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• W4293473440 endingPage "110693" @default.
• W4293473440 startingPage "110693" @default.
• W4293473440 abstract "In this paper, oxazolepyridine and coumarin units were combined to prepare cell membrane fluorescent probe (PM-A) through aldol condensation reaction. PM-A had long wavelength emission (665–739 nm), high molar extinction coefficient (around 3.14 × 104 M−1cm−1) and large Stokes shift (150–219 nm). The photo-stability test showed that PM-A had a high relative residual absorption (93%) after 6 h of continuous illumination. In addition, the supramolecular interaction between PM-A and β-cyclodextrin was evaluated and applied to cell imaging. Probe PM-A had no fluorescence in water, but had obvious fluorescence signal in β-cyclodextrin solution. With the addition of β-cyclodextrin (0–800 eq), the fluorescence quantum yield of PM-A increased from 0% to 45%. Laser confocal experiments showed that when only PM-A was added, the probe concentration needed to be 15 μM to image the cell membrane obviously. In sharp contrast, with the help of β-cyclodextrin solution, the concentration of probe PM-A only needed 0.5 μM to quick and high specificity image cell membranes. Moreover, PM-A had high photo-bleaching resistance and long retention time after adding β-cyclodextrin. These excellent properties of PM-A were of great significance to the study of cell membrane." @default.
• W4293473440 created "2022-08-29" @default.
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• W4293473440 date "2022-11-01" @default.
• W4293473440 modified "2023-10-16" @default.
• W4293473440 title "Fluorescence enhancement of near infrared cell membrane probe by β-cyclodextrin supramolecular interaction" @default.
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• W4293473440 doi "https://doi.org/10.1016/j.dyepig.2022.110693" @default.
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