FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4293388049> ?p ?o ?g. }

• W4293388049 endingPage "1254" @default.
• W4293388049 startingPage "1241" @default.
• W4293388049 abstract "What is the central question of this study? Ischaemic preconditioning is a novel pre-exercise priming strategy. We asked whether ischaemic preconditioning would alter mitochondrial respiratory function and pulmonary oxygen uptake kinetics and improve severe-intensity exercise performance. What is the main finding and its importance? Ischaemic preconditioning expedited overall pulmonary oxygen uptake kinetics and appeared to prevent an increase in leak respiration, proportional to maximal electron transfer system and ADP-stimulated respiration, that was evoked by severe-intensity exercise in sham-control conditions. However, severe-intensity exercise performance was not improved. The results do not support ischaemic preconditioning as a pre-exercise strategy to improve exercise performance in recreationally active participants.We examined the effect of ischaemic preconditioning (IPC) on severe-intensity exercise performance, pulmonary oxygen uptake ( V̇O2${dot V_{{{rm{O}}_{rm{2}}}}}$ ) kinetics, skeletal muscle oxygenation (muscle tissue O2 saturation index) and mitochondrial respiration. Eight men underwent contralateral IPC (4 × 5 min at 220 mmHg) or sham-control (SHAM; 20 mmHg) before performing a cycling time-to-exhaustion test (92% maximum aerobic power). Muscle (vastus lateralis) biopsies were obtained before IPC or SHAM and ∼1.5 min postexercise. The time to exhaustion did not differ between SHAM and IPC (249 ± 37 vs. 240 ± 32 s; P = 0.62). Pre- and postexercise ADP-stimulated (P) and maximal (E) mitochondrial respiration through protein complexes (C) I, II and IV did not differ (P > 0.05). Complex I leak respiration was greater postexercise compared with baseline in SHAM, but not in IPC, when normalized to wet mass (P = 0.01 vs. P = 0.19), mitochondrial content (citrate synthase activity, P = 0.003 vs. P = 0.16; CI+IIP, P = 0.03 vs. P = 0.23) and expressed relative to P (P = 0.006 vs. P = 0.30) and E (P = 0.004 vs. P = 0.26). The V̇O2${dot V_{{{rm{O}}_{rm{2}}}}}$ mean response time was faster (51.3 ± 15.5 vs. 63.7 ± 14.5 s; P = 0.003), with a smaller slow component (270 ± 105 vs. 377 ± 188 ml min-1 ; P = 0.03), in IPC compared with SHAM. The muscle tissue O2 saturation index did not differ between trials (P > 0.05). Ischaemic preconditioning expedited V̇O2${dot V_{{{rm{O}}_{rm{2}}}}}$ kinetics and appeared to prevent an increase in leak respiration through CI, when expressed proportional to E and P evoked by severe-intensity exercise, but did not improve exercise performance." @default.
• W4293388049 created "2022-08-28" @default.
• W4293388049 creator A5004664195 @default.
• W4293388049 creator A5018933240 @default.
• W4293388049 creator A5027978067 @default.
• W4293388049 creator A5074638228 @default.
• W4293388049 date "2022-09-13" @default.
• W4293388049 modified "2023-09-27" @default.
• W4293388049 title "Ischaemic preconditioning blunts exercise‐induced mitochondrial dysfunction, speeds oxygen uptake kinetics but does not alter severe‐intensity exercise capacity" @default.
• W4293388049 cites W169575131 @default.
• W4293388049 cites W1751998231 @default.
• W4293388049 cites W1899906888 @default.
• W4293388049 cites W1902298727 @default.
• W4293388049 cites W191921287 @default.
• W4293388049 cites W1965354369 @default.
• W4293388049 cites W1998862257 @default.
• W4293388049 cites W2005362740 @default.
• W4293388049 cites W2029051533 @default.
• W4293388049 cites W2050008654 @default.
• W4293388049 cites W2078416377 @default.
• W4293388049 cites W2087295665 @default.
• W4293388049 cites W2088280369 @default.
• W4293388049 cites W2091463581 @default.
• W4293388049 cites W2097817702 @default.
• W4293388049 cites W2105580366 @default.
• W4293388049 cites W2125266039 @default.
• W4293388049 cites W2128809832 @default.
• W4293388049 cites W2133244276 @default.
• W4293388049 cites W2134245112 @default.
• W4293388049 cites W2138400727 @default.
• W4293388049 cites W2138689154 @default.
• W4293388049 cites W2142616064 @default.
• W4293388049 cites W2143588920 @default.
• W4293388049 cites W2146217294 @default.
• W4293388049 cites W2163344162 @default.
• W4293388049 cites W2166552952 @default.
• W4293388049 cites W2169438140 @default.
• W4293388049 cites W2172256184 @default.
• W4293388049 cites W2185160981 @default.
• W4293388049 cites W2195185194 @default.
• W4293388049 cites W2258080788 @default.
• W4293388049 cites W2260205858 @default.
• W4293388049 cites W2284845240 @default.
• W4293388049 cites W2317342304 @default.
• W4293388049 cites W2324950221 @default.
• W4293388049 cites W2395314412 @default.
• W4293388049 cites W2465565601 @default.
• W4293388049 cites W2562427369 @default.
• W4293388049 cites W2773618682 @default.
• W4293388049 cites W2792481450 @default.
• W4293388049 cites W2804261166 @default.
• W4293388049 cites W2887129624 @default.
• W4293388049 cites W2891972825 @default.
• W4293388049 cites W2898180500 @default.
• W4293388049 cites W2901106507 @default.
• W4293388049 cites W3200146768 @default.
• W4293388049 cites W4206640013 @default.
• W4293388049 cites W4241613218 @default.
• W4293388049 cites W4250904480 @default.
• W4293388049 cites W4256272833 @default.
• W4293388049 cites W4293388049 @default.
• W4293388049 doi "https://doi.org/10.1113/ep090264" @default.
• W4293388049 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36030522" @default.
• W4293388049 hasPublicationYear "2022" @default.
• W4293388049 type Work @default.
• W4293388049 citedByCount "2" @default.
• W4293388049 countsByYear W42933880492022 @default.
• W4293388049 countsByYear W42933880492023 @default.
• W4293388049 crossrefType "journal-article" @default.
• W4293388049 hasAuthorship W4293388049A5004664195 @default.
• W4293388049 hasAuthorship W4293388049A5018933240 @default.
• W4293388049 hasAuthorship W4293388049A5027978067 @default.
• W4293388049 hasAuthorship W4293388049A5074638228 @default.
• W4293388049 hasBestOaLocation W42933880491 @default.
• W4293388049 hasConcept C105702510 @default.
• W4293388049 hasConcept C126322002 @default.
• W4293388049 hasConcept C164705383 @default.
• W4293388049 hasConcept C182215343 @default.
• W4293388049 hasConcept C185592680 @default.
• W4293388049 hasConcept C196310339 @default.
• W4293388049 hasConcept C2776294035 @default.
• W4293388049 hasConcept C2776811442 @default.
• W4293388049 hasConcept C2777953023 @default.
• W4293388049 hasConcept C2779311647 @default.
• W4293388049 hasConcept C2779959927 @default.
• W4293388049 hasConcept C2992422156 @default.
• W4293388049 hasConcept C541997718 @default.
• W4293388049 hasConcept C71924100 @default.
• W4293388049 hasConcept C84393581 @default.
• W4293388049 hasConceptScore W4293388049C105702510 @default.
• W4293388049 hasConceptScore W4293388049C126322002 @default.
• W4293388049 hasConceptScore W4293388049C164705383 @default.
• W4293388049 hasConceptScore W4293388049C182215343 @default.
• W4293388049 hasConceptScore W4293388049C185592680 @default.
• W4293388049 hasConceptScore W4293388049C196310339 @default.
• W4293388049 hasConceptScore W4293388049C2776294035 @default.
• W4293388049 hasConceptScore W4293388049C2776811442 @default.
• W4293388049 hasConceptScore W4293388049C2777953023 @default.

• next