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- W4292839008 abstract "The research group proposed that the mechanism of Feature Identification based Quality Assessment (FIQA) of Traditional Chinese Medicine (TCM) can be explained according to the relationship between the Feature of TCM and the Pharmacodynamic Components representing the holistic effect of TCM. Gastrodiae Rhizoma (GR) was selected as the research object to reveal the close relationship between Feature and the quality of TCM.In this study, the Feature such as Shape, Color, Odour and Taste of GR are quantified by the electronic nose, electronic tongue, and other instruments. Then, the Pharmacodynamic Components Group (PCG) of GR was determined which could reflect the holistic effect of GR by spectrum effect relationship analysis. By analyzing the correlation between the Feature and the content of PCG, the mechanism of FIQA of GR was determined.The quantitative results of Shape, Color, Odour and Taste of GR from different sources were significantly different. Six components were selected as the PCG, which can represent the holistic effect of GR in the aspect of the neuroprotective effect. There was a good correlation between the components in the PCG and Feature.The quality of GR can be determined quantitatively according to its Shape, Color, Odour and Taste. The mechanism of FIQA of TCM can be explained according to the relationship between the Shape of TCM and the Pharmacodynamic Components representing the quality of TCM. The revelation of this mechanism reflects the holistic characteristics of the multi-component synergistic effect of TCM. This study provides a reference research method for revealing the mechanism of FIQA of TCM." @default.
- W4292839008 created "2022-08-24" @default.
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- W4292839008 date "2022-08-01" @default.
- W4292839008 modified "2023-09-27" @default.
- W4292839008 title "A new method for studying the mechanism of “Feature Identification based quality assessment” of Traditional Chinese Medicine, taking Gastrodiae Rhizoma as an example" @default.
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- W4292839008 doi "https://doi.org/10.1016/j.heliyon.2022.e10354" @default.
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