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- W4293375771 endingPage "445" @default.
- W4293375771 startingPage "435" @default.
- W4293375771 abstract "MicroRNAs are small RNAs with ability to attach to the large number of RNA that regulate gene expression on post-transcriptional level via inhibition or degradation of specific mRNAs. MiRNAs in cells are the primary regulators of functions such as cell growth, differentiation, and apoptosis and considerably influence cell function. The expression levels of microRNAs change in human diseases, including cancer. These changes highlight their essential role in cancer pathogenesis. Ubiquitous irregular expression profiles of miRNAs have been detected in various human cancers using genome-wide identification techniques, which are emerging as novel diagnostic and prognostic cancer biomarkers of high specificity and sensitivity. The measurable miRNAs with enhanced stability in blood, tissues, and other body fluids provide a comprehensive source of miRNA-dependent biomarkers for human cancers. The leading role of miRNAs as potential biomarkers in human cancers is discussed in this article. In addition, the interests and difficulties of miRNAs as biomarkers have been explored." @default.
- W4293375771 created "2022-08-28" @default.
- W4293375771 creator A5001828364 @default.
- W4293375771 creator A5018530517 @default.
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- W4293375771 creator A5076497908 @default.
- W4293375771 creator A5083823112 @default.
- W4293375771 creator A5084471562 @default.
- W4293375771 date "2022-07-02" @default.
- W4293375771 modified "2023-09-30" @default.
- W4293375771 title "MicroRNAs as Targets for Cancer Diagnosis: Interests and Limitations" @default.
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