Matches in SemOpenAlex for { <https://semopenalex.org/work/W4292505890> ?p ?o ?g. }
Showing items 1 to 76 of
76
with 100 items per page.
- W4292505890 abstract "Background: Hypertensive disorder of pregnancy (HDP), a common obstetric complication that seriously threatens maternal and infant health. The current clinical treatment drugs include methyldopa, calcium channel blockers, etc. In order to provide evidence-based medicine for the treatment and medication of gestational hypertension, this study compared the efficacy and safety of different drugs in the treatment of gestational hypertension through network meta-analysis. Methods: Search and select relevant articles in the published and unpublished available data from Controlled Trials, PsycINFO, CINAHL,, etc. To assess the efficacy and safety of HDP treatment, 4 primary outcomes [SBP, DBP, perinatal fetal deaths, and NICU cases] and 9 secondary outcomes were selected. Results: 50 articles with 8212 participants were included. Low molecular weight heparin (LMH), Labetalol + LMH and Labetalol + Methyldopa can reduce DBP, and Ambrisentan + Methyldopa can prevent the occurrence of severe hypertension. Methyldopa and Atenolol were associated with lower rates of preterm birth, and Nifedipine, Methyldopa as well as Labetalol reduced the incidence of placental abruption. Ambrisentan + Nifedipine, Methyldopa, Labetalol + Nimodipine, Labetalol + LMH, Labetalol and LMH significantly reduced the incidence of postpartum complications. Magnesium sulfate (SM) and SM+ LMH can prolong the mean gestational age, LMH and Kethyldopa can reduce perinatal fetal death. Conclusions: LMH, labetalol, Methyldopa, labetalol in combination with LMH, and labetalol in combination with Methyldopa have better efficacy and safety." @default.
- W4292505890 created "2022-08-21" @default.
- W4292505890 creator A5022059655 @default.
- W4292505890 creator A5024970317 @default.
- W4292505890 creator A5026720211 @default.
- W4292505890 creator A5028714968 @default.
- W4292505890 creator A5030878539 @default.
- W4292505890 creator A5038478517 @default.
- W4292505890 creator A5041031867 @default.
- W4292505890 creator A5052554656 @default.
- W4292505890 creator A5086931892 @default.
- W4292505890 date "2022-08-10" @default.
- W4292505890 modified "2023-09-27" @default.
- W4292505890 title "Comparative efficacy and safety of antihypertensive agents in preeclampsia and gestational hypertension uncontrolled and their long-term effects on offspring" @default.
- W4292505890 doi "https://doi.org/10.22541/au.166013645.57377692/v1" @default.
- W4292505890 hasPublicationYear "2022" @default.
- W4292505890 type Work @default.
- W4292505890 citedByCount "0" @default.
- W4292505890 crossrefType "posted-content" @default.
- W4292505890 hasAuthorship W4292505890A5022059655 @default.
- W4292505890 hasAuthorship W4292505890A5024970317 @default.
- W4292505890 hasAuthorship W4292505890A5026720211 @default.
- W4292505890 hasAuthorship W4292505890A5028714968 @default.
- W4292505890 hasAuthorship W4292505890A5030878539 @default.
- W4292505890 hasAuthorship W4292505890A5038478517 @default.
- W4292505890 hasAuthorship W4292505890A5041031867 @default.
- W4292505890 hasAuthorship W4292505890A5052554656 @default.
- W4292505890 hasAuthorship W4292505890A5086931892 @default.
- W4292505890 hasConcept C126322002 @default.
- W4292505890 hasConcept C131872663 @default.
- W4292505890 hasConcept C2776289377 @default.
- W4292505890 hasConcept C2776525901 @default.
- W4292505890 hasConcept C2777218350 @default.
- W4292505890 hasConcept C2777583542 @default.
- W4292505890 hasConcept C2777962398 @default.
- W4292505890 hasConcept C2779066535 @default.
- W4292505890 hasConcept C2779234561 @default.
- W4292505890 hasConcept C2780719066 @default.
- W4292505890 hasConcept C42219234 @default.
- W4292505890 hasConcept C519063684 @default.
- W4292505890 hasConcept C54355233 @default.
- W4292505890 hasConcept C71924100 @default.
- W4292505890 hasConcept C84393581 @default.
- W4292505890 hasConcept C86803240 @default.
- W4292505890 hasConceptScore W4292505890C126322002 @default.
- W4292505890 hasConceptScore W4292505890C131872663 @default.
- W4292505890 hasConceptScore W4292505890C2776289377 @default.
- W4292505890 hasConceptScore W4292505890C2776525901 @default.
- W4292505890 hasConceptScore W4292505890C2777218350 @default.
- W4292505890 hasConceptScore W4292505890C2777583542 @default.
- W4292505890 hasConceptScore W4292505890C2777962398 @default.
- W4292505890 hasConceptScore W4292505890C2779066535 @default.
- W4292505890 hasConceptScore W4292505890C2779234561 @default.
- W4292505890 hasConceptScore W4292505890C2780719066 @default.
- W4292505890 hasConceptScore W4292505890C42219234 @default.
- W4292505890 hasConceptScore W4292505890C519063684 @default.
- W4292505890 hasConceptScore W4292505890C54355233 @default.
- W4292505890 hasConceptScore W4292505890C71924100 @default.
- W4292505890 hasConceptScore W4292505890C84393581 @default.
- W4292505890 hasConceptScore W4292505890C86803240 @default.
- W4292505890 hasLocation W42925058901 @default.
- W4292505890 hasOpenAccess W4292505890 @default.
- W4292505890 hasPrimaryLocation W42925058901 @default.
- W4292505890 hasRelatedWork W1977425813 @default.
- W4292505890 hasRelatedWork W2001459455 @default.
- W4292505890 hasRelatedWork W2018405500 @default.
- W4292505890 hasRelatedWork W2340809121 @default.
- W4292505890 hasRelatedWork W2607933197 @default.
- W4292505890 hasRelatedWork W2614440626 @default.
- W4292505890 hasRelatedWork W3145970805 @default.
- W4292505890 hasRelatedWork W4224299929 @default.
- W4292505890 hasRelatedWork W4292505890 @default.
- W4292505890 hasRelatedWork W80848042 @default.
- W4292505890 isParatext "false" @default.
- W4292505890 isRetracted "false" @default.
- W4292505890 workType "article" @default.