to the provision of care, including non-medical direct costs and indirect costs, accounted for the majority of FA-related costs.Findings from this systematic review revealed several knowledge gaps that would preclude the conduct of a robust assessment of the benefits and outcomes associated with a disease-modifying FA therapy. Additional understanding regarding patient and caregiver HRQoL and costs is required." @default.
• W4292371830 created "2022-08-20" @default.
• W4292371830 creator A5053209536 @default.
• W4292371830 creator A5083367204 @default.
• W4292371830 date "2022-08-23" @default.
• W4292371830 modified "2023-09-25" @default.
• W4292371830 title "A systematic review of disease prevalence, health-related quality of life, and economic outcomes associated with Friedreich’s Ataxia" @default.
• W4292371830 cites W1971616671 @default.
• W4292371830 cites W1971998465 @default.
• W4292371830 cites W1972998684 @default.
• W4292371830 cites W1985093325 @default.
• W4292371830 cites W1994903929 @default.
• W4292371830 cites W1995962173 @default.
• W4292371830 cites W1999432313 @default.
• W4292371830 cites W2001335034 @default.
• W4292371830 cites W2006671194 @default.
• W4292371830 cites W2013188809 @default.
• W4292371830 cites W2015538209 @default.
• W4292371830 cites W2025833673 @default.
• W4292371830 cites W2032743433 @default.
• W4292371830 cites W2041213023 @default.
• W4292371830 cites W2042953568 @default.
• W4292371830 cites W2043988399 @default.
• W4292371830 cites W2062687911 @default.
• W4292371830 cites W2066714193 @default.
• W4292371830 cites W2076116011 @default.
• W4292371830 cites W2089449685 @default.
• W4292371830 cites W2089694779 @default.
• W4292371830 cites W2098829088 @default.
• W4292371830 cites W2102559235 @default.
• W4292371830 cites W2106020848 @default.
• W4292371830 cites W2107849284 @default.
• W4292371830 cites W2112233641 @default.
• W4292371830 cites W2151362789 @default.
• W4292371830 cites W2155599513 @default.
• W4292371830 cites W2158155007 @default.
• W4292371830 cites W2158985108 @default.
• W4292371830 cites W2163905230 @default.
• W4292371830 cites W2167527362 @default.
• W4292371830 cites W2313668280 @default.
• W4292371830 cites W2336904126 @default.
• W4292371830 cites W2525309459 @default.
• W4292371830 cites W2552065052 @default.
• W4292371830 cites W2567362164 @default.
• W4292371830 cites W2605279931 @default.
• W4292371830 cites W2765363512 @default.
• W4292371830 cites W2796348532 @default.
• W4292371830 cites W2809732559 @default.
• W4292371830 cites W2890080732 @default.
• W4292371830 cites W2973267506 @default.
• W4292371830 cites W2976049852 @default.
• W4292371830 cites W2998689656 @default.
• W4292371830 cites W4205334506 @default.
• W4292371830 cites W4211173369 @default.
• W4292371830 cites W4294215472 @default.
• W4292371830 doi "https://doi.org/10.1080/03007995.2022.2112870" @default.
• W4292371830 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35983717" @default.
• W4292371830 hasPublicationYear "2022" @default.
• W4292371830 type Work @default.
• W4292371830 citedByCount "1" @default.
• W4292371830 countsByYear W42923718302023 @default.
• W4292371830 crossrefType "journal-article" @default.
• W4292371830 hasAuthorship W4292371830A5053209536 @default.
• W4292371830 hasAuthorship W4292371830A5083367204 @default.
• W4292371830 hasConcept C118552586 @default.
• W4292371830 hasConcept C142724271 @default.
• W4292371830 hasConcept C159110408 @default.
• W4292371830 hasConcept C160735492 @default.
• W4292371830 hasConcept C162324750 @default.
• W4292371830 hasConcept C17744445 @default.
• W4292371830 hasConcept C1862650 @default.
• W4292371830 hasConcept C189708586 @default.
• W4292371830 hasConcept C199539241 @default.
• W4292371830 hasConcept C2779134260 @default.
• W4292371830 hasConcept C2779473830 @default.
• W4292371830 hasConcept C2779951463 @default.
• W4292371830 hasConcept C2780906641 @default.
• W4292371830 hasConcept C50522688 @default.
• W4292371830 hasConcept C71924100 @default.
• W4292371830 hasConcept C74909509 @default.
• W4292371830 hasConceptScore W4292371830C118552586 @default.
• W4292371830 hasConceptScore W4292371830C142724271 @default.
• W4292371830 hasConceptScore W4292371830C159110408 @default.
• W4292371830 hasConceptScore W4292371830C160735492 @default.
• W4292371830 hasConceptScore W4292371830C162324750 @default.
• W4292371830 hasConceptScore W4292371830C17744445 @default.
• W4292371830 hasConceptScore W4292371830C1862650 @default.
• W4292371830 hasConceptScore W4292371830C189708586 @default.
• W4292371830 hasConceptScore W4292371830C199539241 @default.
• W4292371830 hasConceptScore W4292371830C2779134260 @default.
• W4292371830 hasConceptScore W4292371830C2779473830 @default.
• W4292371830 hasConceptScore W4292371830C2779951463 @default.
• W4292371830 hasConceptScore W4292371830C2780906641 @default.
• W4292371830 hasConceptScore W4292371830C50522688 @default.
• W4292371830 hasConceptScore W4292371830C71924100 @default.
• W4292371830 hasConceptScore W4292371830C74909509 @default.
• W4292371830 hasFunder F4320314126 @default.
• W4292371830 hasIssue "10" @default.

• next