FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4292575168> ?p ?o ?g. }

• W4292575168 abstract "Abstract Polyethylenimine (PEI) is considered as the gold standard for evaluating non‐viral gene vectors due to its proton sponge effect and high transfection efficiency. However, its cytotoxicity limits its application. Rice bran polysaccharide (RBP) is rich in nature and beneficial for preparation of biodegradable biomaterials. In this work, three PEI modified RBP‐Fe complexes (PIP‐1, PIP‐2, and PIP‐3) were prepared based on RBP with different molecular weight ( M w ). Then the potential of PIP complexes for plasmid DNA (pDNA) delivery and the influence of M w was studied. PIP complexes showed better safety and higher gene transfection efficiency than PEI. PIP‐1 was prepared by RBP with lower M w and could formed PIP‐1/pDNA nanoparticle with lower particle size which exhibited higher gene transfection efficiency than other PIP complexes prepared by RBP with higher M w . The results indicate that the PIP/pDNA complex exhibits a multi‐pathway cellular uptake mechanism. Clathrin dependent and caveolin dependent endocytosis and macropinocytosis were involved in the cellular uptake process of PIP/pDNA complex. It is hoped that this study can provide useful enlightenment for the research and development of gene vector based on polysaccharide." @default.
• W4292575168 created "2022-08-22" @default.
• W4292575168 creator A5012162209 @default.
• W4292575168 creator A5038131690 @default.
• W4292575168 creator A5053660330 @default.
• W4292575168 creator A5058073627 @default.
• W4292575168 creator A5086428144 @default.
• W4292575168 date "2022-08-22" @default.
• W4292575168 modified "2023-09-27" @default.
• W4292575168 title "Effect of molecular weight of polysaccharide on efficient plasmid <scp>DNA</scp> delivery by <scp>polyethylenimine‐polysaccharide‐Fe</scp>(<scp>III</scp>) complexes" @default.
• W4292575168 cites W1858570370 @default.
• W4292575168 cites W1968866426 @default.
• W4292575168 cites W1975530828 @default.
• W4292575168 cites W1978486312 @default.
• W4292575168 cites W2000802897 @default.
• W4292575168 cites W2004496952 @default.
• W4292575168 cites W2006802096 @default.
• W4292575168 cites W2014693615 @default.
• W4292575168 cites W2021667666 @default.
• W4292575168 cites W2022233756 @default.
• W4292575168 cites W2034569655 @default.
• W4292575168 cites W2036727780 @default.
• W4292575168 cites W2051958360 @default.
• W4292575168 cites W2058716233 @default.
• W4292575168 cites W2064021479 @default.
• W4292575168 cites W2070832637 @default.
• W4292575168 cites W2079762390 @default.
• W4292575168 cites W2083584116 @default.
• W4292575168 cites W2094028683 @default.
• W4292575168 cites W2172242781 @default.
• W4292575168 cites W2313698134 @default.
• W4292575168 cites W2527474055 @default.
• W4292575168 cites W2578301606 @default.
• W4292575168 cites W2625255376 @default.
• W4292575168 cites W2754738099 @default.
• W4292575168 cites W2768640048 @default.
• W4292575168 cites W2792523566 @default.
• W4292575168 cites W2885230950 @default.
• W4292575168 cites W2889033267 @default.
• W4292575168 cites W2891193109 @default.
• W4292575168 cites W2960931384 @default.
• W4292575168 cites W2965014132 @default.
• W4292575168 cites W2985239820 @default.
• W4292575168 cites W2985775924 @default.
• W4292575168 cites W3023807960 @default.
• W4292575168 cites W3092126620 @default.
• W4292575168 cites W3095353222 @default.
• W4292575168 cites W3111331330 @default.
• W4292575168 doi "https://doi.org/10.1002/app.53047" @default.
• W4292575168 hasPublicationYear "2022" @default.
• W4292575168 type Work @default.
• W4292575168 citedByCount "1" @default.
• W4292575168 countsByYear W42925751682023 @default.
• W4292575168 crossrefType "journal-article" @default.
• W4292575168 hasAuthorship W4292575168A5012162209 @default.
• W4292575168 hasAuthorship W4292575168A5038131690 @default.
• W4292575168 hasAuthorship W4292575168A5053660330 @default.
• W4292575168 hasAuthorship W4292575168A5058073627 @default.
• W4292575168 hasAuthorship W4292575168A5086428144 @default.
• W4292575168 hasConcept C100817775 @default.
• W4292575168 hasConcept C104317684 @default.
• W4292575168 hasConcept C109316439 @default.
• W4292575168 hasConcept C12554922 @default.
• W4292575168 hasConcept C135983454 @default.
• W4292575168 hasConcept C1491633281 @default.
• W4292575168 hasConcept C153911025 @default.
• W4292575168 hasConcept C185592680 @default.
• W4292575168 hasConcept C202751555 @default.
• W4292575168 hasConcept C2775925850 @default.
• W4292575168 hasConcept C28005876 @default.
• W4292575168 hasConcept C40017333 @default.
• W4292575168 hasConcept C54009773 @default.
• W4292575168 hasConcept C552990157 @default.
• W4292575168 hasConcept C55493867 @default.
• W4292575168 hasConcept C86803240 @default.
• W4292575168 hasConceptScore W4292575168C100817775 @default.
• W4292575168 hasConceptScore W4292575168C104317684 @default.
• W4292575168 hasConceptScore W4292575168C109316439 @default.
• W4292575168 hasConceptScore W4292575168C12554922 @default.
• W4292575168 hasConceptScore W4292575168C135983454 @default.
• W4292575168 hasConceptScore W4292575168C1491633281 @default.
• W4292575168 hasConceptScore W4292575168C153911025 @default.
• W4292575168 hasConceptScore W4292575168C185592680 @default.
• W4292575168 hasConceptScore W4292575168C202751555 @default.
• W4292575168 hasConceptScore W4292575168C2775925850 @default.
• W4292575168 hasConceptScore W4292575168C28005876 @default.
• W4292575168 hasConceptScore W4292575168C40017333 @default.
• W4292575168 hasConceptScore W4292575168C54009773 @default.
• W4292575168 hasConceptScore W4292575168C552990157 @default.
• W4292575168 hasConceptScore W4292575168C55493867 @default.
• W4292575168 hasConceptScore W4292575168C86803240 @default.
• W4292575168 hasFunder F4320321001 @default.
• W4292575168 hasFunder F4320322186 @default.
• W4292575168 hasIssue "43" @default.
• W4292575168 hasLocation W42925751681 @default.
• W4292575168 hasOpenAccess W4292575168 @default.
• W4292575168 hasPrimaryLocation W42925751681 @default.
• W4292575168 hasRelatedWork W1966995412 @default.
• W4292575168 hasRelatedWork W2021481096 @default.
• W4292575168 hasRelatedWork W2073678610 @default.

• next