Matches in SemOpenAlex for { <https://semopenalex.org/work/W4294200703> ?p ?o ?g. }
Showing items 1 to 76 of
76
with 100 items per page.
- W4294200703 endingPage "S173" @default.
- W4294200703 startingPage "S172" @default.
- W4294200703 abstract "Introduction Traumatic brain injury (TBI) may alter dementia progression, although co-occurring neuropsychiatric symptoms (NPS) have received less attention. The mild behavioral impairment (MBI) construct relates NPS to underlying neural circuit disruptions, representing an important area of inquiry regarding TBI and dementia. Objectives (1) to examine the influence of prior TBI history (preceding study enrollment) on MBI incidence in all-cause dementia (prior to dementia diagnosis, i.e. MBI’s original definition) and (2) to utilize MBI domains as a construct for examining the influence of TBI on related NPS across the course of dementia onset and progression. Methods Using National Alzheimer’s Coordinating Center data, individuals progressing from normal cognition to all-cause dementia over 7.6±3.0 years were studied to estimate MBI incidence and symptom domains in 124 participants with prior TBI history compared to 822 without. Results Moderate-severe TBI was associated with the social inappropriateness MBI domain (OR adj. =4.034; p =0.024) prior to dementia onset, and the abnormal perception/thought content domain looking across dementia progression (HR adj. =3.703, p =0.005). TBI (all severities) was associated with the decreased motivation domain looking throughout dementia progression (HR adj. =1.546, p =0.014). Conclusions TBI history is associated with particular MBI domains prior to onset and throughout progression of dementia. Understanding TBI’s impact on inter-related NPS may help elucidate underlying neuropathology. Disclosure No significant relationships." @default.
- W4294200703 created "2022-09-02" @default.
- W4294200703 creator A5000988125 @default.
- W4294200703 creator A5006781690 @default.
- W4294200703 creator A5016370551 @default.
- W4294200703 creator A5017213987 @default.
- W4294200703 creator A5023971877 @default.
- W4294200703 creator A5044170742 @default.
- W4294200703 creator A5048533884 @default.
- W4294200703 creator A5067475767 @default.
- W4294200703 creator A5081384802 @default.
- W4294200703 creator A5089006898 @default.
- W4294200703 date "2022-06-01" @default.
- W4294200703 modified "2023-09-27" @default.
- W4294200703 title "Traumatic brain injury alters presentation of mild behavioral impairment domains across progression of all-cause dementia" @default.
- W4294200703 doi "https://doi.org/10.1192/j.eurpsy.2022.458" @default.
- W4294200703 hasPublicationYear "2022" @default.
- W4294200703 type Work @default.
- W4294200703 citedByCount "0" @default.
- W4294200703 crossrefType "journal-article" @default.
- W4294200703 hasAuthorship W4294200703A5000988125 @default.
- W4294200703 hasAuthorship W4294200703A5006781690 @default.
- W4294200703 hasAuthorship W4294200703A5016370551 @default.
- W4294200703 hasAuthorship W4294200703A5017213987 @default.
- W4294200703 hasAuthorship W4294200703A5023971877 @default.
- W4294200703 hasAuthorship W4294200703A5044170742 @default.
- W4294200703 hasAuthorship W4294200703A5048533884 @default.
- W4294200703 hasAuthorship W4294200703A5067475767 @default.
- W4294200703 hasAuthorship W4294200703A5081384802 @default.
- W4294200703 hasAuthorship W4294200703A5089006898 @default.
- W4294200703 hasBestOaLocation W42942007031 @default.
- W4294200703 hasConcept C118552586 @default.
- W4294200703 hasConcept C120665830 @default.
- W4294200703 hasConcept C121332964 @default.
- W4294200703 hasConcept C126322002 @default.
- W4294200703 hasConcept C15744967 @default.
- W4294200703 hasConcept C2779134260 @default.
- W4294200703 hasConcept C2779483572 @default.
- W4294200703 hasConcept C2780130745 @default.
- W4294200703 hasConcept C2781017439 @default.
- W4294200703 hasConcept C61511704 @default.
- W4294200703 hasConcept C70410870 @default.
- W4294200703 hasConcept C71924100 @default.
- W4294200703 hasConceptScore W4294200703C118552586 @default.
- W4294200703 hasConceptScore W4294200703C120665830 @default.
- W4294200703 hasConceptScore W4294200703C121332964 @default.
- W4294200703 hasConceptScore W4294200703C126322002 @default.
- W4294200703 hasConceptScore W4294200703C15744967 @default.
- W4294200703 hasConceptScore W4294200703C2779134260 @default.
- W4294200703 hasConceptScore W4294200703C2779483572 @default.
- W4294200703 hasConceptScore W4294200703C2780130745 @default.
- W4294200703 hasConceptScore W4294200703C2781017439 @default.
- W4294200703 hasConceptScore W4294200703C61511704 @default.
- W4294200703 hasConceptScore W4294200703C70410870 @default.
- W4294200703 hasConceptScore W4294200703C71924100 @default.
- W4294200703 hasIssue "S1" @default.
- W4294200703 hasLocation W42942007031 @default.
- W4294200703 hasLocation W42942007032 @default.
- W4294200703 hasOpenAccess W4294200703 @default.
- W4294200703 hasPrimaryLocation W42942007031 @default.
- W4294200703 hasRelatedWork W1580426574 @default.
- W4294200703 hasRelatedWork W1609112731 @default.
- W4294200703 hasRelatedWork W2020110948 @default.
- W4294200703 hasRelatedWork W2275480158 @default.
- W4294200703 hasRelatedWork W2526769090 @default.
- W4294200703 hasRelatedWork W2748952813 @default.
- W4294200703 hasRelatedWork W2899084033 @default.
- W4294200703 hasRelatedWork W2973073117 @default.
- W4294200703 hasRelatedWork W4238089809 @default.
- W4294200703 hasRelatedWork W4285161914 @default.
- W4294200703 hasVolume "65" @default.
- W4294200703 isParatext "false" @default.
- W4294200703 isRetracted "false" @default.
- W4294200703 workType "article" @default.