Matches in SemOpenAlex for { <https://semopenalex.org/work/W4292595913> ?p ?o ?g. }
- W4292595913 endingPage "678" @default.
- W4292595913 startingPage "667" @default.
- W4292595913 abstract "Chronic COVID syndrome is characterized by chronic fatigue, myalgia, depression and sleep disturbances, similar to chronic fatigue syndrome (CFS) and fibromyalgia syndrome. Implementations of mitochondrial nutrients (MNs) with diet are important for the clinical effects antioxidant. We examined if use of an association of coenzyme Q10 and alpha lipoic acid (Requpero®) could reduce chronic covid symptoms. The Requpero study is a prospective observational study in which 174 patients, who had developed chronic-covid syndrome, were divided in two groups: The first one (116 patients) received coenzyme Q10 + alpha lipoic acid, and the second one (58 patients) did not receive any treatment. Primary outcome was reduction in Fatigue Severity Scale (FSS) in treatment group compared with control group. complete FSS response was reached most frequently in treatment group than in control group. A FSS complete response was reached in 62 (53.5%) patients in treatment group and in two (3.5%) patients in control group. A reduction in FSS core < 20% from baseline at T1 (non-response) was observed in 11 patients in the treatment group (9.5%) and in 15 patients in the control group (25.9%) (p < 0.0001). To date, this is the first study that tests the efficacy of coenzyme Q10 and alpha lipoic acid in chronic Covid syndrome. Primary and secondary outcomes were met. These results have to be confirmed through a double blind placebo controlled trial of longer duration." @default.
- W4292595913 created "2022-08-22" @default.
- W4292595913 creator A5003677392 @default.
- W4292595913 creator A5011251971 @default.
- W4292595913 creator A5022969534 @default.
- W4292595913 creator A5025804558 @default.
- W4292595913 creator A5028628840 @default.
- W4292595913 creator A5042206745 @default.
- W4292595913 creator A5069038189 @default.
- W4292595913 date "2022-08-22" @default.
- W4292595913 modified "2023-10-14" @default.
- W4292595913 title "Coenzyme Q10 + alpha lipoic acid for chronic COVID syndrome" @default.
- W4292595913 cites W133792508 @default.
- W4292595913 cites W1520568691 @default.
- W4292595913 cites W1574052502 @default.
- W4292595913 cites W1963655689 @default.
- W4292595913 cites W1966238900 @default.
- W4292595913 cites W1972130246 @default.
- W4292595913 cites W1983108385 @default.
- W4292595913 cites W1986568749 @default.
- W4292595913 cites W2004555581 @default.
- W4292595913 cites W2005853038 @default.
- W4292595913 cites W2007554763 @default.
- W4292595913 cites W2010118456 @default.
- W4292595913 cites W2018639545 @default.
- W4292595913 cites W2031084334 @default.
- W4292595913 cites W2036004607 @default.
- W4292595913 cites W2063444848 @default.
- W4292595913 cites W2063765492 @default.
- W4292595913 cites W2069206405 @default.
- W4292595913 cites W2101631166 @default.
- W4292595913 cites W2107771044 @default.
- W4292595913 cites W2121629072 @default.
- W4292595913 cites W2138961575 @default.
- W4292595913 cites W2144543799 @default.
- W4292595913 cites W2152901685 @default.
- W4292595913 cites W2158843422 @default.
- W4292595913 cites W2167384912 @default.
- W4292595913 cites W2171329987 @default.
- W4292595913 cites W2180615828 @default.
- W4292595913 cites W2403124317 @default.
- W4292595913 cites W2544056465 @default.
- W4292595913 cites W2582349744 @default.
- W4292595913 cites W2584281377 @default.
- W4292595913 cites W2731618083 @default.
- W4292595913 cites W2738996050 @default.
- W4292595913 cites W2778366284 @default.
- W4292595913 cites W2787254291 @default.
- W4292595913 cites W2898491742 @default.
- W4292595913 cites W2943370733 @default.
- W4292595913 cites W2943932740 @default.
- W4292595913 cites W2949451258 @default.
- W4292595913 cites W2959063900 @default.
- W4292595913 cites W2983579966 @default.
- W4292595913 cites W2999856368 @default.
- W4292595913 cites W3008568763 @default.
- W4292595913 cites W3009647858 @default.
- W4292595913 cites W3010429611 @default.
- W4292595913 cites W3012849736 @default.
- W4292595913 cites W3015228903 @default.
- W4292595913 cites W3022379136 @default.
- W4292595913 cites W3027187303 @default.
- W4292595913 cites W3033158347 @default.
- W4292595913 cites W3041493976 @default.
- W4292595913 cites W3045680995 @default.
- W4292595913 cites W3087185517 @default.
- W4292595913 cites W3087262009 @default.
- W4292595913 cites W3087308906 @default.
- W4292595913 cites W3089048389 @default.
- W4292595913 cites W3089319547 @default.
- W4292595913 cites W3097869695 @default.
- W4292595913 cites W3108848052 @default.
- W4292595913 cites W3117542080 @default.
- W4292595913 cites W3118462933 @default.
- W4292595913 cites W3119322361 @default.
- W4292595913 cites W3120387768 @default.
- W4292595913 cites W3123123255 @default.
- W4292595913 cites W3125153662 @default.
- W4292595913 cites W3135108774 @default.
- W4292595913 cites W3144796705 @default.
- W4292595913 cites W3158840448 @default.
- W4292595913 cites W3163666887 @default.
- W4292595913 cites W3169415007 @default.
- W4292595913 cites W3196177353 @default.
- W4292595913 cites W3204740690 @default.
- W4292595913 doi "https://doi.org/10.1007/s10238-022-00871-8" @default.
- W4292595913 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35994177" @default.
- W4292595913 hasPublicationYear "2022" @default.
- W4292595913 type Work @default.
- W4292595913 citedByCount "5" @default.
- W4292595913 countsByYear W42925959132023 @default.
- W4292595913 crossrefType "journal-article" @default.
- W4292595913 hasAuthorship W4292595913A5003677392 @default.
- W4292595913 hasAuthorship W4292595913A5011251971 @default.
- W4292595913 hasAuthorship W4292595913A5022969534 @default.
- W4292595913 hasAuthorship W4292595913A5025804558 @default.
- W4292595913 hasAuthorship W4292595913A5028628840 @default.
- W4292595913 hasAuthorship W4292595913A5042206745 @default.