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• W4293496876 abstract "<h3>Importance</h3> Cold, flu, and immunity dietary supplement product sales have skyrocketed since the start of the COVID-19 pandemic. Supporting or boosting the immune system has become an important reason for using dietary supplements, and many consumers are purchasing products through online platforms. <h3>Objectives</h3> To examine whether select dietary supplement products advertised as supporting or boosting the immune system are accurately labeled according to the Supplement Facts label of listed ingredients and to qualitatively describe the product labels’ characteristics in terms of claims made. <h3>Design, Setting, and Participants</h3> In this case series, 30 featured immune health dietary supplements were selected and purchased from Amazon.com in May 2021. Product analysis was performed using liquid chromatography–mass spectrometry. The list of ingredients detected through analysis for each product was compared with the ingredients on the product’s Supplement Facts label to determine whether the product’s label was accurate. Claims made on product labels were also evaluated by using the Operation Supplement Safety Scorecard’s set of questions to describe the labels’ characteristics. <h3>Results</h3> A total of 30 select dietary supplement products were evaluated. Thirteen of the 30 products had accurate labels based on the product analysis. Of the 17 products with inaccurate labels, 13 had ingredients listed on the labels that were not detected through analysis, such that their labels were misbranded. Nine products had substances detected that were not claimed on the product labels, some of which may be considered adulterated. Five were misbranded and contained additional components not claimed on the label. No product had third-party certification seals present on the packaging. Ten of the 13 products with accurate labels received a score of 4 or more when applying the Operation Supplement Safety Scorecard, meaning the product was “likely okay/less risky.” <h3>Conclusions and Relevance</h3> In this case series study, most of the products tested had inaccurate labels and claims that were inconsistent with requirements the US Food and Drug Administration has put forward for dietary supplements. Quality control measures seem to be insufficient for most of these select products, and claims made on labels may be misleading consumers who purchase products." @default.
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• W4293496876 date "2022-08-10" @default.
• W4293496876 modified "2023-09-26" @default.
• W4293496876 title "Analysis of Select Dietary Supplement Products Marketed to Support or Boost the Immune System" @default.
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• W4293496876 doi "https://doi.org/10.1001/jamanetworkopen.2022.26040" @default.
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