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- W4293581590 abstract "Gum Ghatti(GG) on topical application accelerates wound healing,similarl ypectin is widely used in wound dressing materials. However development of composite hydrogel using synergistic interaction of both gum ghatti and pectin and research characterizing their properties is scare. Synergistic advantages of both natural polymers were utilized in designing new antibiotic eluting biodegradable hydrogel film without using synthetic polymer for slow release of ciprofloxacin hydrochloride and the engineering aspects of the film were emphasized. Initially gum ghatti (GG) was modified to sodium carboxymethyl gum ghatti (NaCMGG) and then NaCMGG-pectin film were prepared by solvent casting method followed by crosslinking in AlCl 3 solution (18% to 22% w/v) for 2 to 20mins. Swelling indices of low crosslinked film (LCL) and high crosslinked film (HCL) were 67% and 53% respectively that prevent accumulation of exudates in wound . The water vapour transmission rate of HCL and LCL were 511.36 gm/m2/day and 568.18 gm/m2/day respectively,maintaining moist environment over the wound. Molecular evidence of probable healing mechanism could be found in in-vivo model." @default.
- W4293581590 created "2022-08-30" @default.
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- W4293581590 date "2022-10-01" @default.
- W4293581590 modified "2023-10-16" @default.
- W4293581590 title "Tuned Gum ghatti and pectin for green synthesis of novel wound dressing material: Engineering aspects and in vivo study" @default.
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- W4293581590 doi "https://doi.org/10.1016/j.jddst.2022.103730" @default.
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