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- W4293162105 abstract "Merck & Co. recently reported one of the first mRNA display-derived clinical candidates in a bioavailable inhibitor of proprotein convertase subtilisin/kexin type 9 (PCSK9). Herein, we discuss the chemical and pharmacological challenges surmounted in bringing this compound to trials and the current outlook for mRNA display-based therapeutic development." @default.
- W4293162105 created "2022-08-27" @default.
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- W4293162105 date "2022-08-26" @default.
- W4293162105 modified "2023-10-01" @default.
- W4293162105 title "mRNA Display Reaches for the Clinic with New PCSK9 Inhibitor" @default.
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- W4293162105 doi "https://doi.org/10.1021/acsmedchemlett.2c00319" @default.
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