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- W4293231208 abstract "Introduction and aims: Women with a septate uterus have an increased risk of infertility and impair outcomes. Hysteroscopic metroplasty is a well-described procedure. The need for metroplasty is however controversial. A recent study concluded that metroplasty didn’t improve reproductive outcomes and lead to less chance of ongoing pregnancy than expectant management. Aim of this study is then to evaluate reproductive outcomes and risks of hysteroscopic metroplasty in women of reproductive age. Methods: We performed a retrospective bicentric study in the gynaecologic unit of two teaching hospitals with expertise in hysteroscopy. Consecutive women who underwent hysteroscopic metroplasty between 2009 and 2019 were included. Pregnancy outcomes were compared before and after hysteroscopic metroplasty. Results and discussion: A total of 519 women were included; 170 were lost to follow-up and 85 didn’t try to get pregnant after surgery. Among the 107 women with history of infertility, 74/107 women (69.2%) got pregnant after metroplasty (41.9% after assisted reproductive technology (31/74)) and 77% of them had live birth (57/74). For pregnancy loss, the rate of women with at least one pregnancy loss was 44.7% (118/264) before versus 14.8% after metroplasty (39/264). For live birth, 13.6% of women (36/264) had a live birth before versus 80.6% (174/264) after. One uterine rupture at the subsequent pregnancy was reported with a per-partum death of the child (0.4%). Our results are concordant with previous published studies. The before/after design is not optimal but it is questionable whether it would be possible to perform a randomized trial today. Conclusion: Hysteroscopic metroplasty in women of reproductive age with a septate uterus seems to improve reproductive outcomes." @default.
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- W4293231208 date "2022-03-01" @default.
- W4293231208 modified "2023-09-26" @default.
- W4293231208 title "352 Hysteroscopic metroplasty for septate uterus: A retrospective bicentric study involving 519 women" @default.
- W4293231208 doi "https://doi.org/10.1016/j.ejogrb.2021.11.319" @default.
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