FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4292707591> ?p ?o ?g. }

• W4292707591 abstract "Although emerging evidence suggests that periodontitis might increase the risk of cancer, comorbidity and lifestyle behaviors, such as smoking and body mass index (BMI), may have confounded this reported association. This study aimed to investigate whether chronic periodontitis is associated with cancer risk using a large, nationwide database.We conducted a population-based, retrospective cohort study using data from the Korean National Health Insurance Cohort Database obtained between January 2003 and December 2015. We included 713,201 individuals without a history of cancer who were followed up to 10 years. Confounding factors included demographic factors (age, sex, income, and residential area), lifestyle behaviors (smoking history and BMI), and comorbidities, such as hypertension, diabetes, heart failure, and pulmonary disease, using the Charlson Comorbidity Index. Multivariable Cox regression analysis was applied to estimate the adjusted hazard ratio (aHR) for cancer risk.Of the 713,201 participants, 53,075 had periodontitis and were placed in the periodontitis group; the remaining 660,126 individuals were included as the control group. Overall, the cumulative incidence of cancer in the periodontitis group was 2.2 times higher than that in the control group. The periodontitis group had an increased risk of total cancer compared to the control group after adjusting for age, sex, comorbidities, BMI, and smoking history (aHR, 1.129; 95% confidence interval [CI], 1.089-1.171; P<0.0001). When examining specific cancer types, significant associations were also observed between periodontitis and stomach cancer (aHR, 1.136; 95% CI, 1.042-1.239; P=0.0037), colon cancer (aHR, 1.129; 95% CI, 1.029-1.239; P=0.0105), lung cancer (aHR, 1.127; 95% CI, 1.008-1.260; P=0.0353), bladder cancer (aHR, 1.307; 95% CI, 1.071-1.595; P=0.0085), thyroid cancer (aHR, 1.191; 95% CI, 1.085-1.308; P=0.0002), and leukemia (aHR, 1.394; 95% CI, 1.039-1.872; P=0.0270). There was no significant association between the development of secondary malignancy and periodontitis in cancer survivors who were alive 5 years after they were diagnosed with the primary malignancy.Periodontal disease, including periodontitis, was associated with increased risk of cancer, which persisted after controlling for confounding factors. Further prospective research is warranted to establish a causal relationship." @default.
• W4292707591 created "2022-08-23" @default.
• W4292707591 creator A5007773065 @default.
• W4292707591 creator A5012101460 @default.
• W4292707591 creator A5013593835 @default.
• W4292707591 creator A5018855696 @default.
• W4292707591 creator A5028496861 @default.
• W4292707591 creator A5046176363 @default.
• W4292707591 creator A5051983148 @default.
• W4292707591 creator A5057910165 @default.
• W4292707591 creator A5079286249 @default.
• W4292707591 creator A5079351195 @default.
• W4292707591 creator A5083550513 @default.
• W4292707591 creator A5089438616 @default.
• W4292707591 date "2022-08-23" @default.
• W4292707591 modified "2023-10-14" @default.
• W4292707591 title "Periodontal disease and cancer risk: A nationwide population-based cohort study" @default.
• W4292707591 cites W1990515033 @default.
• W4292707591 cites W2000445173 @default.
• W4292707591 cites W2006292369 @default.
• W4292707591 cites W2021838232 @default.
• W4292707591 cites W2073101005 @default.
• W4292707591 cites W2096139589 @default.
• W4292707591 cites W2099951919 @default.
• W4292707591 cites W2102144390 @default.
• W4292707591 cites W2124900063 @default.
• W4292707591 cites W2147331510 @default.
• W4292707591 cites W2148510247 @default.
• W4292707591 cites W2156951316 @default.
• W4292707591 cites W2159128449 @default.
• W4292707591 cites W2167126167 @default.
• W4292707591 cites W2169722961 @default.
• W4292707591 cites W2199914463 @default.
• W4292707591 cites W2281104822 @default.
• W4292707591 cites W2607294078 @default.
• W4292707591 cites W2607672964 @default.
• W4292707591 cites W2727763166 @default.
• W4292707591 cites W2740103697 @default.
• W4292707591 cites W2783423687 @default.
• W4292707591 cites W2802852552 @default.
• W4292707591 cites W2809416758 @default.
• W4292707591 cites W2811395700 @default.
• W4292707591 cites W2897037806 @default.
• W4292707591 cites W2904476258 @default.
• W4292707591 cites W2919696154 @default.
• W4292707591 cites W2956655325 @default.
• W4292707591 cites W2969617932 @default.
• W4292707591 cites W2999580311 @default.
• W4292707591 cites W3010457767 @default.
• W4292707591 cites W3109524876 @default.
• W4292707591 cites W3117201729 @default.
• W4292707591 cites W3125030132 @default.
• W4292707591 cites W3135101456 @default.
• W4292707591 cites W3203558366 @default.
• W4292707591 cites W3210311404 @default.
• W4292707591 cites W4246944221 @default.
• W4292707591 cites W4281807572 @default.
• W4292707591 doi "https://doi.org/10.3389/fonc.2022.901098" @default.
• W4292707591 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36081548" @default.
• W4292707591 hasPublicationYear "2022" @default.
• W4292707591 type Work @default.
• W4292707591 citedByCount "4" @default.
• W4292707591 countsByYear W42927075912023 @default.
• W4292707591 crossrefType "journal-article" @default.
• W4292707591 hasAuthorship W4292707591A5007773065 @default.
• W4292707591 hasAuthorship W4292707591A5012101460 @default.
• W4292707591 hasAuthorship W4292707591A5013593835 @default.
• W4292707591 hasAuthorship W4292707591A5018855696 @default.
• W4292707591 hasAuthorship W4292707591A5028496861 @default.
• W4292707591 hasAuthorship W4292707591A5046176363 @default.
• W4292707591 hasAuthorship W4292707591A5051983148 @default.
• W4292707591 hasAuthorship W4292707591A5057910165 @default.
• W4292707591 hasAuthorship W4292707591A5079286249 @default.
• W4292707591 hasAuthorship W4292707591A5079351195 @default.
• W4292707591 hasAuthorship W4292707591A5083550513 @default.
• W4292707591 hasAuthorship W4292707591A5089438616 @default.
• W4292707591 hasBestOaLocation W42927075911 @default.
• W4292707591 hasConcept C121608353 @default.
• W4292707591 hasConcept C126322002 @default.
• W4292707591 hasConcept C201903717 @default.
• W4292707591 hasConcept C207103383 @default.
• W4292707591 hasConcept C2779159551 @default.
• W4292707591 hasConcept C2780221984 @default.
• W4292707591 hasConcept C2780385504 @default.
• W4292707591 hasConcept C2908647359 @default.
• W4292707591 hasConcept C44249647 @default.
• W4292707591 hasConcept C50382708 @default.
• W4292707591 hasConcept C71924100 @default.
• W4292707591 hasConcept C72563966 @default.
• W4292707591 hasConcept C77350462 @default.
• W4292707591 hasConcept C99454951 @default.
• W4292707591 hasConceptScore W4292707591C121608353 @default.
• W4292707591 hasConceptScore W4292707591C126322002 @default.
• W4292707591 hasConceptScore W4292707591C201903717 @default.
• W4292707591 hasConceptScore W4292707591C207103383 @default.
• W4292707591 hasConceptScore W4292707591C2779159551 @default.
• W4292707591 hasConceptScore W4292707591C2780221984 @default.
• W4292707591 hasConceptScore W4292707591C2780385504 @default.
• W4292707591 hasConceptScore W4292707591C2908647359 @default.
• W4292707591 hasConceptScore W4292707591C44249647 @default.

• next