Matches in SemOpenAlex for { <https://semopenalex.org/work/W4293764382> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W4293764382 endingPage "13" @default.
- W4293764382 startingPage "4" @default.
- W4293764382 abstract "Abortion is common worldwide and increasingly abortions are performed at less than 14 weeks' gestation using medical methods, specifically using a combination of mifepristone and misoprostol. Medical abortion is known to be a painful process, but the optimal method of pain management is unclear. We sought to identify and compare pain management regimens for medical abortion before 14 weeks' gestation.We conducted our search in August 2019 and included randomized controlled trials (RCT) and observational studies of any pain relief intervention (pharmacological and non-pharmacological) for mifepristone-misoprostol combination medical abortion of pregnancies less than 14 weeks' gestation.We included four RCTs and one observational study. Due to the heterogeneity of study designs, interventions and outcome reporting, meta-analysis was not possible. Only one study found evidence of an effect between interventions on pain score: a prophylactic dose of ibuprofen 1600mg likely reduces the pain score when compared to a dose of paracetamol 2000mg (MD 2.26/10 [CI 3-1.52 lower]). For other interventions (pregabalin 300mg vs placebo; ibuprofen 800mg vs placebo; therapeutic vs prophylactic administration of ibuprofen 800mg; ambulation vs non-ambulation during treatment) there appeared to be little to no difference with comparator.The findings of this review provide some support for the use of ibuprofen as a single dose given with misoprostol prophylactically, or in response to pain as needed. The optimal dosing of ibuprofen is unclear, but a single dose of ibuprofen 1600mg was shown to be effective and it was less certain whether 800mg was effective." @default.
- W4293764382 created "2022-08-31" @default.
- W4293764382 creator A5013522880 @default.
- W4293764382 creator A5042849457 @default.
- W4293764382 creator A5073955441 @default.
- W4293764382 creator A5091154429 @default.
- W4293764382 date "2022-12-01" @default.
- W4293764382 modified "2023-10-18" @default.
- W4293764382 title "Pain management for medical abortion before 14 weeks’ gestation: A systematic review" @default.
- W4293764382 cites W1964032731 @default.
- W4293764382 cites W1997971322 @default.
- W4293764382 cites W2010933622 @default.
- W4293764382 cites W2053173231 @default.
- W4293764382 cites W2112561589 @default.
- W4293764382 cites W2120504453 @default.
- W4293764382 cites W2156098321 @default.
- W4293764382 cites W2165010366 @default.
- W4293764382 cites W2531269403 @default.
- W4293764382 cites W2756784389 @default.
- W4293764382 cites W2885320216 @default.
- W4293764382 cites W2970684805 @default.
- W4293764382 cites W2991792334 @default.
- W4293764382 doi "https://doi.org/10.1016/j.contraception.2022.08.005" @default.
- W4293764382 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36055363" @default.
- W4293764382 hasPublicationYear "2022" @default.
- W4293764382 type Work @default.
- W4293764382 citedByCount "3" @default.
- W4293764382 countsByYear W42937643822023 @default.
- W4293764382 crossrefType "journal-article" @default.
- W4293764382 hasAuthorship W4293764382A5013522880 @default.
- W4293764382 hasAuthorship W4293764382A5042849457 @default.
- W4293764382 hasAuthorship W4293764382A5073955441 @default.
- W4293764382 hasAuthorship W4293764382A5091154429 @default.
- W4293764382 hasBestOaLocation W42937643821 @default.
- W4293764382 hasConcept C126322002 @default.
- W4293764382 hasConcept C131872663 @default.
- W4293764382 hasConcept C142724271 @default.
- W4293764382 hasConcept C168563851 @default.
- W4293764382 hasConcept C204787440 @default.
- W4293764382 hasConcept C23131810 @default.
- W4293764382 hasConcept C27081682 @default.
- W4293764382 hasConcept C2777288759 @default.
- W4293764382 hasConcept C2778642596 @default.
- W4293764382 hasConcept C2778826759 @default.
- W4293764382 hasConcept C2779199973 @default.
- W4293764382 hasConcept C2779234561 @default.
- W4293764382 hasConcept C2779560327 @default.
- W4293764382 hasConcept C2779944601 @default.
- W4293764382 hasConcept C42219234 @default.
- W4293764382 hasConcept C46973012 @default.
- W4293764382 hasConcept C54355233 @default.
- W4293764382 hasConcept C71924100 @default.
- W4293764382 hasConcept C86803240 @default.
- W4293764382 hasConcept C98274493 @default.
- W4293764382 hasConceptScore W4293764382C126322002 @default.
- W4293764382 hasConceptScore W4293764382C131872663 @default.
- W4293764382 hasConceptScore W4293764382C142724271 @default.
- W4293764382 hasConceptScore W4293764382C168563851 @default.
- W4293764382 hasConceptScore W4293764382C204787440 @default.
- W4293764382 hasConceptScore W4293764382C23131810 @default.
- W4293764382 hasConceptScore W4293764382C27081682 @default.
- W4293764382 hasConceptScore W4293764382C2777288759 @default.
- W4293764382 hasConceptScore W4293764382C2778642596 @default.
- W4293764382 hasConceptScore W4293764382C2778826759 @default.
- W4293764382 hasConceptScore W4293764382C2779199973 @default.
- W4293764382 hasConceptScore W4293764382C2779234561 @default.
- W4293764382 hasConceptScore W4293764382C2779560327 @default.
- W4293764382 hasConceptScore W4293764382C2779944601 @default.
- W4293764382 hasConceptScore W4293764382C42219234 @default.
- W4293764382 hasConceptScore W4293764382C46973012 @default.
- W4293764382 hasConceptScore W4293764382C54355233 @default.
- W4293764382 hasConceptScore W4293764382C71924100 @default.
- W4293764382 hasConceptScore W4293764382C86803240 @default.
- W4293764382 hasConceptScore W4293764382C98274493 @default.
- W4293764382 hasFunder F4320334626 @default.
- W4293764382 hasLocation W42937643821 @default.
- W4293764382 hasLocation W42937643822 @default.
- W4293764382 hasLocation W42937643823 @default.
- W4293764382 hasOpenAccess W4293764382 @default.
- W4293764382 hasPrimaryLocation W42937643821 @default.
- W4293764382 hasRelatedWork W1602576566 @default.
- W4293764382 hasRelatedWork W2004394272 @default.
- W4293764382 hasRelatedWork W2016603468 @default.
- W4293764382 hasRelatedWork W2029521764 @default.
- W4293764382 hasRelatedWork W2362889847 @default.
- W4293764382 hasRelatedWork W2382213285 @default.
- W4293764382 hasRelatedWork W2563196148 @default.
- W4293764382 hasRelatedWork W2911223620 @default.
- W4293764382 hasRelatedWork W3013810766 @default.
- W4293764382 hasRelatedWork W4245803215 @default.
- W4293764382 hasVolume "116" @default.
- W4293764382 isParatext "false" @default.
- W4293764382 isRetracted "false" @default.
- W4293764382 workType "article" @default.