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- W4292510131 abstract "C. elegans shows robust and reproducible behavioral responses to oxygen. Specifically, worms prefer O 2 levels of 5-10% and avoid too high or too low O 2 . Their O 2 preference is not fixed but shows plasticity depending on experience, context, or genetic background. We recently showed that this experience-dependent plasticity declines with age, providing a useful behavioral readout for studying the mechanisms of age-related decline of neural plasticity. Here, we describe a technique to visualize behavioral O 2 preference and its plasticity in C. elegans , by creating spatial gradients of [O 2 ] in a microfluidic polydimethylsiloxane (PDMS) chamber and recording the resulting spatial distribution of the animals." @default.
- W4292510131 created "2022-08-21" @default.
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- W4292510131 date "2022-01-01" @default.
- W4292510131 modified "2023-09-27" @default.
- W4292510131 title "Aerotaxis Assay in Caenorhabditis elegans to Study Behavioral Plasticity" @default.
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- W4292510131 doi "https://doi.org/10.21769/bioprotoc.4492" @default.
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