Matches in SemOpenAlex for { <https://semopenalex.org/work/W4293318461> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W4293318461 endingPage "227" @default.
- W4293318461 startingPage "216" @default.
- W4293318461 abstract "Acute infectious mononucleosis (AIM) is associated with Epstein-Barr virus (EBV) infection. We explored molecular mechanisms regarding the expression of CD8+T cells in convalescence stage (CONV). Differentially expressed genes (DEGs) were identified by analyzing GEO expression profiles. Subsequently, Gene Set Enrichment Analysis (GSEA), Protein-Protein Interactions (PPI) network, and gene-micro RNAs networks were used to identify hub genes and associated pathways. GSEA provided evidence that the top 3 gene sets in GSEA were all related to integrins. We identified ten hub genes in the PPI network and DGIdb was applied to predict potential targets that might reverse the expression of hub genes. Our study enhances a mechanistic understanding of the CD8+T cells expansion in acute EBV infection and provides potential treatment targets for further research. Keywords: acute infectious mononucleosis; bioinformatics; CD8+T cells; differentially expressed genes; EBV." @default.
- W4293318461 created "2022-08-27" @default.
- W4293318461 creator A5034266315 @default.
- W4293318461 creator A5063517725 @default.
- W4293318461 creator A5064169457 @default.
- W4293318461 creator A5066796679 @default.
- W4293318461 date "2022-01-01" @default.
- W4293318461 modified "2023-09-30" @default.
- W4293318461 title "A gene expression signature that correlates with CD8+T cell expansion in acute Epstein-Barr virus infection" @default.
- W4293318461 doi "https://doi.org/10.4149/av_2022_303" @default.
- W4293318461 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36029087" @default.
- W4293318461 hasPublicationYear "2022" @default.
- W4293318461 type Work @default.
- W4293318461 citedByCount "0" @default.
- W4293318461 crossrefType "journal-article" @default.
- W4293318461 hasAuthorship W4293318461A5034266315 @default.
- W4293318461 hasAuthorship W4293318461A5063517725 @default.
- W4293318461 hasAuthorship W4293318461A5064169457 @default.
- W4293318461 hasAuthorship W4293318461A5066796679 @default.
- W4293318461 hasBestOaLocation W42933184611 @default.
- W4293318461 hasConcept C104317684 @default.
- W4293318461 hasConcept C141071460 @default.
- W4293318461 hasConcept C150194340 @default.
- W4293318461 hasConcept C159047783 @default.
- W4293318461 hasConcept C162317418 @default.
- W4293318461 hasConcept C167672396 @default.
- W4293318461 hasConcept C18431079 @default.
- W4293318461 hasConcept C203014093 @default.
- W4293318461 hasConcept C2522874641 @default.
- W4293318461 hasConcept C2776129502 @default.
- W4293318461 hasConcept C2777945365 @default.
- W4293318461 hasConcept C2780494569 @default.
- W4293318461 hasConcept C2781375147 @default.
- W4293318461 hasConcept C54355233 @default.
- W4293318461 hasConcept C71924100 @default.
- W4293318461 hasConcept C86803240 @default.
- W4293318461 hasConcept C8891405 @default.
- W4293318461 hasConceptScore W4293318461C104317684 @default.
- W4293318461 hasConceptScore W4293318461C141071460 @default.
- W4293318461 hasConceptScore W4293318461C150194340 @default.
- W4293318461 hasConceptScore W4293318461C159047783 @default.
- W4293318461 hasConceptScore W4293318461C162317418 @default.
- W4293318461 hasConceptScore W4293318461C167672396 @default.
- W4293318461 hasConceptScore W4293318461C18431079 @default.
- W4293318461 hasConceptScore W4293318461C203014093 @default.
- W4293318461 hasConceptScore W4293318461C2522874641 @default.
- W4293318461 hasConceptScore W4293318461C2776129502 @default.
- W4293318461 hasConceptScore W4293318461C2777945365 @default.
- W4293318461 hasConceptScore W4293318461C2780494569 @default.
- W4293318461 hasConceptScore W4293318461C2781375147 @default.
- W4293318461 hasConceptScore W4293318461C54355233 @default.
- W4293318461 hasConceptScore W4293318461C71924100 @default.
- W4293318461 hasConceptScore W4293318461C86803240 @default.
- W4293318461 hasConceptScore W4293318461C8891405 @default.
- W4293318461 hasIssue "03" @default.
- W4293318461 hasLocation W42933184611 @default.
- W4293318461 hasLocation W42933184612 @default.
- W4293318461 hasOpenAccess W4293318461 @default.
- W4293318461 hasPrimaryLocation W42933184611 @default.
- W4293318461 hasRelatedWork W1963858099 @default.
- W4293318461 hasRelatedWork W2025227319 @default.
- W4293318461 hasRelatedWork W2107300305 @default.
- W4293318461 hasRelatedWork W2128356179 @default.
- W4293318461 hasRelatedWork W2181772832 @default.
- W4293318461 hasRelatedWork W2340857673 @default.
- W4293318461 hasRelatedWork W2400528911 @default.
- W4293318461 hasRelatedWork W2461720205 @default.
- W4293318461 hasRelatedWork W2567931202 @default.
- W4293318461 hasRelatedWork W2973339054 @default.
- W4293318461 hasVolume "66" @default.
- W4293318461 isParatext "false" @default.
- W4293318461 isRetracted "false" @default.
- W4293318461 workType "article" @default.