Matches in SemOpenAlex for { <https://semopenalex.org/work/W4293413672> ?p ?o ?g. }
- W4293413672 endingPage "1188" @default.
- W4293413672 startingPage "1188" @default.
- W4293413672 abstract "In this study, we examined the protective effects of curcumin against the AFB1-induced immune response of and pathological changes in broilers. Histopathology examinations showed that at day 28, AFB1 (5 mg/kg) exposure leads to severe histological changes in the spleen, thymus and bursa of Fabricius with a decrease in the number and karyoplasmic area ratio of plasma cells. Curcumin alleviated the AFB1-induced immune organs’ damage as well as the changes in plasma cells in a dose-dependent manner. RT-PCR data showed that AFB1 significantly downregulated the IL-2 and IFN-γ mRNA expression levels in the thymus, spleen and bursa of Fabricius. However, curcumin supplementation improved the AFB1-induced immune organs’ damage via upregulated cytokines’ expression. Intriguingly, similar trends were noticed in abnormal morphological changes and the immune response at day 35 after the withdrawal of AFB1 and curcumin from the diet, suggesting the protective effects and immunomodulatory function against AFB1 in broilers. The current study provides a scientific experimental basis for the application of curcumin as a therapeutic drug or additive in animal husbandry productive practice." @default.
- W4293413672 created "2022-08-29" @default.
- W4293413672 creator A5021334632 @default.
- W4293413672 creator A5026457044 @default.
- W4293413672 creator A5028476395 @default.
- W4293413672 creator A5030216084 @default.
- W4293413672 creator A5034169829 @default.
- W4293413672 creator A5043422829 @default.
- W4293413672 creator A5080690870 @default.
- W4293413672 date "2022-08-26" @default.
- W4293413672 modified "2023-09-26" @default.
- W4293413672 title "Effect of Curcumin as Feed Supplement on Immune Response and Pathological Changes of Broilers Exposed to Aflatoxin B1" @default.
- W4293413672 cites W1965734808 @default.
- W4293413672 cites W1974410756 @default.
- W4293413672 cites W1977191081 @default.
- W4293413672 cites W1985877783 @default.
- W4293413672 cites W2001748660 @default.
- W4293413672 cites W2012028309 @default.
- W4293413672 cites W2013618934 @default.
- W4293413672 cites W2016112814 @default.
- W4293413672 cites W2017060577 @default.
- W4293413672 cites W2026927028 @default.
- W4293413672 cites W2028297201 @default.
- W4293413672 cites W2034754026 @default.
- W4293413672 cites W2035661016 @default.
- W4293413672 cites W2047373024 @default.
- W4293413672 cites W2048453531 @default.
- W4293413672 cites W2084754368 @default.
- W4293413672 cites W2106523583 @default.
- W4293413672 cites W2107277218 @default.
- W4293413672 cites W2129482886 @default.
- W4293413672 cites W2131748930 @default.
- W4293413672 cites W2131767068 @default.
- W4293413672 cites W2141280116 @default.
- W4293413672 cites W2145004862 @default.
- W4293413672 cites W2145299221 @default.
- W4293413672 cites W2167017590 @default.
- W4293413672 cites W2192080449 @default.
- W4293413672 cites W2297548931 @default.
- W4293413672 cites W2302954221 @default.
- W4293413672 cites W2303243662 @default.
- W4293413672 cites W2327361841 @default.
- W4293413672 cites W2331201236 @default.
- W4293413672 cites W2420706738 @default.
- W4293413672 cites W2495430411 @default.
- W4293413672 cites W2556148229 @default.
- W4293413672 cites W2562428411 @default.
- W4293413672 cites W2595445717 @default.
- W4293413672 cites W2603994490 @default.
- W4293413672 cites W2729208408 @default.
- W4293413672 cites W2738212354 @default.
- W4293413672 cites W2765276480 @default.
- W4293413672 cites W2782420703 @default.
- W4293413672 cites W2792096245 @default.
- W4293413672 cites W2792596738 @default.
- W4293413672 cites W2800681712 @default.
- W4293413672 cites W2803521803 @default.
- W4293413672 cites W2811341285 @default.
- W4293413672 cites W2853958505 @default.
- W4293413672 cites W2899301437 @default.
- W4293413672 cites W2917412606 @default.
- W4293413672 cites W2922212539 @default.
- W4293413672 cites W2944217339 @default.
- W4293413672 cites W3178222235 @default.
- W4293413672 cites W3182457501 @default.
- W4293413672 cites W4210538319 @default.
- W4293413672 cites W4220900289 @default.
- W4293413672 doi "https://doi.org/10.3390/biom12091188" @default.
- W4293413672 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36139027" @default.
- W4293413672 hasPublicationYear "2022" @default.
- W4293413672 type Work @default.
- W4293413672 citedByCount "1" @default.
- W4293413672 countsByYear W42934136722023 @default.
- W4293413672 crossrefType "journal-article" @default.
- W4293413672 hasAuthorship W4293413672A5021334632 @default.
- W4293413672 hasAuthorship W4293413672A5026457044 @default.
- W4293413672 hasAuthorship W4293413672A5028476395 @default.
- W4293413672 hasAuthorship W4293413672A5030216084 @default.
- W4293413672 hasAuthorship W4293413672A5034169829 @default.
- W4293413672 hasAuthorship W4293413672A5043422829 @default.
- W4293413672 hasAuthorship W4293413672A5080690870 @default.
- W4293413672 hasBestOaLocation W42934136721 @default.
- W4293413672 hasConcept C142724271 @default.
- W4293413672 hasConcept C150903083 @default.
- W4293413672 hasConcept C159674089 @default.
- W4293413672 hasConcept C196978929 @default.
- W4293413672 hasConcept C203014093 @default.
- W4293413672 hasConcept C2778250585 @default.
- W4293413672 hasConcept C2780931953 @default.
- W4293413672 hasConcept C40758303 @default.
- W4293413672 hasConcept C544855455 @default.
- W4293413672 hasConcept C71924100 @default.
- W4293413672 hasConcept C86803240 @default.
- W4293413672 hasConcept C8891405 @default.
- W4293413672 hasConcept C98274493 @default.
- W4293413672 hasConceptScore W4293413672C142724271 @default.
- W4293413672 hasConceptScore W4293413672C150903083 @default.
- W4293413672 hasConceptScore W4293413672C159674089 @default.