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- W4292451787 abstract "To date, the involvement of α-Lactalbumin (α-LA) in the management of polycystic ovary syndrome (PCOS) refers to its ability to improve intestinal absorption of natural molecules like inositols, overcoming the inositol resistance. However, due to its own aminoacidic building blocks, α-LA is involved in various biological processes that can open new additional applications. A great portion of women with PCOS exhibit gastrointestinal dysbiosis, which is in turn one of the triggering mechanisms of the syndrome. Due to its prebiotic effect, α-LA can recover dysbiosis, also improving the insulin resistance, obesity and intestinal inflammation frequently associated with PCOS. Further observations suggest that altered gut microbiota negatively influence mental wellbeing. Depressive mood and low serotonin levels are indeed common features of women with PCOS. Thanks to its content of tryptophan, which is the precursor of serotonin, and considering the strict link between gut and brain, using α-LA contributes to preserving mental well-being by maintaining high levels of serotonin. In addition, considering women with PCOS seeking pregnancy, both altered microbiota and serotonin levels can induce later consequences in the offspring. Therefore, a deeper knowledge of potential applications of α-LA is required to transition to preclinical and clinical studies extending its therapeutic advantages in PCOS." @default.
- W4292451787 created "2022-08-20" @default.
- W4292451787 creator A5008840195 @default.
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- W4292451787 date "2022-08-06" @default.
- W4292451787 modified "2023-09-28" @default.
- W4292451787 title "Positive Effects of α-Lactalbumin in the Management of Symptoms of Polycystic Ovary Syndrome" @default.
- W4292451787 cites W1046142428 @default.
- W4292451787 cites W1499197499 @default.
- W4292451787 cites W1924157033 @default.
- W4292451787 cites W1932402193 @default.
- W4292451787 cites W1942982649 @default.
- W4292451787 cites W1943352132 @default.
- W4292451787 cites W1965422885 @default.
- W4292451787 cites W1981665764 @default.
- W4292451787 cites W1993538553 @default.
- W4292451787 cites W1993553086 @default.
- W4292451787 cites W2000058430 @default.
- W4292451787 cites W2001111622 @default.
- W4292451787 cites W2002238780 @default.
- W4292451787 cites W2007411096 @default.
- W4292451787 cites W2008042293 @default.
- W4292451787 cites W2012114811 @default.
- W4292451787 cites W2013371150 @default.
- W4292451787 cites W2014025975 @default.
- W4292451787 cites W2020478376 @default.
- W4292451787 cites W2023097548 @default.
- W4292451787 cites W2023506796 @default.
- W4292451787 cites W2036270888 @default.
- W4292451787 cites W2037606317 @default.
- W4292451787 cites W2038771513 @default.
- W4292451787 cites W2039207629 @default.
- W4292451787 cites W2043555322 @default.
- W4292451787 cites W2045283840 @default.
- W4292451787 cites W2049014963 @default.
- W4292451787 cites W2049138480 @default.
- W4292451787 cites W2059445871 @default.
- W4292451787 cites W2063700488 @default.
- W4292451787 cites W2064075204 @default.
- W4292451787 cites W2064633474 @default.
- W4292451787 cites W2067082722 @default.
- W4292451787 cites W2077046937 @default.
- W4292451787 cites W2084256952 @default.
- W4292451787 cites W2090760174 @default.
- W4292451787 cites W2099122207 @default.
- W4292451787 cites W2101689484 @default.
- W4292451787 cites W2112799616 @default.
- W4292451787 cites W2119611447 @default.
- W4292451787 cites W2120563211 @default.
- W4292451787 cites W2121753319 @default.
- W4292451787 cites W2123009569 @default.
- W4292451787 cites W2124476616 @default.
- W4292451787 cites W2125529814 @default.
- W4292451787 cites W2131536322 @default.
- W4292451787 cites W2153044667 @default.
- W4292451787 cites W2167511301 @default.
- W4292451787 cites W2186218348 @default.
- W4292451787 cites W2225512866 @default.
- W4292451787 cites W2339818293 @default.
- W4292451787 cites W2404939443 @default.
- W4292451787 cites W2409273775 @default.
- W4292451787 cites W2531320855 @default.
- W4292451787 cites W2545069822 @default.
- W4292451787 cites W2558318064 @default.
- W4292451787 cites W2583513713 @default.
- W4292451787 cites W2590245531 @default.
- W4292451787 cites W2592172277 @default.
- W4292451787 cites W2604323123 @default.
- W4292451787 cites W2616825195 @default.
- W4292451787 cites W2651468154 @default.
- W4292451787 cites W2735897007 @default.
- W4292451787 cites W2751534677 @default.
- W4292451787 cites W2765864497 @default.
- W4292451787 cites W2774506533 @default.
- W4292451787 cites W2778416039 @default.
- W4292451787 cites W2790782988 @default.
- W4292451787 cites W2791493679 @default.
- W4292451787 cites W2792000617 @default.
- W4292451787 cites W2792716492 @default.
- W4292451787 cites W2794548917 @default.
- W4292451787 cites W2799415441 @default.
- W4292451787 cites W2799658728 @default.
- W4292451787 cites W2799722465 @default.
- W4292451787 cites W2801262515 @default.
- W4292451787 cites W2802043479 @default.
- W4292451787 cites W2804088205 @default.
- W4292451787 cites W2804823645 @default.
- W4292451787 cites W2807451237 @default.
- W4292451787 cites W2807772034 @default.
- W4292451787 cites W2884536266 @default.
- W4292451787 cites W2884935659 @default.
- W4292451787 cites W2885369519 @default.
- W4292451787 cites W2894592937 @default.