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• W4293149969 abstract "Abstract Aim The purpose of our study was to evaluate the antibacterial activities and dentin bond strengths of silver nanoparticles (Ag NPs) and silver nano-graphene oxide nanocomposites (Ag@nGO NCs) produced by green and chemical synthesis method added to dental adhesive. Methods Ag NPs were produced by green synthesis (B-Ag NPs) and chemical synthesis methods (C-Ag NPs) and deposited on nGO (nano-graphene oxide). Ag NPs and Ag@nGO NCs (0.05% w/w) were added to primer and bond (Clearfil SE Bond). Group 1: control, Group 2: nGO, Group 3: B-Ag NPs, Group 4: B-Ag@nGO NCs, Group 5: C-Ag NPs, Group 6: C-Ag@nGO NCs. S. Mutans live/dead assay analysis, MTT metabolic activity test, agar disc diffusion test, lactic acid production and colony forming units (CFUs) tests were performed. Bond strength values were determined by microtensile test. Failure types were determined by evaluating with SEM. Statistical analysis was performed using one-way ANOVA and two-way ANOVA (p < 0.05). Results There was a difference between the groups in the viable bacteria ratio and lactic acid production tests (p < 0.05). When the inhibition zone and S. Mutans CFUs were evaluated, there was no difference between Group 3 and Group 4 (p > 0.05), but there was a difference between the other groups (p < 0.05). When metabolic activity of S. Mutans was evaluated, there was a difference between Group 1 and other groups, and between Group 2 and Group 5 and Group 6 (p < 0.05). There was no difference between the groups in the microtensile bond strength values (p > 0.05). Conclusion Adhesives containing B-Ag NPs and B-Ag@nGO NCs provided sufficient antibacterial activity and did not reduce bond strength values. Clinical Significance: The addition of biocompatible B-Ag NPs and B-Ag@nGO NCs to the adhesive system increased the antibacterial effect by maintaining the bond strength of the adhesive. Antibacterial adhesives can increase the restoration life by protecting the tooth-adhesive interface." @default.
• W4293149969 created "2022-08-27" @default.
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• W4293149969 date "2022-08-26" @default.
• W4293149969 modified "2023-09-23" @default.
• W4293149969 title "Evaluation of the Antibacterial Activity of Dental Adhesive Containing Biocompatible Silver Nanoparticles Decorated Nano Graphene Oxide Nanocomposites (Ag@nGO NCs) and Its Effect on Bond Strength to Dentine" @default.
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• W4293149969 doi "https://doi.org/10.21203/rs.3.rs-1956042/v1" @default.
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