FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4293169161> ?p ?o ?g. }

• W4293169161 endingPage "1844" @default.
• W4293169161 startingPage "1844" @default.
• W4293169161 abstract "The second human pegivirus (HPgV-2) is a virus discovered in the plasma of a hepatitis C virus (HCV)-infected patient in 2015 belonging to the pegiviruses of the family Flaviviridae. HPgV-2 has been proved to be epidemiologically associated with and structurally similar to HCV but unrelated to HCV disease and non-pathogenic, but its natural history and tissue tropism remain unclear. HPgV-2 is a unique RNA virus sharing the features of HCV and the first human pegivirus (HPgV-1 or GBV-C). Moreover, distinct from most RNA viruses such as HCV, HPgV-1 and human immunodeficiency virus (HIV), HPgV-2 exhibits much lower genomic diversity, with a high global sequence identity ranging from 93.5 to 97.5% and significantly lower intra-host variation than HCV. The mechanisms underlying the conservation of the HPgV-2 genome are not clear but may include efficient innate immune responses, low immune selection pressure and, possibly, the unique features of the viral RNA-dependent RNA polymerase (RdRP). In this review, we summarize the prevalence, pathogenicity and genetic diversity of HPgV-2 and discuss the possible reasons for the uniformity of its genome sequence, which should elucidate the implications of RNA virus fidelity for attenuated viral vaccines." @default.
• W4293169161 created "2022-08-27" @default.
• W4293169161 creator A5003888491 @default.
• W4293169161 creator A5037873650 @default.
• W4293169161 creator A5045872492 @default.
• W4293169161 creator A5059119798 @default.
• W4293169161 creator A5061268334 @default.
• W4293169161 creator A5072866563 @default.
• W4293169161 date "2022-08-23" @default.
• W4293169161 modified "2023-09-25" @default.
• W4293169161 title "The Second Human Pegivirus, a Non-Pathogenic RNA Virus with Low Prevalence and Minimal Genetic Diversity" @default.
• W4293169161 cites W1943125084 @default.
• W4293169161 cites W1981720935 @default.
• W4293169161 cites W1993136476 @default.
• W4293169161 cites W1994278598 @default.
• W4293169161 cites W1998139623 @default.
• W4293169161 cites W2002380506 @default.
• W4293169161 cites W2004500886 @default.
• W4293169161 cites W2021948973 @default.
• W4293169161 cites W2034699053 @default.
• W4293169161 cites W2039551089 @default.
• W4293169161 cites W2042666718 @default.
• W4293169161 cites W2049520710 @default.
• W4293169161 cites W2049759608 @default.
• W4293169161 cites W2057711709 @default.
• W4293169161 cites W2059734331 @default.
• W4293169161 cites W2060865670 @default.
• W4293169161 cites W2063006927 @default.
• W4293169161 cites W2070389232 @default.
• W4293169161 cites W2075261488 @default.
• W4293169161 cites W2079350158 @default.
• W4293169161 cites W2087854601 @default.
• W4293169161 cites W2091254570 @default.
• W4293169161 cites W2096347191 @default.
• W4293169161 cites W2101208791 @default.
• W4293169161 cites W2123550299 @default.
• W4293169161 cites W2132608906 @default.
• W4293169161 cites W2134482053 @default.
• W4293169161 cites W2149204499 @default.
• W4293169161 cites W2159093669 @default.
• W4293169161 cites W2195358106 @default.
• W4293169161 cites W2298193523 @default.
• W4293169161 cites W2401484303 @default.
• W4293169161 cites W2412834561 @default.
• W4293169161 cites W2461540377 @default.
• W4293169161 cites W2615924632 @default.
• W4293169161 cites W2621803930 @default.
• W4293169161 cites W2747434737 @default.
• W4293169161 cites W2792504582 @default.
• W4293169161 cites W2793047625 @default.
• W4293169161 cites W2805845181 @default.
• W4293169161 cites W2807521334 @default.
• W4293169161 cites W2890169764 @default.
• W4293169161 cites W2891637410 @default.
• W4293169161 cites W2893366788 @default.
• W4293169161 cites W2951429011 @default.
• W4293169161 cites W2986206385 @default.
• W4293169161 cites W2998089939 @default.
• W4293169161 cites W3008275985 @default.
• W4293169161 cites W3033359651 @default.
• W4293169161 cites W3190136861 @default.
• W4293169161 cites W3193790330 @default.
• W4293169161 cites W4210929019 @default.
• W4293169161 cites W4220966507 @default.
• W4293169161 cites W4248180170 @default.
• W4293169161 doi "https://doi.org/10.3390/v14091844" @default.
• W4293169161 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36146649" @default.
• W4293169161 hasPublicationYear "2022" @default.
• W4293169161 type Work @default.
• W4293169161 citedByCount "2" @default.
• W4293169161 countsByYear W42931691612022 @default.
• W4293169161 crossrefType "journal-article" @default.
• W4293169161 hasAuthorship W4293169161A5003888491 @default.
• W4293169161 hasAuthorship W4293169161A5037873650 @default.
• W4293169161 hasAuthorship W4293169161A5045872492 @default.
• W4293169161 hasAuthorship W4293169161A5059119798 @default.
• W4293169161 hasAuthorship W4293169161A5061268334 @default.
• W4293169161 hasAuthorship W4293169161A5072866563 @default.
• W4293169161 hasBestOaLocation W42931691611 @default.
• W4293169161 hasConcept C104317684 @default.
• W4293169161 hasConcept C141231307 @default.
• W4293169161 hasConcept C159047783 @default.
• W4293169161 hasConcept C190743605 @default.
• W4293169161 hasConcept C2522874641 @default.
• W4293169161 hasConcept C2776408679 @default.
• W4293169161 hasConcept C2777510210 @default.
• W4293169161 hasConcept C2780847992 @default.
• W4293169161 hasConcept C54355233 @default.
• W4293169161 hasConcept C67705224 @default.
• W4293169161 hasConcept C86803240 @default.
• W4293169161 hasConceptScore W4293169161C104317684 @default.
• W4293169161 hasConceptScore W4293169161C141231307 @default.
• W4293169161 hasConceptScore W4293169161C159047783 @default.
• W4293169161 hasConceptScore W4293169161C190743605 @default.
• W4293169161 hasConceptScore W4293169161C2522874641 @default.
• W4293169161 hasConceptScore W4293169161C2776408679 @default.
• W4293169161 hasConceptScore W4293169161C2777510210 @default.
• W4293169161 hasConceptScore W4293169161C2780847992 @default.

• next