FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4293792855> ?p ?o ?g. }

• W4293792855 endingPage "360" @default.
• W4293792855 startingPage "353" @default.
• W4293792855 abstract "Abstract Background A number of genes have been implicated in rare familial syndromes which have migraine as part of their phenotype but these genes have not previously been implicated in the common form of migraine. Methods Among exome‐sequenced participants in the UK Biobank, we identified 7194 migraine cases with the remaining 193,433 participants classified as controls. We investigated rare variants in 10 genes previously reported to be implicated in conditions with migraine as a prominent part of the phenotype and carried out gene‐ and variant‐based tests for association. Results We found no evidence for association of these genes or variants with the common form of migraine seen in our subjects. In particular, a frameshift variant in KCNK18 , p.(Phe139Trpfs*24), which had been shown to segregate with migraine with aura in a multiply affected pedigree, was found in 196 (0.10%) controls as well as in 10 (0.14%) cases ( χ 2 = 0.96, 1 df, p = 0.33). Conclusions Since there is no other reported evidence to implicate KCNK18 , we conclude that this gene and its product, TRESK, should no longer be regarded as being involved in migraine aetiology. Overall, we do not find that rare, functional variants in genes previously implicated to be involved in familial syndromes including migraine as part of the phenotype make a contribution to the commoner forms of migraine observed in this population." @default.
• W4293792855 created "2022-08-31" @default.
• W4293792855 creator A5014321733 @default.
• W4293792855 creator A5063408005 @default.
• W4293792855 date "2022-08-31" @default.
• W4293792855 modified "2023-09-25" @default.
• W4293792855 title "Study of variants in genes implicated in rare familial migraine syndromes and their association with migraine in 200,000 exome‐sequenced UK Biobank participants" @default.
• W4293792855 cites W1563940013 @default.
• W4293792855 cites W1583710296 @default.
• W4293792855 cites W1980740976 @default.
• W4293792855 cites W1995839968 @default.
• W4293792855 cites W2000480163 @default.
• W4293792855 cites W2001308135 @default.
• W4293792855 cites W2003262566 @default.
• W4293792855 cites W2008180402 @default.
• W4293792855 cites W2012968975 @default.
• W4293792855 cites W2021556801 @default.
• W4293792855 cites W2025197615 @default.
• W4293792855 cites W2035274838 @default.
• W4293792855 cites W2037879072 @default.
• W4293792855 cites W2040446076 @default.
• W4293792855 cites W2041216483 @default.
• W4293792855 cites W2051573724 @default.
• W4293792855 cites W2058494375 @default.
• W4293792855 cites W2067558876 @default.
• W4293792855 cites W2069107563 @default.
• W4293792855 cites W2075172390 @default.
• W4293792855 cites W2078216779 @default.
• W4293792855 cites W2084565925 @default.
• W4293792855 cites W2099085143 @default.
• W4293792855 cites W2111785629 @default.
• W4293792855 cites W2122708962 @default.
• W4293792855 cites W2130088345 @default.
• W4293792855 cites W2163946681 @default.
• W4293792855 cites W2172111073 @default.
• W4293792855 cites W2175680907 @default.
• W4293792855 cites W2284253967 @default.
• W4293792855 cites W2417483443 @default.
• W4293792855 cites W2586533881 @default.
• W4293792855 cites W2765229680 @default.
• W4293792855 cites W2896138545 @default.
• W4293792855 cites W2904553519 @default.
• W4293792855 cites W2950188004 @default.
• W4293792855 cites W2951673592 @default.
• W4293792855 cites W2958139047 @default.
• W4293792855 cites W3038620779 @default.
• W4293792855 cites W3045706810 @default.
• W4293792855 cites W3046118122 @default.
• W4293792855 cites W3094946456 @default.
• W4293792855 cites W3120624632 @default.
• W4293792855 cites W3157665306 @default.
• W4293792855 cites W3158321631 @default.
• W4293792855 cites W3177160312 @default.
• W4293792855 cites W3191451220 @default.
• W4293792855 cites W3205828926 @default.
• W4293792855 cites W4225281509 @default.
• W4293792855 cites W4256431561 @default.
• W4293792855 cites W4293792855 @default.
• W4293792855 doi "https://doi.org/10.1111/ahg.12484" @default.
• W4293792855 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36044383" @default.
• W4293792855 hasPublicationYear "2022" @default.
• W4293792855 type Work @default.
• W4293792855 citedByCount "3" @default.
• W4293792855 countsByYear W42937928552022 @default.
• W4293792855 countsByYear W42937928552023 @default.
• W4293792855 crossrefType "journal-article" @default.
• W4293792855 hasAuthorship W4293792855A5014321733 @default.
• W4293792855 hasAuthorship W4293792855A5063408005 @default.
• W4293792855 hasBestOaLocation W42937928551 @default.
• W4293792855 hasConcept C104317684 @default.
• W4293792855 hasConcept C10590036 @default.
• W4293792855 hasConcept C116567970 @default.
• W4293792855 hasConcept C126322002 @default.
• W4293792855 hasConcept C127716648 @default.
• W4293792855 hasConcept C135763542 @default.
• W4293792855 hasConcept C137627325 @default.
• W4293792855 hasConcept C142724271 @default.
• W4293792855 hasConcept C153209595 @default.
• W4293792855 hasConcept C16671776 @default.
• W4293792855 hasConcept C186413461 @default.
• W4293792855 hasConcept C2776497919 @default.
• W4293792855 hasConcept C2777350023 @default.
• W4293792855 hasConcept C2778042195 @default.
• W4293792855 hasConcept C2778541695 @default.
• W4293792855 hasConcept C2908647359 @default.
• W4293792855 hasConcept C29906990 @default.
• W4293792855 hasConcept C54355233 @default.
• W4293792855 hasConcept C60644358 @default.
• W4293792855 hasConcept C71924100 @default.
• W4293792855 hasConcept C86803240 @default.
• W4293792855 hasConcept C99454951 @default.
• W4293792855 hasConceptScore W4293792855C104317684 @default.
• W4293792855 hasConceptScore W4293792855C10590036 @default.
• W4293792855 hasConceptScore W4293792855C116567970 @default.
• W4293792855 hasConceptScore W4293792855C126322002 @default.
• W4293792855 hasConceptScore W4293792855C127716648 @default.
• W4293792855 hasConceptScore W4293792855C135763542 @default.
• W4293792855 hasConceptScore W4293792855C137627325 @default.

• next