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- W4293770732 endingPage "588" @default.
- W4293770732 startingPage "588" @default.
- W4293770732 abstract "The genus Pyrenophora includes two important cereal crop foliar pathogens and a large number of less well-known species, many of which are also grass pathogens. Only a few of these have been examined in terms of secondary metabolite production, yet even these few species have yielded a remarkable array of bioactive metabolites that include compounds produced through each of the major biosynthetic pathways. There is little overlap among species in the compounds identified. Pyrenophora tritici-repentis produces protein toxin effectors that mediate host-specific responses as well as spirocyclic lactams and at least one anthraquinone. Pyrenophora teres produces marasmine amino acid and isoquinoline derivatives involved in pathogenesis on barley as well as nonenolides with antifungal activity, while P. semeniperda produces cytochalasans and sesquiterpenoids implicated in pathogenesis on seeds as well as spirocyclic lactams with phytotoxic and antibacterial activity. Less well-known species have produced some unusual macrocyclic compounds in addition to a diverse array of anthraquinones. For the three best-studied species, in silico genome mining has predicted the existence of biosynthetic pathways for a much larger array of potentially toxic secondary metabolites than has yet been produced in culture. Most compounds identified to date have potentially useful biological activity." @default.
- W4293770732 created "2022-08-31" @default.
- W4293770732 creator A5041233168 @default.
- W4293770732 creator A5063443142 @default.
- W4293770732 creator A5070414038 @default.
- W4293770732 date "2022-08-27" @default.
- W4293770732 modified "2023-10-14" @default.
- W4293770732 title "Bioactive Metabolite Production in the Genus Pyrenophora (Pleosporaceae, Pleosporales)" @default.
- W4293770732 cites W1524578392 @default.
- W4293770732 cites W1528234579 @default.
- W4293770732 cites W1549570039 @default.
- W4293770732 cites W1566548687 @default.
- W4293770732 cites W1587447716 @default.
- W4293770732 cites W1760403621 @default.
- W4293770732 cites W195977463 @default.
- W4293770732 cites W1965711491 @default.
- W4293770732 cites W1966890833 @default.
- W4293770732 cites W1968568970 @default.
- W4293770732 cites W1970313346 @default.
- W4293770732 cites W1970592860 @default.
- W4293770732 cites W1972574477 @default.
- W4293770732 cites W1974546765 @default.
- W4293770732 cites W1974701793 @default.
- W4293770732 cites W1976732426 @default.
- W4293770732 cites W1977842608 @default.
- W4293770732 cites W1977902174 @default.
- W4293770732 cites W1978466236 @default.
- W4293770732 cites W1979535667 @default.
- W4293770732 cites W1983924153 @default.
- W4293770732 cites W1992688335 @default.
- W4293770732 cites W1994082338 @default.
- W4293770732 cites W1995095970 @default.
- W4293770732 cites W1997281514 @default.
- W4293770732 cites W2001042979 @default.
- W4293770732 cites W2001554597 @default.
- W4293770732 cites W2002836667 @default.
- W4293770732 cites W2003482450 @default.
- W4293770732 cites W2004325025 @default.
- W4293770732 cites W2006187897 @default.
- W4293770732 cites W2010858670 @default.
- W4293770732 cites W2012173484 @default.
- W4293770732 cites W2015767486 @default.
- W4293770732 cites W2015784032 @default.
- W4293770732 cites W2018284126 @default.
- W4293770732 cites W2018920860 @default.
- W4293770732 cites W2020047834 @default.
- W4293770732 cites W2026015134 @default.
- W4293770732 cites W2028393407 @default.
- W4293770732 cites W2031450961 @default.
- W4293770732 cites W2036622942 @default.
- W4293770732 cites W2037207825 @default.
- W4293770732 cites W2038504372 @default.
- W4293770732 cites W2038775459 @default.
- W4293770732 cites W2040737298 @default.
- W4293770732 cites W2041323897 @default.
- W4293770732 cites W2041870733 @default.
- W4293770732 cites W2044915598 @default.
- W4293770732 cites W2044923377 @default.
- W4293770732 cites W2045402584 @default.
- W4293770732 cites W2046582874 @default.
- W4293770732 cites W2046688106 @default.
- W4293770732 cites W2049187992 @default.
- W4293770732 cites W2063673750 @default.
- W4293770732 cites W2064268502 @default.
- W4293770732 cites W2072648146 @default.
- W4293770732 cites W2073060607 @default.
- W4293770732 cites W2073430470 @default.
- W4293770732 cites W2077679187 @default.
- W4293770732 cites W2080931596 @default.
- W4293770732 cites W2085792626 @default.
- W4293770732 cites W2087722633 @default.
- W4293770732 cites W2093939951 @default.
- W4293770732 cites W2095476254 @default.
- W4293770732 cites W2103339654 @default.
- W4293770732 cites W2114492842 @default.
- W4293770732 cites W2118554142 @default.
- W4293770732 cites W2121427895 @default.
- W4293770732 cites W2122511603 @default.
- W4293770732 cites W2130772593 @default.
- W4293770732 cites W2131355475 @default.
- W4293770732 cites W2134185878 @default.
- W4293770732 cites W2134582896 @default.
- W4293770732 cites W2135256144 @default.
- W4293770732 cites W2137437022 @default.
- W4293770732 cites W2140868536 @default.
- W4293770732 cites W2143906556 @default.
- W4293770732 cites W2146057763 @default.
- W4293770732 cites W2149024951 @default.
- W4293770732 cites W2153802362 @default.
- W4293770732 cites W2169819624 @default.
- W4293770732 cites W2178472622 @default.
- W4293770732 cites W2198287101 @default.
- W4293770732 cites W2290121856 @default.
- W4293770732 cites W2295808952 @default.
- W4293770732 cites W2319030261 @default.
- W4293770732 cites W2319063465 @default.
- W4293770732 cites W2399741136 @default.
- W4293770732 cites W2399951068 @default.