FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4292609017> ?p ?o ?g. }

• W4292609017 abstract "There is a growing interest in continuous processing of the biopharmaceutical industry. However, the technology transfer from traditional batch-based processes is considered a challenge as protocol and tools still remain to be established for their usage at the manufacturing scale. Here, we present a model-based approach to design optimized perfusion cultures of Chinese Hamster Ovary cells using only the knowledge captured during small-scale fed-batch experiments. The novelty of the proposed model lies in the simplicity of its structure. Thanks to the introduction of a new catch-all variable representing a bulk of by-products secreted by the cells during their cultivation, the model was able to successfully predict cellular behavior under different operating modes without changes in its formalism. To our knowledge, this is the first experimentally validated model capable, with a single set of parameters, to capture culture dynamic under different operating modes and at different scales." @default.
• W4292609017 created "2022-08-22" @default.
• W4292609017 creator A5006492666 @default.
• W4292609017 creator A5029552605 @default.
• W4292609017 creator A5038165895 @default.
• W4292609017 creator A5063466800 @default.
• W4292609017 creator A5065458525 @default.
• W4292609017 creator A5078406215 @default.
• W4292609017 date "2022-08-22" @default.
• W4292609017 modified "2023-09-27" @default.
• W4292609017 title "Model-based intensification of CHO cell cultures: One-step strategy from fed-batch to perfusion" @default.
• W4292609017 cites W1773665598 @default.
• W4292609017 cites W1979782723 @default.
• W4292609017 cites W2005141109 @default.
• W4292609017 cites W2052859646 @default.
• W4292609017 cites W2110378444 @default.
• W4292609017 cites W2273267066 @default.
• W4292609017 cites W2529331386 @default.
• W4292609017 cites W2606676378 @default.
• W4292609017 cites W2797492982 @default.
• W4292609017 cites W2800956912 @default.
• W4292609017 cites W2884264646 @default.
• W4292609017 cites W2897746699 @default.
• W4292609017 cites W2901614545 @default.
• W4292609017 cites W2903436678 @default.
• W4292609017 cites W2944466104 @default.
• W4292609017 cites W2953260158 @default.
• W4292609017 cites W2960410044 @default.
• W4292609017 cites W2966080905 @default.
• W4292609017 cites W2994701212 @default.
• W4292609017 cites W3008811307 @default.
• W4292609017 cites W3009999522 @default.
• W4292609017 cites W3015214847 @default.
• W4292609017 cites W3016077459 @default.
• W4292609017 cites W3033699255 @default.
• W4292609017 cites W3049533068 @default.
• W4292609017 cites W3165727984 @default.
• W4292609017 cites W3172711957 @default.
• W4292609017 cites W3178104970 @default.
• W4292609017 cites W3198531740 @default.
• W4292609017 cites W3201962534 @default.
• W4292609017 cites W3212611295 @default.
• W4292609017 cites W3212678703 @default.
• W4292609017 cites W4205850303 @default.
• W4292609017 cites W4221033952 @default.
• W4292609017 cites W4223964283 @default.
• W4292609017 cites W4245988592 @default.
• W4292609017 doi "https://doi.org/10.3389/fbioe.2022.948905" @default.
• W4292609017 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36072286" @default.
• W4292609017 hasPublicationYear "2022" @default.
• W4292609017 type Work @default.
• W4292609017 citedByCount "1" @default.
• W4292609017 countsByYear W42926090172023 @default.
• W4292609017 crossrefType "journal-article" @default.
• W4292609017 hasAuthorship W4292609017A5006492666 @default.
• W4292609017 hasAuthorship W4292609017A5029552605 @default.
• W4292609017 hasAuthorship W4292609017A5038165895 @default.
• W4292609017 hasAuthorship W4292609017A5063466800 @default.
• W4292609017 hasAuthorship W4292609017A5065458525 @default.
• W4292609017 hasAuthorship W4292609017A5078406215 @default.
• W4292609017 hasBestOaLocation W42926090171 @default.
• W4292609017 hasConcept C121332964 @default.
• W4292609017 hasConcept C127413603 @default.
• W4292609017 hasConcept C138885662 @default.
• W4292609017 hasConcept C142362112 @default.
• W4292609017 hasConcept C150903083 @default.
• W4292609017 hasConcept C153349607 @default.
• W4292609017 hasConcept C172658912 @default.
• W4292609017 hasConcept C175656101 @default.
• W4292609017 hasConcept C183696295 @default.
• W4292609017 hasConcept C186060115 @default.
• W4292609017 hasConcept C199360897 @default.
• W4292609017 hasConcept C21880701 @default.
• W4292609017 hasConcept C27206212 @default.
• W4292609017 hasConcept C2778738651 @default.
• W4292609017 hasConcept C2778755073 @default.
• W4292609017 hasConcept C2781047461 @default.
• W4292609017 hasConcept C41008148 @default.
• W4292609017 hasConcept C54355233 @default.
• W4292609017 hasConcept C558565934 @default.
• W4292609017 hasConcept C62520636 @default.
• W4292609017 hasConcept C73301696 @default.
• W4292609017 hasConcept C81885089 @default.
• W4292609017 hasConcept C86803240 @default.
• W4292609017 hasConceptScore W4292609017C121332964 @default.
• W4292609017 hasConceptScore W4292609017C127413603 @default.
• W4292609017 hasConceptScore W4292609017C138885662 @default.
• W4292609017 hasConceptScore W4292609017C142362112 @default.
• W4292609017 hasConceptScore W4292609017C150903083 @default.
• W4292609017 hasConceptScore W4292609017C153349607 @default.
• W4292609017 hasConceptScore W4292609017C172658912 @default.
• W4292609017 hasConceptScore W4292609017C175656101 @default.
• W4292609017 hasConceptScore W4292609017C183696295 @default.
• W4292609017 hasConceptScore W4292609017C186060115 @default.
• W4292609017 hasConceptScore W4292609017C199360897 @default.
• W4292609017 hasConceptScore W4292609017C21880701 @default.
• W4292609017 hasConceptScore W4292609017C27206212 @default.
• W4292609017 hasConceptScore W4292609017C2778738651 @default.
• W4292609017 hasConceptScore W4292609017C2778755073 @default.
• W4292609017 hasConceptScore W4292609017C2781047461 @default.

• next