FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4293722099> ?p ?o ?g. }

• W4293722099 endingPage "52" @default.
• W4293722099 startingPage "46" @default.
• W4293722099 abstract "Exposure to endocrine-disrupting chemicals (EDCs), such as arsenic, leads to severe health problems and surreptitiously accentuates stressful conditions in humans. Additionally, arsenic-induced endocrine stress leads to severe disturbances in glucose metabolism, mostly by disrupting the structure-function adroitness of the adrenal, thyroid and pancreas. Mechanistically, elevated levels of reactive oxygen species (ROS) generated by arsenic accentuate perturbation of cellular redox balance and eventually cell death. All-trans retinoic acid (ATRA), an active metabolite of vitamin A, is known for its anti-oxidant properties. Therefore, ATRA was used as a protection against arsenic-induced deteriorations of physiological conditions in mice. The present study reveals arsenic induced ROS generation in the adrenal and thyroid glands, accompanied by a decline in the activities of ROS scavenging enzymes, leading to disruption of the architecture of the tissues and induction of apoptosis therein, culminating in an imbalance in the hormonal secretions from the respective tissues. Structural damage to the pancreas accompanied with severe imbalances in glucose metabolism and associated biochemical parameters like glucose, pancreatic amylase and liver glycogen were also noted. Treatment with ATRA could efciently reverse the deleterious effects induced by arsenic. Hence, ATRA can be used as an efcient nutraceutical which can lead to attenuation of endocrine stress induced by arsenic." @default.
• W4293722099 created "2022-08-31" @default.
• W4293722099 creator A5033373800 @default.
• W4293722099 creator A5034487572 @default.
• W4293722099 creator A5056391953 @default.
• W4293722099 date "2022-08-01" @default.
• W4293722099 modified "2023-09-28" @default.
• W4293722099 title "ALL-TRANS RETINOIC ACID ALLEVIATES ARSENIC-INDUCED ENDOCRINE DISRUPTION IN SWISS ALBINO MICE" @default.
• W4293722099 cites W1031730619 @default.
• W4293722099 cites W1909761103 @default.
• W4293722099 cites W1961988715 @default.
• W4293722099 cites W1967344339 @default.
• W4293722099 cites W1970532350 @default.
• W4293722099 cites W1971639265 @default.
• W4293722099 cites W1972019547 @default.
• W4293722099 cites W1976294087 @default.
• W4293722099 cites W1989398852 @default.
• W4293722099 cites W2011801069 @default.
• W4293722099 cites W2012634735 @default.
• W4293722099 cites W2020089167 @default.
• W4293722099 cites W2023648659 @default.
• W4293722099 cites W2027438949 @default.
• W4293722099 cites W2037082754 @default.
• W4293722099 cites W2056583482 @default.
• W4293722099 cites W2068120083 @default.
• W4293722099 cites W2073092594 @default.
• W4293722099 cites W2084235593 @default.
• W4293722099 cites W2088866343 @default.
• W4293722099 cites W2092983079 @default.
• W4293722099 cites W2107156968 @default.
• W4293722099 cites W2114525006 @default.
• W4293722099 cites W2132958974 @default.
• W4293722099 cites W2140285300 @default.
• W4293722099 cites W2148649159 @default.
• W4293722099 cites W2162991306 @default.
• W4293722099 cites W2322752311 @default.
• W4293722099 cites W2418010073 @default.
• W4293722099 cites W2503130819 @default.
• W4293722099 cites W2616791270 @default.
• W4293722099 cites W2621201948 @default.
• W4293722099 cites W2626441385 @default.
• W4293722099 cites W2742840075 @default.
• W4293722099 cites W2765429845 @default.
• W4293722099 cites W2766732549 @default.
• W4293722099 cites W2792140277 @default.
• W4293722099 cites W2804676384 @default.
• W4293722099 cites W2890131737 @default.
• W4293722099 cites W2899755734 @default.
• W4293722099 cites W2915668822 @default.
• W4293722099 cites W2922056270 @default.
• W4293722099 cites W2922546557 @default.
• W4293722099 cites W2953781976 @default.
• W4293722099 cites W2969579339 @default.
• W4293722099 cites W3085746594 @default.
• W4293722099 doi "https://doi.org/10.36106/ijsr/1721880" @default.
• W4293722099 hasPublicationYear "2022" @default.
• W4293722099 type Work @default.
• W4293722099 citedByCount "0" @default.
• W4293722099 crossrefType "journal-article" @default.
• W4293722099 hasAuthorship W4293722099A5033373800 @default.
• W4293722099 hasAuthorship W4293722099A5034487572 @default.
• W4293722099 hasAuthorship W4293722099A5056391953 @default.
• W4293722099 hasConcept C104317684 @default.
• W4293722099 hasConcept C126322002 @default.
• W4293722099 hasConcept C134018914 @default.
• W4293722099 hasConcept C172507514 @default.
• W4293722099 hasConcept C178790620 @default.
• W4293722099 hasConcept C185592680 @default.
• W4293722099 hasConcept C2776151105 @default.
• W4293722099 hasConcept C2778764654 @default.
• W4293722099 hasConcept C2781121885 @default.
• W4293722099 hasConcept C46699223 @default.
• W4293722099 hasConcept C48349386 @default.
• W4293722099 hasConcept C502230775 @default.
• W4293722099 hasConcept C526584372 @default.
• W4293722099 hasConcept C55493867 @default.
• W4293722099 hasConcept C71315377 @default.
• W4293722099 hasConcept C71924100 @default.
• W4293722099 hasConcept C86803240 @default.
• W4293722099 hasConceptScore W4293722099C104317684 @default.
• W4293722099 hasConceptScore W4293722099C126322002 @default.
• W4293722099 hasConceptScore W4293722099C134018914 @default.
• W4293722099 hasConceptScore W4293722099C172507514 @default.
• W4293722099 hasConceptScore W4293722099C178790620 @default.
• W4293722099 hasConceptScore W4293722099C185592680 @default.
• W4293722099 hasConceptScore W4293722099C2776151105 @default.
• W4293722099 hasConceptScore W4293722099C2778764654 @default.
• W4293722099 hasConceptScore W4293722099C2781121885 @default.
• W4293722099 hasConceptScore W4293722099C46699223 @default.
• W4293722099 hasConceptScore W4293722099C48349386 @default.
• W4293722099 hasConceptScore W4293722099C502230775 @default.
• W4293722099 hasConceptScore W4293722099C526584372 @default.
• W4293722099 hasConceptScore W4293722099C55493867 @default.
• W4293722099 hasConceptScore W4293722099C71315377 @default.
• W4293722099 hasConceptScore W4293722099C71924100 @default.
• W4293722099 hasConceptScore W4293722099C86803240 @default.
• W4293722099 hasLocation W42937220991 @default.
• W4293722099 hasOpenAccess W4293722099 @default.

• next