FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4293771029> ?p ?o ?g. }

• W4293771029 endingPage "9189" @default.
• W4293771029 startingPage "9181" @default.
• W4293771029 abstract "Chemotherapy-induced febrile neutropenia (FN) is a life-threatening and chemotherapy dose-limiting adverse event. FN can be prevented with granulocyte-colony stimulating factors (G-CSFs). Guidelines recommend primary G-CSF use for patients receiving either high (> 20%) FN risk (HR) chemotherapy, or intermediate (10-20%) FN risk (IR) chemotherapy if the overall risk with additional patient-related risk factors exceeds 20%. In this study, we applied an EHR text-mining tool for real-world G-CSF treatment evaluation in breast cancer patients.Breast cancer patients receiving IR or HR chemotherapy treatments between January 2015 and February 2021 at LUMC, the Netherlands, were included. We retrospectively collected data from EHR with a text-mining tool and assessed G-CSF use, risk factors, and the FN and neutropenia (grades 3-4) and incidence.A total of 190 female patients were included, who received 77 HR and 113 IR treatments. In 88.3% of the HR regimens, G-CSF was administered; 7.3% of these patients developed FN vs. 33.3% without G-CSF. Although most IR regimen patients had ≥ 2 risk factors, only 4% received G-CSF, of which none developed neutropenia. However, without G-CSF, 11.9% developed FN and 31.2% severe neutropenia.Our text-mining study shows high G-CSF use among HR regimen patients, and low use among IR regimen patients, although most had ≥ 2 risk factors. Therefore, current practice is not completely in accordance with the guidelines. This shows the need for increased awareness and clarity regarding risk factors. Also, text-mining can effectively be implemented for the evaluation of patient care." @default.
• W4293771029 created "2022-08-31" @default.
• W4293771029 creator A5006908595 @default.
• W4293771029 creator A5010512189 @default.
• W4293771029 creator A5034722090 @default.
• W4293771029 creator A5050330413 @default.
• W4293771029 creator A5061463742 @default.
• W4293771029 creator A5076321542 @default.
• W4293771029 date "2022-08-31" @default.
• W4293771029 modified "2023-09-30" @default.
• W4293771029 title "Real-world evaluation of supportive care using an electronic health record text-mining tool: G-CSF use in breast cancer patients" @default.
• W4293771029 cites W1932756735 @default.
• W4293771029 cites W1982196884 @default.
• W4293771029 cites W2031497779 @default.
• W4293771029 cites W2084119896 @default.
• W4293771029 cites W2084474661 @default.
• W4293771029 cites W2087440397 @default.
• W4293771029 cites W2110645520 @default.
• W4293771029 cites W2131596319 @default.
• W4293771029 cites W2140302476 @default.
• W4293771029 cites W2169403306 @default.
• W4293771029 cites W2513382862 @default.
• W4293771029 cites W2517388783 @default.
• W4293771029 cites W2737000731 @default.
• W4293771029 cites W2745560856 @default.
• W4293771029 cites W2755733167 @default.
• W4293771029 cites W2801725918 @default.
• W4293771029 cites W2807063093 @default.
• W4293771029 cites W2894230777 @default.
• W4293771029 cites W2910326837 @default.
• W4293771029 cites W2917157846 @default.
• W4293771029 cites W2930139824 @default.
• W4293771029 cites W2939616315 @default.
• W4293771029 cites W2967056613 @default.
• W4293771029 cites W2996476125 @default.
• W4293771029 cites W2998842333 @default.
• W4293771029 cites W2999700331 @default.
• W4293771029 cites W3016716571 @default.
• W4293771029 cites W3020017041 @default.
• W4293771029 cites W3036449870 @default.
• W4293771029 cites W3036980661 @default.
• W4293771029 cites W3083763733 @default.
• W4293771029 cites W3112724540 @default.
• W4293771029 doi "https://doi.org/10.1007/s00520-022-07343-5" @default.
• W4293771029 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36044088" @default.
• W4293771029 hasPublicationYear "2022" @default.
• W4293771029 type Work @default.
• W4293771029 citedByCount "2" @default.
• W4293771029 countsByYear W42937710292022 @default.
• W4293771029 countsByYear W42937710292023 @default.
• W4293771029 crossrefType "journal-article" @default.
• W4293771029 hasAuthorship W4293771029A5006908595 @default.
• W4293771029 hasAuthorship W4293771029A5010512189 @default.
• W4293771029 hasAuthorship W4293771029A5034722090 @default.
• W4293771029 hasAuthorship W4293771029A5050330413 @default.
• W4293771029 hasAuthorship W4293771029A5061463742 @default.
• W4293771029 hasAuthorship W4293771029A5076321542 @default.
• W4293771029 hasBestOaLocation W42937710291 @default.
• W4293771029 hasConcept C121608353 @default.
• W4293771029 hasConcept C126322002 @default.
• W4293771029 hasConcept C143998085 @default.
• W4293771029 hasConcept C197934379 @default.
• W4293771029 hasConcept C2776694085 @default.
• W4293771029 hasConcept C2777063308 @default.
• W4293771029 hasConcept C2777767877 @default.
• W4293771029 hasConcept C2778336483 @default.
• W4293771029 hasConcept C2778850193 @default.
• W4293771029 hasConcept C2781413609 @default.
• W4293771029 hasConcept C530470458 @default.
• W4293771029 hasConcept C71924100 @default.
• W4293771029 hasConceptScore W4293771029C121608353 @default.
• W4293771029 hasConceptScore W4293771029C126322002 @default.
• W4293771029 hasConceptScore W4293771029C143998085 @default.
• W4293771029 hasConceptScore W4293771029C197934379 @default.
• W4293771029 hasConceptScore W4293771029C2776694085 @default.
• W4293771029 hasConceptScore W4293771029C2777063308 @default.
• W4293771029 hasConceptScore W4293771029C2777767877 @default.
• W4293771029 hasConceptScore W4293771029C2778336483 @default.
• W4293771029 hasConceptScore W4293771029C2778850193 @default.
• W4293771029 hasConceptScore W4293771029C2781413609 @default.
• W4293771029 hasConceptScore W4293771029C530470458 @default.
• W4293771029 hasConceptScore W4293771029C71924100 @default.
• W4293771029 hasIssue "11" @default.
• W4293771029 hasLocation W42937710291 @default.
• W4293771029 hasLocation W42937710292 @default.
• W4293771029 hasLocation W42937710293 @default.
• W4293771029 hasOpenAccess W4293771029 @default.
• W4293771029 hasPrimaryLocation W42937710291 @default.
• W4293771029 hasRelatedWork W136411592 @default.
• W4293771029 hasRelatedWork W2020898191 @default.
• W4293771029 hasRelatedWork W2032853726 @default.
• W4293771029 hasRelatedWork W2049364475 @default.
• W4293771029 hasRelatedWork W2102925359 @default.
• W4293771029 hasRelatedWork W2128269008 @default.
• W4293771029 hasRelatedWork W2388730008 @default.
• W4293771029 hasRelatedWork W2943224612 @default.
• W4293771029 hasRelatedWork W4286829519 @default.
• W4293771029 hasRelatedWork W4366111355 @default.

• next