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• W4293579042 abstract "Background and Aims : Obesity is a risk factor for chronic kidney disease (CKD). The aim of this study was to investigate quality of life and psychological status in older patients with СKD and obesity.Methods: 472 older patients with stable cardiovascular diseases (231 males, mean age 69,6±7,3years) were studied. CKD was diagnosed and classified according to the KDIGO guidelines (2012). Nutritional status (presence and type of obesity, body composition) was assessed. Quality of life, psychological status and defense mechanisms were studied.Results: CKD with GFR less than 60 ml/min/1.73 m2 was diagnosed in 277 (58.7%) patients. Overweight was observed in 111 (40.1%) patients, obesity - in 118 (42.6%) patients with CKD. More than half had grade 1 obesity (70; 59.3%), every fourth (30; 25.4) - grade 2, 18 (15.3%) - grade 3 among obese patients with CKD. All older patients with CKD had an increase in adipose tissue. Obesity in patients with CKD was associated with immature psychological defense mechanisms denial (36 (18; 55) and 27 (9; 45)% scores, resp., p = 0.005) and substitution (10 (0; 20) and 0 (0; 10)% scores, resp., p = 0.01) compared with patients without obesity. Patients with obesity were characterized by passive aggressiveness, difficulties of social adaptation. Older patients with CKD and obesity had lower indicators on the social functioning scale (quality of life questionnaire SF-36) (37.5 (37.5; 50) and 50 (37, 5; 62.5) points, resp., p = 0.03) compared with patients without obesity.Conclusions: Older patients with CKD are characterized by sarcopenic obesity, which leads to impaired social functioning. Background and Aims : Obesity is a risk factor for chronic kidney disease (CKD). The aim of this study was to investigate quality of life and psychological status in older patients with СKD and obesity. Methods: 472 older patients with stable cardiovascular diseases (231 males, mean age 69,6±7,3years) were studied. CKD was diagnosed and classified according to the KDIGO guidelines (2012). Nutritional status (presence and type of obesity, body composition) was assessed. Quality of life, psychological status and defense mechanisms were studied. Results: CKD with GFR less than 60 ml/min/1.73 m2 was diagnosed in 277 (58.7%) patients. Overweight was observed in 111 (40.1%) patients, obesity - in 118 (42.6%) patients with CKD. More than half had grade 1 obesity (70; 59.3%), every fourth (30; 25.4) - grade 2, 18 (15.3%) - grade 3 among obese patients with CKD. All older patients with CKD had an increase in adipose tissue. Obesity in patients with CKD was associated with immature psychological defense mechanisms denial (36 (18; 55) and 27 (9; 45)% scores, resp., p = 0.005) and substitution (10 (0; 20) and 0 (0; 10)% scores, resp., p = 0.01) compared with patients without obesity. Patients with obesity were characterized by passive aggressiveness, difficulties of social adaptation. Older patients with CKD and obesity had lower indicators on the social functioning scale (quality of life questionnaire SF-36) (37.5 (37.5; 50) and 50 (37, 5; 62.5) points, resp., p = 0.03) compared with patients without obesity. Conclusions: Older patients with CKD are characterized by sarcopenic obesity, which leads to impaired social functioning." @default.
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• W4293579042 date "2022-08-01" @default.
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• W4293579042 title "Quality of life in older patients with obesity and chronic kidney disease" @default.
• W4293579042 doi "https://doi.org/10.1016/j.atherosclerosis.2022.06.804" @default.
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