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• W4293052015 abstract "To investigate the diversity, distribution, persistence, and prevalence of stress survival and resistance genes of Listeria monocytogenes clones dominating in food processing environments in Norway, genome sequences from 769 L. monocytogenes isolates from food industry environments, foods, and raw materials (512 of which were sequenced in the present study) were subjected to whole-genome multilocus sequence typing (wgMLST), single-nucleotide polymorphism (SNP), and comparative genomic analyses. The data set comprised isolates from nine meat and six salmon processing facilities in Norway collected over a period of three decades. The most prevalent clonal complex (CC) was CC121, found in 10 factories, followed by CC7, CC8, and CC9, found in 7 factories each. Overall, 72% of the isolates were classified as persistent, showing 20 or fewer wgMLST allelic differences toward an isolate found in the same factory in a different calendar year. Moreover, over half of the isolates (56%) showed this level of genetic similarity toward an isolate collected from a different food processing facility. These were designated as pervasive strains, defined as clusters with the same level of genetic similarity as persistent strains but isolated from different factories. The prevalence of genetic determinants associated with increased survival in food processing environments, including heavy metal and biocide resistance determinants, stress response genes, and inlA truncation mutations, showed a highly significant increase among pervasive isolates but not among persistent isolates. Furthermore, these genes were significantly more prevalent among the isolates from food processing environments compared to in isolates from natural and rural environments (n = 218) and clinical isolates (n = 111) from Norway. IMPORTANCE Listeria monocytogenes can persist in food processing environments for months to decades and spread through the food system by, e.g., contaminated raw materials. Knowledge of the distribution and diversity of L. monocytogenes is important in outbreak investigations and is essential to effectively track and control this pathogen in the food system. The present study presents a comprehensive overview of the prevalence of persistent clones and of the diversity of L. monocytogenes in Norwegian food processing facilities. The results demonstrate extensive spread of highly similar strains throughout the Norwegian food system, in that 56% of the 769 collected isolates from food processing factories belonged to clusters of L. monocytogenes identified in more than one facility. These strains were associated with an overall increase in the prevalence of plasmids and determinants of heavy metal and biocide resistance, as well as other genetic elements associated with stress survival mechanisms and persistence." @default.
• W4293052015 created "2022-08-25" @default.
• W4293052015 creator A5039179482 @default.
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• W4293052015 date "2022-09-22" @default.
• W4293052015 modified "2023-10-10" @default.
• W4293052015 title "Pervasive <i>Listeria monocytogenes</i> Is Common in the Norwegian Food System and Is Associated with Increased Prevalence of Stress Survival and Resistance Determinants" @default.
• W4293052015 cites W1162253361 @default.
• W4293052015 cites W1601323201 @default.
• W4293052015 cites W1670595433 @default.
• W4293052015 cites W1806778326 @default.
• W4293052015 cites W1851795517 @default.
• W4293052015 cites W1961082387 @default.
• W4293052015 cites W1964667273 @default.
• W4293052015 cites W1969612992 @default.
• W4293052015 cites W1991907825 @default.
• W4293052015 cites W1996835973 @default.
• W4293052015 cites W2004669054 @default.
• W4293052015 cites W2007641004 @default.
• W4293052015 cites W2010140498 @default.
• W4293052015 cites W2022219641 @default.
• W4293052015 cites W2043741824 @default.
• W4293052015 cites W2049907053 @default.
• W4293052015 cites W2054709656 @default.
• W4293052015 cites W2058383486 @default.
• W4293052015 cites W2062494618 @default.
• W4293052015 cites W2071904317 @default.
• W4293052015 cites W2073250779 @default.
• W4293052015 cites W2079602979 @default.
• W4293052015 cites W2085849559 @default.
• W4293052015 cites W2107940314 @default.
• W4293052015 cites W2110592347 @default.
• W4293052015 cites W2120902911 @default.
• W4293052015 cites W2126334037 @default.
• W4293052015 cites W2134852597 @default.
• W4293052015 cites W2135695553 @default.
• W4293052015 cites W2163293919 @default.
• W4293052015 cites W2171888002 @default.
• W4293052015 cites W2245688640 @default.
• W4293052015 cites W2255901834 @default.
• W4293052015 cites W2259709515 @default.
• W4293052015 cites W2272655888 @default.
• W4293052015 cites W2293595916 @default.
• W4293052015 cites W2317031129 @default.
• W4293052015 cites W2343336356 @default.
• W4293052015 cites W2345564731 @default.
• W4293052015 cites W2347159151 @default.
• W4293052015 cites W2377554765 @default.
• W4293052015 cites W2509538394 @default.
• W4293052015 cites W2530546106 @default.
• W4293052015 cites W2532921301 @default.
• W4293052015 cites W2551543514 @default.
• W4293052015 cites W2593229126 @default.
• W4293052015 cites W2608890447 @default.
• W4293052015 cites W2618344387 @default.
• W4293052015 cites W2620676694 @default.
• W4293052015 cites W2625579714 @default.
• W4293052015 cites W2752828584 @default.
• W4293052015 cites W2768232968 @default.
• W4293052015 cites W2772827032 @default.
• W4293052015 cites W2793598086 @default.
• W4293052015 cites W2794227253 @default.
• W4293052015 cites W2796284286 @default.
• W4293052015 cites W2797256792 @default.
• W4293052015 cites W2801886331 @default.
• W4293052015 cites W2805550232 @default.
• W4293052015 cites W2808352813 @default.
• W4293052015 cites W2808713854 @default.
• W4293052015 cites W2883251903 @default.
• W4293052015 cites W2886278910 @default.
• W4293052015 cites W2901550377 @default.
• W4293052015 cites W2902995589 @default.
• W4293052015 cites W2903928977 @default.
• W4293052015 cites W2918747503 @default.
• W4293052015 cites W2927973997 @default.
• W4293052015 cites W2937074213 @default.
• W4293052015 cites W2942003310 @default.
• W4293052015 cites W2943937192 @default.
• W4293052015 cites W2949007191 @default.
• W4293052015 cites W2958010993 @default.
• W4293052015 cites W2963024031 @default.
• W4293052015 cites W2969057613 @default.
• W4293052015 cites W2981573822 @default.
• W4293052015 cites W2990105179 @default.
• W4293052015 cites W2998698502 @default.
• W4293052015 cites W3001927223 @default.
• W4293052015 cites W3012705933 @default.
• W4293052015 cites W3025048250 @default.
• W4293052015 cites W3029109637 @default.
• W4293052015 cites W3035310299 @default.
• W4293052015 cites W3036419484 @default.
• W4293052015 cites W3080539319 @default.
• W4293052015 cites W3099607811 @default.
• W4293052015 cites W3109831007 @default.
• W4293052015 cites W3115932431 @default.

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