FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4293776384> ?p ?o ?g. }

• W4293776384 endingPage "259" @default.
• W4293776384 startingPage "259" @default.
• W4293776384 abstract "Background and Aims : Adrenal lesions are increasingly recognized as a potential cause of hyperaldosteronism and hypercortisolism, with adverse metabolic effects potentially increasing the risk of cardiovascular events. We examined the association of adrenal abnormalities with ischemic stroke and intracerebral hemorrhage (ICH).Methods: We performed a cross-sectional study using data from the Cornell Acute Stroke Academic Registry (CAESAR), which includes patients with ischemic stroke and ICH at our medical center since 2018. As controls, we included randomly selected patients hospitalized with traumatic brain injury (TBI). We included patients who had undergone an abdominal CT with and without contrast. Imaging reports were reviewed for any mentions of adrenal abnormalities by reviewers blinded to the study hypothesis. We calculated prevalence rates of adrenal abnormalities by group and used logistic regression models, adjusted for demographics and vascular risk factors, to evaluate the association of adrenal abnormalities with ischemic stroke and ICH, in reference to those control patients with TBI.Results: Among 75 IS patients, 75 ICH patients, and 75 TBI controls, adrenal abnormalities were found in 12% of the TBI patients, 13% of the ICH patients, and 15% of the IS patients (P = 0.89). In multiple logistic regression models, adrenal abnormalities were not associated with ischemic stroke (OR, 1.1; 95% CI, 0.4-3.0) or ICH (OR, 1.1; 95% CI, 0.4-2.9).Conclusions: We found that patients with ischemic stroke or ICH did not have a higher prevalence of adrenal abnormalities than control patients. Future studies may be warranted to further investigate the role of occult hypercortisolism and hyperaldosteronism in stroke risk. Background and Aims : Adrenal lesions are increasingly recognized as a potential cause of hyperaldosteronism and hypercortisolism, with adverse metabolic effects potentially increasing the risk of cardiovascular events. We examined the association of adrenal abnormalities with ischemic stroke and intracerebral hemorrhage (ICH). Methods: We performed a cross-sectional study using data from the Cornell Acute Stroke Academic Registry (CAESAR), which includes patients with ischemic stroke and ICH at our medical center since 2018. As controls, we included randomly selected patients hospitalized with traumatic brain injury (TBI). We included patients who had undergone an abdominal CT with and without contrast. Imaging reports were reviewed for any mentions of adrenal abnormalities by reviewers blinded to the study hypothesis. We calculated prevalence rates of adrenal abnormalities by group and used logistic regression models, adjusted for demographics and vascular risk factors, to evaluate the association of adrenal abnormalities with ischemic stroke and ICH, in reference to those control patients with TBI. Results: Among 75 IS patients, 75 ICH patients, and 75 TBI controls, adrenal abnormalities were found in 12% of the TBI patients, 13% of the ICH patients, and 15% of the IS patients (P = 0.89). In multiple logistic regression models, adrenal abnormalities were not associated with ischemic stroke (OR, 1.1; 95% CI, 0.4-3.0) or ICH (OR, 1.1; 95% CI, 0.4-2.9). Conclusions: We found that patients with ischemic stroke or ICH did not have a higher prevalence of adrenal abnormalities than control patients. Future studies may be warranted to further investigate the role of occult hypercortisolism and hyperaldosteronism in stroke risk." @default.
• W4293776384 created "2022-08-31" @default.
• W4293776384 creator A5034952151 @default.
• W4293776384 creator A5051669270 @default.
• W4293776384 creator A5064898272 @default.
• W4293776384 date "2022-08-01" @default.
• W4293776384 modified "2023-09-26" @default.
• W4293776384 title "Adrenal abnormalities and stroke" @default.
• W4293776384 doi "https://doi.org/10.1016/j.atherosclerosis.2022.06.981" @default.
• W4293776384 hasPublicationYear "2022" @default.
• W4293776384 type Work @default.
• W4293776384 citedByCount "0" @default.
• W4293776384 crossrefType "journal-article" @default.
• W4293776384 hasAuthorship W4293776384A5034952151 @default.
• W4293776384 hasAuthorship W4293776384A5051669270 @default.
• W4293776384 hasAuthorship W4293776384A5064898272 @default.
• W4293776384 hasBestOaLocation W42937763841 @default.
• W4293776384 hasConcept C126322002 @default.
• W4293776384 hasConcept C127413603 @default.
• W4293776384 hasConcept C2776292634 @default.
• W4293776384 hasConcept C2777094939 @default.
• W4293776384 hasConcept C2777736543 @default.
• W4293776384 hasConcept C2778525890 @default.
• W4293776384 hasConcept C2780645631 @default.
• W4293776384 hasConcept C3020199598 @default.
• W4293776384 hasConcept C541997718 @default.
• W4293776384 hasConcept C71924100 @default.
• W4293776384 hasConcept C78519656 @default.
• W4293776384 hasConceptScore W4293776384C126322002 @default.
• W4293776384 hasConceptScore W4293776384C127413603 @default.
• W4293776384 hasConceptScore W4293776384C2776292634 @default.
• W4293776384 hasConceptScore W4293776384C2777094939 @default.
• W4293776384 hasConceptScore W4293776384C2777736543 @default.
• W4293776384 hasConceptScore W4293776384C2778525890 @default.
• W4293776384 hasConceptScore W4293776384C2780645631 @default.
• W4293776384 hasConceptScore W4293776384C3020199598 @default.
• W4293776384 hasConceptScore W4293776384C541997718 @default.
• W4293776384 hasConceptScore W4293776384C71924100 @default.
• W4293776384 hasConceptScore W4293776384C78519656 @default.
• W4293776384 hasLocation W42937763841 @default.
• W4293776384 hasOpenAccess W4293776384 @default.
• W4293776384 hasPrimaryLocation W42937763841 @default.
• W4293776384 hasRelatedWork W1560217929 @default.
• W4293776384 hasRelatedWork W2227771290 @default.
• W4293776384 hasRelatedWork W2396404771 @default.
• W4293776384 hasRelatedWork W2412666588 @default.
• W4293776384 hasRelatedWork W2769279457 @default.
• W4293776384 hasRelatedWork W2885680104 @default.
• W4293776384 hasRelatedWork W2954773974 @default.
• W4293776384 hasRelatedWork W4206063463 @default.
• W4293776384 hasRelatedWork W2245259410 @default.
• W4293776384 hasRelatedWork W2396691084 @default.
• W4293776384 hasVolume "355" @default.
• W4293776384 isParatext "false" @default.
• W4293776384 isRetracted "false" @default.
• W4293776384 workType "article" @default.