Matches in SemOpenAlex for { <https://semopenalex.org/work/W4293388294> ?p ?o ?g. }
- W4293388294 endingPage "114808" @default.
- W4293388294 startingPage "114808" @default.
- W4293388294 abstract "The insular cortex plays a critical role in reward circuitry involved with drug craving in substance use disorders. This study aimed to investigate whether opioid use disorder exhibit functional alterations in the insular circuitry after abstinence. Sixty-one opioid use disorder underwent resting-state and 3D-T1-weighted magnetic resonance imaging and completed craving questionnaires at baseline and after 8 months of abstinence. Changes in resting-state functional connectivity in the insular cortex and their correlations with craving were analyzed. Craving was reduced at follow-up compared with baseline. Compared with that at baseline, there was significantly increased resting-state functional connectivity between the right insular cortex and the superior frontal gyrus/anterior cingulate gyrus (family-wise error corrected) at follow-up. Changes in the functional connectivity of the right dorsal anterior insula/posterior insula with the bilateral superior frontal gyrus were negatively correlated with changes in craving. Our results demonstrated the presence of changes in functional connectivity of the insula in opioid use disorder after protracted abstinence, providing novel evidence of a correlation between craving changes and changes in the neurocircuitry of insular cortex subdivision after abstinence. This study reveals the possibility of neuroplasticity after protracted abstinence, providing insight for future abstinence therapies and rehabilitation procedures for patients with substance use disorders." @default.
- W4293388294 created "2022-08-28" @default.
- W4293388294 creator A5029311630 @default.
- W4293388294 creator A5032173749 @default.
- W4293388294 creator A5039490628 @default.
- W4293388294 creator A5042655080 @default.
- W4293388294 creator A5044655400 @default.
- W4293388294 creator A5047051172 @default.
- W4293388294 creator A5053204257 @default.
- W4293388294 creator A5062114297 @default.
- W4293388294 creator A5071672663 @default.
- W4293388294 creator A5080616533 @default.
- W4293388294 creator A5083841170 @default.
- W4293388294 date "2022-11-01" @default.
- W4293388294 modified "2023-10-18" @default.
- W4293388294 title "Longitudinal resting-state functional connectivity changes in the insular subdivisions of abstinent individuals with opioid use disorder" @default.
- W4293388294 cites W146572136 @default.
- W4293388294 cites W1525850716 @default.
- W4293388294 cites W1970414462 @default.
- W4293388294 cites W1985552279 @default.
- W4293388294 cites W1994795469 @default.
- W4293388294 cites W1997839536 @default.
- W4293388294 cites W2011693288 @default.
- W4293388294 cites W2036074427 @default.
- W4293388294 cites W2050597556 @default.
- W4293388294 cites W2057600612 @default.
- W4293388294 cites W2082357982 @default.
- W4293388294 cites W2097716051 @default.
- W4293388294 cites W2102139723 @default.
- W4293388294 cites W2113737964 @default.
- W4293388294 cites W2118515954 @default.
- W4293388294 cites W2123705561 @default.
- W4293388294 cites W2132270675 @default.
- W4293388294 cites W2164081174 @default.
- W4293388294 cites W2296674052 @default.
- W4293388294 cites W2643238975 @default.
- W4293388294 cites W2765507708 @default.
- W4293388294 cites W2767727317 @default.
- W4293388294 cites W2793350897 @default.
- W4293388294 cites W2980348977 @default.
- W4293388294 cites W3044203763 @default.
- W4293388294 cites W3089050333 @default.
- W4293388294 cites W3123969857 @default.
- W4293388294 cites W3124039529 @default.
- W4293388294 cites W3163016435 @default.
- W4293388294 cites W3164355366 @default.
- W4293388294 cites W3192512809 @default.
- W4293388294 cites W3194069891 @default.
- W4293388294 cites W3205836976 @default.
- W4293388294 cites W4220841472 @default.
- W4293388294 cites W4221093504 @default.
- W4293388294 cites W4224528528 @default.
- W4293388294 cites W4225460817 @default.
- W4293388294 cites W4225540199 @default.
- W4293388294 cites W4225665748 @default.
- W4293388294 cites W4229005477 @default.
- W4293388294 cites W882810539 @default.
- W4293388294 cites W2939664250 @default.
- W4293388294 doi "https://doi.org/10.1016/j.psychres.2022.114808" @default.
- W4293388294 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36055065" @default.
- W4293388294 hasPublicationYear "2022" @default.
- W4293388294 type Work @default.
- W4293388294 citedByCount "0" @default.
- W4293388294 crossrefType "journal-article" @default.
- W4293388294 hasAuthorship W4293388294A5029311630 @default.
- W4293388294 hasAuthorship W4293388294A5032173749 @default.
- W4293388294 hasAuthorship W4293388294A5039490628 @default.
- W4293388294 hasAuthorship W4293388294A5042655080 @default.
- W4293388294 hasAuthorship W4293388294A5044655400 @default.
- W4293388294 hasAuthorship W4293388294A5047051172 @default.
- W4293388294 hasAuthorship W4293388294A5053204257 @default.
- W4293388294 hasAuthorship W4293388294A5062114297 @default.
- W4293388294 hasAuthorship W4293388294A5071672663 @default.
- W4293388294 hasAuthorship W4293388294A5080616533 @default.
- W4293388294 hasAuthorship W4293388294A5083841170 @default.
- W4293388294 hasBestOaLocation W42933882941 @default.
- W4293388294 hasConcept C104996578 @default.
- W4293388294 hasConcept C118552586 @default.
- W4293388294 hasConcept C126322002 @default.
- W4293388294 hasConcept C15744967 @default.
- W4293388294 hasConcept C169760540 @default.
- W4293388294 hasConcept C169900460 @default.
- W4293388294 hasConcept C170493617 @default.
- W4293388294 hasConcept C2778402161 @default.
- W4293388294 hasConcept C2779226451 @default.
- W4293388294 hasConcept C2779418921 @default.
- W4293388294 hasConcept C2779541405 @default.
- W4293388294 hasConcept C2779991468 @default.
- W4293388294 hasConcept C2780539906 @default.
- W4293388294 hasConcept C2780687700 @default.
- W4293388294 hasConcept C2781063702 @default.
- W4293388294 hasConcept C2781300654 @default.
- W4293388294 hasConcept C2781449700 @default.
- W4293388294 hasConcept C48856860 @default.
- W4293388294 hasConcept C66324658 @default.
- W4293388294 hasConcept C71924100 @default.
- W4293388294 hasConceptScore W4293388294C104996578 @default.
- W4293388294 hasConceptScore W4293388294C118552586 @default.