Matches in SemOpenAlex for { <https://semopenalex.org/work/W4293491581> ?p ?o ?g. }
- W4293491581 endingPage "100563" @default.
- W4293491581 startingPage "100563" @default.
- W4293491581 abstract "Anterior thalamic deep brain stimulation (DBS) is a palliative treatment that may be considered in patients with drug resistant epilepsy (DRE) that fail treatment with vagus nerve stimulation (VNS). Combining VNS and DBS treatment is a therapeutic approach rarely reported. This single center observational study aims to describe response to DBS treatment in 11 epilepsy patients resistant to medications and VNS. Patients either had inactivated VNS (DBS only) or were treated with simultaneous DBS and VNS (DBS-VNS). Focal impaired awareness (FIA) and most disabling seizure rates were examined pre-DBS implantation, 3 months following implantation, and last follow up. Overall, a decrease in FIA (47.0 ± 30.7 %, p = 0.02) and most disabling seizure rate (54.8 ± 34.2 %, p = 0.03) was seen at last follow-up (average follow-up 28.5 ± 13.5 months). Eight of 11 patients were DBS responders (most disabling seizure rate reduction above 50%). No difference in seizure control was found between seven DBS only and four DBS-VNS patients. Our results argue that patients who have failed antiseizure medication and VNS therapies, could benefit from better seizure control if treated with adjunctive DBS. Larger prospective studies are needed to assess the efficacy and safety of combined neurostimulation treatments in DRE." @default.
- W4293491581 created "2022-08-29" @default.
- W4293491581 creator A5002834753 @default.
- W4293491581 creator A5003922053 @default.
- W4293491581 creator A5006284340 @default.
- W4293491581 creator A5042913367 @default.
- W4293491581 date "2022-01-01" @default.
- W4293491581 modified "2023-10-16" @default.
- W4293491581 title "Anterior thalamic deep brain stimulation in epilepsy patients refractory to vagus nerve stimulation: A single center observational study" @default.
- W4293491581 cites W1541374638 @default.
- W4293491581 cites W1553285561 @default.
- W4293491581 cites W1723529628 @default.
- W4293491581 cites W1920418959 @default.
- W4293491581 cites W1969697630 @default.
- W4293491581 cites W1973616821 @default.
- W4293491581 cites W1991623258 @default.
- W4293491581 cites W1998429612 @default.
- W4293491581 cites W2002396969 @default.
- W4293491581 cites W2008953662 @default.
- W4293491581 cites W2034471764 @default.
- W4293491581 cites W2053258270 @default.
- W4293491581 cites W2059497817 @default.
- W4293491581 cites W2071334323 @default.
- W4293491581 cites W2074386170 @default.
- W4293491581 cites W2078790407 @default.
- W4293491581 cites W2119483507 @default.
- W4293491581 cites W2135629133 @default.
- W4293491581 cites W2158334924 @default.
- W4293491581 cites W2602582143 @default.
- W4293491581 cites W2737966001 @default.
- W4293491581 cites W2792435683 @default.
- W4293491581 cites W2794135937 @default.
- W4293491581 cites W2800940575 @default.
- W4293491581 cites W2871023201 @default.
- W4293491581 cites W2974045819 @default.
- W4293491581 cites W3026601748 @default.
- W4293491581 cites W3091781539 @default.
- W4293491581 cites W3192365860 @default.
- W4293491581 cites W3196379058 @default.
- W4293491581 cites W3211542128 @default.
- W4293491581 cites W4212875008 @default.
- W4293491581 cites W4282026709 @default.
- W4293491581 doi "https://doi.org/10.1016/j.ebr.2022.100563" @default.
- W4293491581 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36119948" @default.
- W4293491581 hasPublicationYear "2022" @default.
- W4293491581 type Work @default.
- W4293491581 citedByCount "2" @default.
- W4293491581 countsByYear W42934915812023 @default.
- W4293491581 crossrefType "journal-article" @default.
- W4293491581 hasAuthorship W4293491581A5002834753 @default.
- W4293491581 hasAuthorship W4293491581A5003922053 @default.
- W4293491581 hasAuthorship W4293491581A5006284340 @default.
- W4293491581 hasAuthorship W4293491581A5042913367 @default.
- W4293491581 hasBestOaLocation W42934915811 @default.
- W4293491581 hasConcept C118552586 @default.
- W4293491581 hasConcept C121332964 @default.
- W4293491581 hasConcept C126322002 @default.
- W4293491581 hasConcept C142424586 @default.
- W4293491581 hasConcept C23131810 @default.
- W4293491581 hasConcept C24998067 @default.
- W4293491581 hasConcept C2776443511 @default.
- W4293491581 hasConcept C2778186239 @default.
- W4293491581 hasConcept C2778542668 @default.
- W4293491581 hasConcept C2779134260 @default.
- W4293491581 hasConcept C2779734285 @default.
- W4293491581 hasConcept C2780087125 @default.
- W4293491581 hasConcept C2781404750 @default.
- W4293491581 hasConcept C2910833928 @default.
- W4293491581 hasConcept C42219234 @default.
- W4293491581 hasConcept C71924100 @default.
- W4293491581 hasConcept C87355193 @default.
- W4293491581 hasConceptScore W4293491581C118552586 @default.
- W4293491581 hasConceptScore W4293491581C121332964 @default.
- W4293491581 hasConceptScore W4293491581C126322002 @default.
- W4293491581 hasConceptScore W4293491581C142424586 @default.
- W4293491581 hasConceptScore W4293491581C23131810 @default.
- W4293491581 hasConceptScore W4293491581C24998067 @default.
- W4293491581 hasConceptScore W4293491581C2776443511 @default.
- W4293491581 hasConceptScore W4293491581C2778186239 @default.
- W4293491581 hasConceptScore W4293491581C2778542668 @default.
- W4293491581 hasConceptScore W4293491581C2779134260 @default.
- W4293491581 hasConceptScore W4293491581C2779734285 @default.
- W4293491581 hasConceptScore W4293491581C2780087125 @default.
- W4293491581 hasConceptScore W4293491581C2781404750 @default.
- W4293491581 hasConceptScore W4293491581C2910833928 @default.
- W4293491581 hasConceptScore W4293491581C42219234 @default.
- W4293491581 hasConceptScore W4293491581C71924100 @default.
- W4293491581 hasConceptScore W4293491581C87355193 @default.
- W4293491581 hasLocation W42934915811 @default.
- W4293491581 hasLocation W42934915812 @default.
- W4293491581 hasLocation W42934915813 @default.
- W4293491581 hasLocation W42934915814 @default.
- W4293491581 hasOpenAccess W4293491581 @default.
- W4293491581 hasPrimaryLocation W42934915811 @default.
- W4293491581 hasRelatedWork W1962086062 @default.
- W4293491581 hasRelatedWork W2030434698 @default.
- W4293491581 hasRelatedWork W2059972168 @default.
- W4293491581 hasRelatedWork W2082956324 @default.