FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4293704844> ?p ?o ?g. }

• W4293704844 abstract "Rapid antigen tests (RAgTs) for SARS-CoV-2 are considered adequate for diagnosis at the point of care. Our objective was to establish the agreement between reverse transcription-quantitative polymerase chain reaction (RT-qPCR) and RAgTs in the pediatric population.All patients aged 1 month to 17 years and 11 months seen at the Emergency Fever Unit of a children's hospital between 6-11-2021 and 10-3-2021 were recruited. The Panbio COVID-19 Ag® test (Abbott Diagnostic) was compared to the reference method RT-qPCR (as per the protocol suggested by the United States Centers for Disease Control and Prevention).A total of 6491 patients were included. The prevalence of COVID-19 was 2.8%. Symptoms were observed in 92.1%. Sensitivity, specificity, and the kappa index of agreement for the RAgT were 71.0%, 99.9%, and 0.813, respectively. The kappa index and the RAgT sensitivity were significantly higher in the group aged 13-17 years (0.89 and 82.4%, respectively) compared to the groups aged 0-5 and 6-12 years. This may be due to the lower viral load observed in patients younger than 12 years.Although RAgTs shorten the time to result and improve the isolation strategy for COVID-19 patients, their sensitivity in children younger than 12 years or asymptomatic children is not within the recommended ranges, especially during periods of low disease prevalence.Introducción. Los inmunoensayos de detección rápida de antígenos (TRA) del SARS-CoV-2, son considerados adecuados para el diagnóstico en el punto de atención. El objetivo fue conocer la concordancia entre la reacción en cadena de la polimerasa en tiempo real con transcriptasa inversa (RT-qPCR, por su sigla en inglés) y los TRA en población pediátrica. Población y métodos. Se reclutaron todos los pacientes entre 1 mes y 17 años 11 meses de edad atendidos en la Unidad Febril de Urgencia de un hospital pediátrico entre el 11 de junio y el 3 de octubre de 2021. Se utilizó el TRA Panbio COVID-19 Ag® (Abbott Diagnostic) y, como método de referencia, la RT-qPCR (según el protocolo de los Centros para el Control y la Prevención de Enfermedades). Resultados. Se incluyeron 6491 pacientes. La prevalencia de COVID-19 fue del 2,8 %. El 92,1 % de los sujetos presentaron síntomas. La sensibilidad, la especificidad y el índice kappa de concordancia para el TRA fueron del 71,0 %, 99,9 % y 0,813, respectivamente. El índice kappa y la sensibilidad del TRA fueron significativamente mayores en el grupo de 13 a 17 años (0,89 y 82,4 %, respectivamente) cuando se los comparó con los grupos de 0 a 5 y de 6 a 12 años. Esto podría deberse a la menor carga viral observada en los pacientes menores de 12 años. Conclusión. Si bien los TRA permiten acortar el tiempo de obtención de los resultados y mejorar la estrategia de aislamiento de pacientes con COVID-19, la sensibilidad en niños menores de 12 años o asintomáticos no se encontraría dentro de los rangos recomendados, sobre todo en períodos de baja prevalencia de la enfermedad." @default.
• W4293704844 created "2022-08-31" @default.
• W4293704844 creator A5021041723 @default.
• W4293704844 creator A5027975112 @default.
• W4293704844 creator A5039666618 @default.
• W4293704844 creator A5044155792 @default.
• W4293704844 creator A5044362274 @default.
• W4293704844 creator A5056271587 @default.
• W4293704844 creator A5061751737 @default.
• W4293704844 creator A5078053755 @default.
• W4293704844 creator A5080872627 @default.
• W4293704844 creator A5089938868 @default.
• W4293704844 date "2022-10-01" @default.
• W4293704844 modified "2023-10-01" @default.
• W4293704844 title "Agreement between diagnostic methods for SARS-CoV-2 infection in children seen at the Emergency Department of a children’s hospital" @default.
• W4293704844 doi "https://doi.org/10.5546/aap.2022.eng.325" @default.
• W4293704844 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36190216" @default.
• W4293704844 hasPublicationYear "2022" @default.
• W4293704844 type Work @default.
• W4293704844 citedByCount "0" @default.
• W4293704844 crossrefType "journal-article" @default.
• W4293704844 hasAuthorship W4293704844A5021041723 @default.
• W4293704844 hasAuthorship W4293704844A5027975112 @default.
• W4293704844 hasAuthorship W4293704844A5039666618 @default.
• W4293704844 hasAuthorship W4293704844A5044155792 @default.
• W4293704844 hasAuthorship W4293704844A5044362274 @default.
• W4293704844 hasAuthorship W4293704844A5056271587 @default.
• W4293704844 hasAuthorship W4293704844A5061751737 @default.
• W4293704844 hasAuthorship W4293704844A5078053755 @default.
• W4293704844 hasAuthorship W4293704844A5080872627 @default.
• W4293704844 hasAuthorship W4293704844A5089938868 @default.
• W4293704844 hasBestOaLocation W42937048441 @default.
• W4293704844 hasConcept C118552586 @default.
• W4293704844 hasConcept C119857082 @default.
• W4293704844 hasConcept C126322002 @default.
• W4293704844 hasConcept C138885662 @default.
• W4293704844 hasConcept C163864269 @default.
• W4293704844 hasConcept C187212893 @default.
• W4293704844 hasConcept C2777910003 @default.
• W4293704844 hasConcept C2778724333 @default.
• W4293704844 hasConcept C2779134260 @default.
• W4293704844 hasConcept C2780724011 @default.
• W4293704844 hasConcept C2908647359 @default.
• W4293704844 hasConcept C3007834351 @default.
• W4293704844 hasConcept C3008058167 @default.
• W4293704844 hasConcept C41008148 @default.
• W4293704844 hasConcept C41895202 @default.
• W4293704844 hasConcept C524204448 @default.
• W4293704844 hasConcept C71924100 @default.
• W4293704844 hasConcept C99454951 @default.
• W4293704844 hasConceptScore W4293704844C118552586 @default.
• W4293704844 hasConceptScore W4293704844C119857082 @default.
• W4293704844 hasConceptScore W4293704844C126322002 @default.
• W4293704844 hasConceptScore W4293704844C138885662 @default.
• W4293704844 hasConceptScore W4293704844C163864269 @default.
• W4293704844 hasConceptScore W4293704844C187212893 @default.
• W4293704844 hasConceptScore W4293704844C2777910003 @default.
• W4293704844 hasConceptScore W4293704844C2778724333 @default.
• W4293704844 hasConceptScore W4293704844C2779134260 @default.
• W4293704844 hasConceptScore W4293704844C2780724011 @default.
• W4293704844 hasConceptScore W4293704844C2908647359 @default.
• W4293704844 hasConceptScore W4293704844C3007834351 @default.
• W4293704844 hasConceptScore W4293704844C3008058167 @default.
• W4293704844 hasConceptScore W4293704844C41008148 @default.
• W4293704844 hasConceptScore W4293704844C41895202 @default.
• W4293704844 hasConceptScore W4293704844C524204448 @default.
• W4293704844 hasConceptScore W4293704844C71924100 @default.
• W4293704844 hasConceptScore W4293704844C99454951 @default.
• W4293704844 hasIssue "5" @default.
• W4293704844 hasLocation W42937048441 @default.
• W4293704844 hasLocation W42937048442 @default.
• W4293704844 hasOpenAccess W4293704844 @default.
• W4293704844 hasPrimaryLocation W42937048441 @default.
• W4293704844 hasRelatedWork W1983972451 @default.
• W4293704844 hasRelatedWork W1995188757 @default.
• W4293704844 hasRelatedWork W2016679923 @default.
• W4293704844 hasRelatedWork W2108408227 @default.
• W4293704844 hasRelatedWork W2116001782 @default.
• W4293704844 hasRelatedWork W4229900919 @default.
• W4293704844 hasRelatedWork W4281684902 @default.
• W4293704844 hasRelatedWork W4309639323 @default.
• W4293704844 hasRelatedWork W4311787753 @default.
• W4293704844 hasRelatedWork W4319752858 @default.
• W4293704844 hasVolume "120" @default.
• W4293704844 isParatext "false" @default.
• W4293704844 isRetracted "false" @default.
• W4293704844 workType "article" @default.