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- W4292767416 abstract "A pair of novel trimeric indole alkaloid enantiomers [(±)-8], five new bisindole alkaloids [4-7 and (±)-9], and three pairs of new monomeric indole alkaloid enantiomers [(±)-1-(±)-3], together with seven known alkaloids (10-16), were isolated from the bark of Acacia confusa. Their structures were determined on the basis of spectroscopic methods, especially by NMR data analyses combined with single-crystal X-ray diffraction and electronic circular dichroism analyses. Compounds 4 and 11-16 exhibited significant antinociceptive activities in an acetic acid-induced writhing test. Compounds (+)-9 and (-)-9 displayed anti-inflammatory activities through the inhibition of the NF-κB pathway, with inhibitory rates of 68.9% and 59.5%, respectively, at a concentration of 10 µM." @default.
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- W4292767416 date "2022-08-23" @default.
- W4292767416 modified "2023-09-28" @default.
- W4292767416 title "Indole alkaloids from the bark of <i>Acacia confusa</i> and their potential antinociceptive and anti-inflammatory activities" @default.
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- W4292767416 doi "https://doi.org/10.1080/10286020.2022.2093195" @default.
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