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- W4293572247 abstract "Abstract Chirality is an intrinsic feature of nature and plays a crucial role in molecular translocation. However, how chirality affects or even more strongly affects DNA translocation remains largely unknown. Here, a facile and feasible strategy was contributed for the construction of chiral pillar[5]arene‐modified nanochannels (D/L‐Phe‐P5 nanochannels) that can enhance recognition and accelerate DNA translocation. The results showed the L‐Phe‐P5 nanochannel elevated the DNA translocation efficiency by about 6.59‐fold compared to the Mono‐L‐Phe‐P5 channel. Furthermore, the translocation efficiency of the L‐Phe‐P5 nanochannel with multi‐chiral centers was 3.06‐fold higher than that of the D‐Phe‐P5 nanochannel, and this value was 2.25‐fold higher than the ratio of the translocation efficiency between the Mono‐L‐Phe‐P5 channel and Mono‐D‐Phe‐P5 channel. Finally, the theoretical simulation and analysis of the translocation mechanism were performed by COMSOL Multiphysics software. This research not only enriches the basic theory research related to the influence of chirality on DNA translocation, but also has great reference value for the further development of DNA application. More importantly, the chiral amplification strategy could also extend to the selectivity of other chiral biomolecules, which may have potentially far‐reaching implications." @default.
- W4293572247 created "2022-08-30" @default.
- W4293572247 creator A5053447705 @default.
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- W4293572247 creator A5074354102 @default.
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- W4293572247 creator A5085131227 @default.
- W4293572247 date "2022-09-15" @default.
- W4293572247 modified "2023-10-15" @default.
- W4293572247 title "Construction of Pillar[5]arene‐based Nanochannels with Chiral‐enhanced DNA Translocation Ability" @default.
- W4293572247 cites W1560940442 @default.
- W4293572247 cites W1587969070 @default.
- W4293572247 cites W1804590457 @default.
- W4293572247 cites W1893543960 @default.
- W4293572247 cites W1977732116 @default.
- W4293572247 cites W1986199891 @default.
- W4293572247 cites W1988286342 @default.
- W4293572247 cites W1989474885 @default.
- W4293572247 cites W1991640081 @default.
- W4293572247 cites W1997010525 @default.
- W4293572247 cites W1999865751 @default.
- W4293572247 cites W2006588853 @default.
- W4293572247 cites W2016014994 @default.
- W4293572247 cites W2023353304 @default.
- W4293572247 cites W2028939683 @default.
- W4293572247 cites W2042086259 @default.
- W4293572247 cites W2045295398 @default.
- W4293572247 cites W2049721533 @default.
- W4293572247 cites W2051374206 @default.
- W4293572247 cites W2054471595 @default.
- W4293572247 cites W2058713133 @default.
- W4293572247 cites W2061668767 @default.
- W4293572247 cites W2062539580 @default.
- W4293572247 cites W2064500797 @default.
- W4293572247 cites W2065951872 @default.
- W4293572247 cites W2067799429 @default.
- W4293572247 cites W2069838866 @default.
- W4293572247 cites W2070256366 @default.
- W4293572247 cites W2070419242 @default.
- W4293572247 cites W2077398573 @default.
- W4293572247 cites W2079694107 @default.
- W4293572247 cites W2082178832 @default.
- W4293572247 cites W2082339363 @default.
- W4293572247 cites W2083872370 @default.
- W4293572247 cites W2084774024 @default.
- W4293572247 cites W2085183831 @default.
- W4293572247 cites W2086098872 @default.
- W4293572247 cites W2087013038 @default.
- W4293572247 cites W2092583600 @default.
- W4293572247 cites W2103646358 @default.
- W4293572247 cites W2103874054 @default.
- W4293572247 cites W2122503439 @default.
- W4293572247 cites W2134718143 @default.
- W4293572247 cites W2139446350 @default.
- W4293572247 cites W2144236452 @default.
- W4293572247 cites W2144400286 @default.
- W4293572247 cites W2168655386 @default.
- W4293572247 cites W2171712336 @default.
- W4293572247 cites W2231373328 @default.
- W4293572247 cites W2309781408 @default.
- W4293572247 cites W2315816115 @default.
- W4293572247 cites W2320665797 @default.
- W4293572247 cites W2404593662 @default.
- W4293572247 cites W2404939090 @default.
- W4293572247 cites W2477509602 @default.
- W4293572247 cites W2491990351 @default.
- W4293572247 cites W2496132953 @default.
- W4293572247 cites W2511725062 @default.
- W4293572247 cites W2547689139 @default.
- W4293572247 cites W2550427659 @default.
- W4293572247 cites W2564574018 @default.
- W4293572247 cites W2612476367 @default.
- W4293572247 cites W2763443067 @default.
- W4293572247 cites W2793585092 @default.
- W4293572247 cites W2896741233 @default.
- W4293572247 cites W2898898754 @default.
- W4293572247 cites W2915739865 @default.
- W4293572247 cites W2916361025 @default.
- W4293572247 cites W2943505030 @default.
- W4293572247 cites W2975580126 @default.
- W4293572247 cites W2999083891 @default.
- W4293572247 cites W3014593332 @default.
- W4293572247 cites W3018231014 @default.
- W4293572247 cites W3022310118 @default.
- W4293572247 cites W3084085446 @default.
- W4293572247 cites W3146731142 @default.
- W4293572247 cites W3174806465 @default.
- W4293572247 cites W3200810845 @default.
- W4293572247 cites W4224937282 @default.
- W4293572247 cites W4242745642 @default.
- W4293572247 cites W4251583264 @default.
- W4293572247 cites W4281253620 @default.
- W4293572247 cites W4292078711 @default.
- W4293572247 doi "https://doi.org/10.1002/cnma.202200342" @default.
- W4293572247 hasPublicationYear "2022" @default.
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