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- W4293799746 abstract "Abstract Evidence for a sister relationship between Xenacoelomorpha and Ambulacraria (Xenambulacraria) has revived the longstanding debate surrounding the complexity of the Urdeuterostomian and Urbilaterian ancestors and has led to a reassessment of early bilaterian features. Employing whole organism single-cell RNA-seq in the marine xenacoelomorph worm Xenoturbella bocki , we show that Xenambulacrarian nerve nets share regulatory features and a peptidergic identity with those found in cnidarians and protostomes. We also suggest that Xenacoelomorpha muscles are likely to have evolved their “smooth” phenotype convergently. Furthermore, we identify pigmented cells as a potential synapomorphy of the Xenambulacraria. Taken together, these data are consistent with a simplification from an ancestral urbilaterian/urdeuterostomian body plan and a non-centralized nerve net, minimally differentiated contractile cells and evidence of deuterostome cell-type synapomorphies." @default.
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- W4293799746 date "2022-08-18" @default.
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- W4293799746 title "Single cell atlas of <i>Xenoturbella bocki</i> highlights the limited cell-type complexity of a non-vertebrate deuterostome lineage" @default.
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- W4293799746 doi "https://doi.org/10.1101/2022.08.18.504214" @default.
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