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- W4292959968 abstract "Genetic mapping in 2-generation crosses requires genotyping, usually performed with single nucleotide polymorphism markers arrays which provide high-density genetic information. However, genetic analysis on raw genotypes can lead to spurious or unreliable results due to defective single nucleotide polymorphism assays or wrong genotype interpretation. Here, we introduce stuart, an open-source R package, which analyzes raw genotyping data to filter single nucleotide polymorphism markers based on informativeness, Mendelian inheritance pattern, and consistency with parental genotypes. The functions of this package provide a curation pipeline and formatting adequate for genetic analysis with the R/qtl package. stuart is available with detailed documentation from https://gitlab.pasteur.fr/mouselab/stuart/." @default.
- W4292959968 created "2022-08-24" @default.
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- W4292959968 date "2022-08-24" @default.
- W4292959968 modified "2023-10-02" @default.
- W4292959968 title "stuart: an R package for the curation of SNP genotypes from experimental crosses" @default.
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- W4292959968 doi "https://doi.org/10.1093/g3journal/jkac219" @default.
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