Matches in SemOpenAlex for { <https://semopenalex.org/work/W4293092008> ?p ?o ?g. }
- W4293092008 endingPage "S11" @default.
- W4293092008 startingPage "S4" @default.
- W4293092008 abstract "Objective: Many studies have revealed the prominent roles of mast cells in wound healing, including inflammatory reactions, angiogenesis and extracellular matrix reabsorption. In the present study, we aimed to assess the probable therapeutic features of bromelain on wound contraction and mast cell degranulation in wound healing in experimental diabetic animals. Method: Male rats were grouped as control, vehicle and experiment. Skin wounds were generated in all groups. Treatments were applied with distilled water and with bromelain (BR) intraperitoneally in the vehicle and experimental groups, respectively. Following skin wound generation, animals were euthanised on days 3, 5, 7 and 15. We gathered 16,800 microscopic images to count the mast cells and degranulation level (Image J software). The wound contraction index was assessed both microscopically (Image J software) and macroscopically (time-lapse photography). The meshwork evaluation method was used to assess wound healing. Results: Time-lapse photography revealed that the BR significantly (p<0.05) accelerated wound contraction and healing. BR significantly (p<0.05) increased the total number of mast cells in all experimental groups on days 5 and 7. The count of grade III (degranulated) mast cells was reduced significantly (p<0.05) on days 5 and 7 in experimental groups compared to control and vehicle groups. Conclusion: In this study, the rate of wound healing was accelerated considerably following BR administration. In addition, this agent decreased the count of degranulated mast cells, leading to wound contraction and healing." @default.
- W4293092008 created "2022-08-26" @default.
- W4293092008 creator A5010481716 @default.
- W4293092008 creator A5012507404 @default.
- W4293092008 creator A5023553555 @default.
- W4293092008 creator A5036727854 @default.
- W4293092008 creator A5036876186 @default.
- W4293092008 creator A5041978754 @default.
- W4293092008 date "2022-08-01" @default.
- W4293092008 modified "2023-09-25" @default.
- W4293092008 title "Effect of bromelain on mast cell numbers and degranulation in diabetic rat wound healing" @default.
- W4293092008 cites W1590104418 @default.
- W4293092008 cites W1855671110 @default.
- W4293092008 cites W1982386486 @default.
- W4293092008 cites W1986308133 @default.
- W4293092008 cites W2005479975 @default.
- W4293092008 cites W2027291449 @default.
- W4293092008 cites W2031968433 @default.
- W4293092008 cites W2043706061 @default.
- W4293092008 cites W2060425936 @default.
- W4293092008 cites W2082519107 @default.
- W4293092008 cites W2089176039 @default.
- W4293092008 cites W2092346711 @default.
- W4293092008 cites W2098381099 @default.
- W4293092008 cites W2134625151 @default.
- W4293092008 cites W2141737309 @default.
- W4293092008 cites W2149955121 @default.
- W4293092008 cites W2157605152 @default.
- W4293092008 cites W2157745445 @default.
- W4293092008 cites W2170785232 @default.
- W4293092008 cites W2187041392 @default.
- W4293092008 cites W2261410883 @default.
- W4293092008 cites W2498749763 @default.
- W4293092008 cites W2560203277 @default.
- W4293092008 cites W2622263840 @default.
- W4293092008 cites W2765708736 @default.
- W4293092008 cites W2788452353 @default.
- W4293092008 cites W2793801139 @default.
- W4293092008 cites W2800548936 @default.
- W4293092008 cites W2883108547 @default.
- W4293092008 cites W2904175639 @default.
- W4293092008 cites W2911916770 @default.
- W4293092008 cites W2936462598 @default.
- W4293092008 cites W3008714024 @default.
- W4293092008 cites W3014961299 @default.
- W4293092008 cites W3019591016 @default.
- W4293092008 cites W3085298651 @default.
- W4293092008 cites W3086039149 @default.
- W4293092008 cites W3195098971 @default.
- W4293092008 cites W4229688459 @default.
- W4293092008 doi "https://doi.org/10.12968/jowc.2022.31.sup8.s4" @default.
- W4293092008 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36004940" @default.
- W4293092008 hasPublicationYear "2022" @default.
- W4293092008 type Work @default.
- W4293092008 citedByCount "0" @default.
- W4293092008 crossrefType "journal-article" @default.
- W4293092008 hasAuthorship W4293092008A5010481716 @default.
- W4293092008 hasAuthorship W4293092008A5012507404 @default.
- W4293092008 hasAuthorship W4293092008A5023553555 @default.
- W4293092008 hasAuthorship W4293092008A5036727854 @default.
- W4293092008 hasAuthorship W4293092008A5036876186 @default.
- W4293092008 hasAuthorship W4293092008A5041978754 @default.
- W4293092008 hasConcept C126322002 @default.
- W4293092008 hasConcept C141071460 @default.
- W4293092008 hasConcept C163415756 @default.
- W4293092008 hasConcept C170493617 @default.
- W4293092008 hasConcept C203014093 @default.
- W4293092008 hasConcept C2779726688 @default.
- W4293092008 hasConcept C2780269544 @default.
- W4293092008 hasConcept C49802076 @default.
- W4293092008 hasConcept C71924100 @default.
- W4293092008 hasConceptScore W4293092008C126322002 @default.
- W4293092008 hasConceptScore W4293092008C141071460 @default.
- W4293092008 hasConceptScore W4293092008C163415756 @default.
- W4293092008 hasConceptScore W4293092008C170493617 @default.
- W4293092008 hasConceptScore W4293092008C203014093 @default.
- W4293092008 hasConceptScore W4293092008C2779726688 @default.
- W4293092008 hasConceptScore W4293092008C2780269544 @default.
- W4293092008 hasConceptScore W4293092008C49802076 @default.
- W4293092008 hasConceptScore W4293092008C71924100 @default.
- W4293092008 hasIssue "Sup8" @default.
- W4293092008 hasLocation W42930920081 @default.
- W4293092008 hasLocation W42930920082 @default.
- W4293092008 hasOpenAccess W4293092008 @default.
- W4293092008 hasPrimaryLocation W42930920081 @default.
- W4293092008 hasRelatedWork W1456597060 @default.
- W4293092008 hasRelatedWork W1991211715 @default.
- W4293092008 hasRelatedWork W1998397846 @default.
- W4293092008 hasRelatedWork W2045958004 @default.
- W4293092008 hasRelatedWork W2049458831 @default.
- W4293092008 hasRelatedWork W2071584061 @default.
- W4293092008 hasRelatedWork W2143825956 @default.
- W4293092008 hasRelatedWork W2512190522 @default.
- W4293092008 hasRelatedWork W2921953980 @default.
- W4293092008 hasRelatedWork W2976621855 @default.
- W4293092008 hasVolume "31" @default.
- W4293092008 isParatext "false" @default.
- W4293092008 isRetracted "false" @default.