Matches in SemOpenAlex for { <https://semopenalex.org/work/W4293792886> ?p ?o ?g. }
- W4293792886 abstract "The orchid Dendrobium officinale grows throughout southeast China and southeast Asian countries and is used to treat inflammation and diabetes in traditional Chinese medicine. Tie pi feng dou is a well-known traditional Chinese medicine made from the dried D. officinale stems. Processing alters the physicochemical properties of TPFD; however, it is unclear how processing affects the quality and medicinal value of this plant. Here, we analyzed and compared the chemical composition of fresh stems of D. officinale and TPFD and explored possible explanations for the enhanced medicinal efficacy of processed D. officinale stems using qualitative and quantitative methods. To identify the components of FSD and TPFD, we used ultra-high-performance liquid chromatography combined with mass spectrometry in negative and positive ion modes and interpreted the data using the Human Metabolome Database and multivariate statistical analysis. We detected 23,709 peaks and identified 2352 metabolites; 370 of these metabolites were differentially abundant between FSD and TPFD (245 more abundant in TPFD than in FSD, and 125 less abundant), including organooxygen compounds, prenol lipids, flavonoids, carboxylic acids and their derivatives, and fatty acyls. Of these, 43 chemical markers clearly distinguished between FSD and TPFD samples, as confirmed using orthogonal partial least squares discriminant analysis. A pharmacological activity analysis showed that, compared with FSD, TPFD had significantly higher levels of some metabolites with anti-inflammatory activity, consistent with its use to treat inflammation. In addition to revealing the basis of the medicinal efficacy of TPFD, this study supports the benefits of the traditional usage of D. officinale." @default.
- W4293792886 created "2022-08-31" @default.
- W4293792886 creator A5017834988 @default.
- W4293792886 creator A5031844861 @default.
- W4293792886 creator A5043202295 @default.
- W4293792886 creator A5048153562 @default.
- W4293792886 creator A5074028169 @default.
- W4293792886 creator A5075512825 @default.
- W4293792886 creator A5079846306 @default.
- W4293792886 date "2022-08-31" @default.
- W4293792886 modified "2023-10-18" @default.
- W4293792886 title "Traditional processing increases biological activities of Dendrobium offificinale Kimura et. Migo in Southeast Yunnan, China" @default.
- W4293792886 cites W107102103 @default.
- W4293792886 cites W1893261346 @default.
- W4293792886 cites W1976433713 @default.
- W4293792886 cites W1986185545 @default.
- W4293792886 cites W1990188155 @default.
- W4293792886 cites W1991412491 @default.
- W4293792886 cites W1994695106 @default.
- W4293792886 cites W1999995146 @default.
- W4293792886 cites W2008803452 @default.
- W4293792886 cites W2010854781 @default.
- W4293792886 cites W2022503973 @default.
- W4293792886 cites W2025565467 @default.
- W4293792886 cites W2031495844 @default.
- W4293792886 cites W2034654996 @default.
- W4293792886 cites W2035935177 @default.
- W4293792886 cites W2044182454 @default.
- W4293792886 cites W2047688594 @default.
- W4293792886 cites W2052084403 @default.
- W4293792886 cites W2055447253 @default.
- W4293792886 cites W2058917612 @default.
- W4293792886 cites W2067904003 @default.
- W4293792886 cites W2071441076 @default.
- W4293792886 cites W2079559560 @default.
- W4293792886 cites W2084599031 @default.
- W4293792886 cites W2085006345 @default.
- W4293792886 cites W2086558654 @default.
- W4293792886 cites W2087669579 @default.
- W4293792886 cites W2116060738 @default.
- W4293792886 cites W2116687544 @default.
- W4293792886 cites W2127965500 @default.
- W4293792886 cites W2139314335 @default.
- W4293792886 cites W2152129598 @default.
- W4293792886 cites W2159518181 @default.
- W4293792886 cites W2165639457 @default.
- W4293792886 cites W2425956743 @default.
- W4293792886 cites W2583898443 @default.
- W4293792886 cites W2604663826 @default.
- W4293792886 cites W2731021506 @default.
- W4293792886 cites W2760069944 @default.
- W4293792886 cites W2888162511 @default.
- W4293792886 cites W2891221466 @default.
- W4293792886 cites W2912254148 @default.
- W4293792886 cites W2915165252 @default.
- W4293792886 cites W2927294060 @default.
- W4293792886 cites W2951227962 @default.
- W4293792886 cites W2971080678 @default.
- W4293792886 cites W2981657939 @default.
- W4293792886 cites W2995504322 @default.
- W4293792886 cites W2999159345 @default.
- W4293792886 cites W3005320477 @default.
- W4293792886 cites W3013748221 @default.
- W4293792886 cites W3016317048 @default.
- W4293792886 cites W3034993571 @default.
- W4293792886 cites W3035763624 @default.
- W4293792886 cites W3088519819 @default.
- W4293792886 cites W3092126089 @default.
- W4293792886 cites W3099394054 @default.
- W4293792886 cites W3111833476 @default.
- W4293792886 cites W3112544602 @default.
- W4293792886 cites W3127343642 @default.
- W4293792886 cites W3128855717 @default.
- W4293792886 cites W3135174721 @default.
- W4293792886 cites W3136005745 @default.
- W4293792886 cites W3137217201 @default.
- W4293792886 cites W3137611359 @default.
- W4293792886 cites W3138438498 @default.
- W4293792886 cites W3148719623 @default.
- W4293792886 cites W3150292783 @default.
- W4293792886 cites W3154770664 @default.
- W4293792886 cites W3163149298 @default.
- W4293792886 cites W3167269306 @default.
- W4293792886 cites W3168450008 @default.
- W4293792886 cites W3171860409 @default.
- W4293792886 cites W3173784586 @default.
- W4293792886 cites W3186201350 @default.
- W4293792886 cites W3192848476 @default.
- W4293792886 cites W4206446364 @default.
- W4293792886 cites W4244265877 @default.
- W4293792886 doi "https://doi.org/10.1038/s41598-022-17628-8" @default.
- W4293792886 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36045147" @default.
- W4293792886 hasPublicationYear "2022" @default.
- W4293792886 type Work @default.
- W4293792886 citedByCount "1" @default.
- W4293792886 countsByYear W42937928862022 @default.
- W4293792886 crossrefType "journal-article" @default.
- W4293792886 hasAuthorship W4293792886A5017834988 @default.
- W4293792886 hasAuthorship W4293792886A5031844861 @default.
- W4293792886 hasAuthorship W4293792886A5043202295 @default.