Matches in SemOpenAlex for { <https://semopenalex.org/work/W4293537701> ?p ?o ?g. }
- W4293537701 abstract "ABSTRACT Alternative splicing is an important source of heterogeneity in gene expression between individual cells but remains an understudied area due to the paucity of computational tools to analyze splicing dynamics at single-cell resolution. Here, we present MARVEL, a comprehensive R package for single-cell splicing analysis applicable to RNA sequencing generated from the plate- and droplet-based methods. We performed extensive benchmarking of MARVEL against available tools and demonstrated its utility by analyzing iPSC differentiation into endoderm cells and cardiomyocytes. MARVEL enables systematic and integrated splicing and gene expression analysis of single cells to characterize the splicing landscape and reveal biological insights." @default.
- W4293537701 created "2022-08-30" @default.
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- W4293537701 date "2022-08-26" @default.
- W4293537701 modified "2023-10-02" @default.
- W4293537701 title "MARVEL: An integrated alternative splicing analysis platform for single-cell RNA sequencing data" @default.
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- W4293537701 doi "https://doi.org/10.1101/2022.08.25.505258" @default.
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