FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4293083635> ?p ?o ?g. }

• W4293083635 endingPage "46" @default.
• W4293083635 startingPage "42" @default.
• W4293083635 abstract "Metastatic and incurable cancers of the gynaecological tract (FGTC) represent a major global health burden. Systemic treatment has modest efficacy and radiotherapy is often used for local symptoms. This study combines experience from two large UK centres in palliative radiotherapy for gynaecological cancers.Pooled data from two major centres was analysed. Advanced FGTC patients who received at least one fraction of palliative radiotherapy to the pelvis between 2013 and 2018 were included. Data collected included demographic and tumour details, radiotherapy dose fractionation and details of previous and subsequent treatment. Response was defined in terms of toxicity, symptomatic response and survival. Comorbidities were recorded using a modified ACE 27 score which is adjusted for the presence of uncontrolled FGTC in all the patients.A total of 184 patients were included for treatment response and toxicity; survival data was available for 165 patients. Subjective response in pre-radiotherapy symptoms was documented in 80.4%. Grade 3 or worse gastrointestinal, urinary and other (vomiting, fatigue, pain) toxicity incidence was 2.2%, 3.8%, and 2.7% respectively. No statistically significant correlation between the prescribed EQD210 and symptom control or toxicity was seen. 1 year overall survival was 25.1% (median 5.9 months). Absent distant metastases, completion of the intended course of radiotherapy, response to radiotherapy, and receipt of further lines of treatment were independent prognostic factors.Palliative radiotherapy is effective for symptoms of advanced FGTC with low toxicity. The absence of a dose response argues for short low dose palliative radiotherapy schedules to be used." @default.
• W4293083635 created "2022-08-26" @default.
• W4293083635 creator A5003310622 @default.
• W4293083635 creator A5011187215 @default.
• W4293083635 creator A5020453607 @default.
• W4293083635 creator A5039495148 @default.
• W4293083635 creator A5041859071 @default.
• W4293083635 creator A5053342848 @default.
• W4293083635 creator A5059184501 @default.
• W4293083635 creator A5076203779 @default.
• W4293083635 date "2022-10-01" @default.
• W4293083635 modified "2023-10-16" @default.
• W4293083635 title "Palliative radiotherapy in cancers of female genital tract: Outcomes and prognostic factors" @default.
• W4293083635 cites W1967038049 @default.
• W4293083635 cites W1968055534 @default.
• W4293083635 cites W1975929167 @default.
• W4293083635 cites W1992635100 @default.
• W4293083635 cites W1997874428 @default.
• W4293083635 cites W2002297401 @default.
• W4293083635 cites W2003865781 @default.
• W4293083635 cites W2012980054 @default.
• W4293083635 cites W2030962744 @default.
• W4293083635 cites W2031112188 @default.
• W4293083635 cites W2034949926 @default.
• W4293083635 cites W2043528439 @default.
• W4293083635 cites W2052947296 @default.
• W4293083635 cites W2059519287 @default.
• W4293083635 cites W2081778499 @default.
• W4293083635 cites W2083789091 @default.
• W4293083635 cites W2106945904 @default.
• W4293083635 cites W2134796844 @default.
• W4293083635 cites W2142660070 @default.
• W4293083635 cites W2145113216 @default.
• W4293083635 cites W2310882531 @default.
• W4293083635 cites W2505617467 @default.
• W4293083635 cites W2884284690 @default.
• W4293083635 cites W2946898842 @default.
• W4293083635 cites W3074772937 @default.
• W4293083635 cites W3126113798 @default.
• W4293083635 cites W4200606284 @default.
• W4293083635 cites W4213279769 @default.
• W4293083635 doi "https://doi.org/10.1016/j.radonc.2022.07.023" @default.
• W4293083635 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35964765" @default.
• W4293083635 hasPublicationYear "2022" @default.
• W4293083635 type Work @default.
• W4293083635 citedByCount "2" @default.
• W4293083635 countsByYear W42930836352023 @default.
• W4293083635 crossrefType "journal-article" @default.
• W4293083635 hasAuthorship W4293083635A5003310622 @default.
• W4293083635 hasAuthorship W4293083635A5011187215 @default.
• W4293083635 hasAuthorship W4293083635A5020453607 @default.
• W4293083635 hasAuthorship W4293083635A5039495148 @default.
• W4293083635 hasAuthorship W4293083635A5041859071 @default.
• W4293083635 hasAuthorship W4293083635A5053342848 @default.
• W4293083635 hasAuthorship W4293083635A5059184501 @default.
• W4293083635 hasAuthorship W4293083635A5076203779 @default.
• W4293083635 hasConcept C126322002 @default.
• W4293083635 hasConcept C143998085 @default.
• W4293083635 hasConcept C159110408 @default.
• W4293083635 hasConcept C2780580376 @default.
• W4293083635 hasConcept C29730261 @default.
• W4293083635 hasConcept C2994186709 @default.
• W4293083635 hasConcept C509974204 @default.
• W4293083635 hasConcept C71924100 @default.
• W4293083635 hasConceptScore W4293083635C126322002 @default.
• W4293083635 hasConceptScore W4293083635C143998085 @default.
• W4293083635 hasConceptScore W4293083635C159110408 @default.
• W4293083635 hasConceptScore W4293083635C2780580376 @default.
• W4293083635 hasConceptScore W4293083635C29730261 @default.
• W4293083635 hasConceptScore W4293083635C2994186709 @default.
• W4293083635 hasConceptScore W4293083635C509974204 @default.
• W4293083635 hasConceptScore W4293083635C71924100 @default.
• W4293083635 hasLocation W42930836351 @default.
• W4293083635 hasLocation W42930836352 @default.
• W4293083635 hasOpenAccess W4293083635 @default.
• W4293083635 hasPrimaryLocation W42930836351 @default.
• W4293083635 hasRelatedWork W1496967564 @default.
• W4293083635 hasRelatedWork W2033179406 @default.
• W4293083635 hasRelatedWork W2100269289 @default.
• W4293083635 hasRelatedWork W2220345284 @default.
• W4293083635 hasRelatedWork W2363890076 @default.
• W4293083635 hasRelatedWork W2384708512 @default.
• W4293083635 hasRelatedWork W2728001136 @default.
• W4293083635 hasRelatedWork W2778716 @default.
• W4293083635 hasRelatedWork W4224493732 @default.
• W4293083635 hasRelatedWork W4290878809 @default.
• W4293083635 hasVolume "175" @default.
• W4293083635 isParatext "false" @default.
• W4293083635 isRetracted "false" @default.
• W4293083635 workType "article" @default.