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- W4293256751 abstract "Familial hypercholesterolemia (FH), an autosomal co-dominant disease affecting overall 1:250–300 people, causes early atherosclerotic cardiovascular disease (ASCVD) and mortality [1]. Even recognizing that the risk attributable to FH is higher than the one of the general population [2], a fact seen even among those with severe hypercholesterolemia (i.e., LDL-cholesterol > 190 mg/dL) [3], the onset of ASCVD is heterogenous among people with the disease [1,4–7]. This is especially seen in contemporary heterozygous FH populations in use of statin therapy [2,7–9]." @default.
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- W4293256751 date "2022-10-01" @default.
- W4293256751 modified "2023-09-27" @default.
- W4293256751 title "Difficulties in gauging atherosclerotic cardiovascular disease risk heterogeneity in familial hypercholesterolemia" @default.
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- W4293256751 doi "https://doi.org/10.1016/j.atherosclerosis.2022.08.006" @default.
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