Matches in SemOpenAlex for { <https://semopenalex.org/work/W4294225472> ?p ?o ?g. }
- W4294225472 abstract "As an economically important fish, Opsariichthys bidens has obvious sexual dimorphism and strong reproductive capacity, but no epigenetics study can well explain its phenotypic variations. In recent years, many microRNAs involved in the regulation of reproductive development have been explored. In this study, the small RNA libraries of O. bidens on the testis and ovary were constructed and sequenced. A total of 295 known miRNAs were obtained and 100 novel miRNAs were predicted. By comparing testis and ovary libraries, 115 differentially expressed (DE) miRNAs were selected, of which 53 were up-regulated and 62 were down-regulated. A total of 64 GO items (padj < 0.01) and 206 KEGG pathways (padj < 0.01) were enriched in the target gene of miRNA. After that, the expression levels of nine DE miRNAs, including let-7a, miR-146b, miR-18c, miR-202-5p, miR-135c, miR-9-5p, miR-34c-3p, miR-460-5p and miR-338 were verified by qRT-PCR. Furthermore, bidirectional prediction of DE miRNAs and sex-related genes was carried out and the targeting correlation between miR-9-5p and nanos1 was verified by Dual-Luciferase reporter assay. Our findings identified the differentially expressed miRNA and paved the way to new possibilities for the follow-up study on the mechanism of miRNA-mRNA interaction in the gonads of O. bidens." @default.
- W4294225472 created "2022-09-02" @default.
- W4294225472 creator A5009008688 @default.
- W4294225472 creator A5038182119 @default.
- W4294225472 creator A5060612200 @default.
- W4294225472 creator A5061794553 @default.
- W4294225472 creator A5064590799 @default.
- W4294225472 creator A5074074463 @default.
- W4294225472 creator A5078753498 @default.
- W4294225472 creator A5084900083 @default.
- W4294225472 date "2022-09-02" @default.
- W4294225472 modified "2023-09-27" @default.
- W4294225472 title "Identification and expression analysis of sex biased miRNAs in chinese hook snout carp Opsariichthys bidens" @default.
- W4294225472 cites W1513515886 @default.
- W4294225472 cites W1951960792 @default.
- W4294225472 cites W1971546287 @default.
- W4294225472 cites W2003706184 @default.
- W4294225472 cites W2005440577 @default.
- W4294225472 cites W2010905878 @default.
- W4294225472 cites W2018784772 @default.
- W4294225472 cites W2022822215 @default.
- W4294225472 cites W2049868101 @default.
- W4294225472 cites W2050497323 @default.
- W4294225472 cites W2054382229 @default.
- W4294225472 cites W2055043387 @default.
- W4294225472 cites W2070571588 @default.
- W4294225472 cites W2073875157 @default.
- W4294225472 cites W2074695498 @default.
- W4294225472 cites W2082041132 @default.
- W4294225472 cites W2106029962 @default.
- W4294225472 cites W2113209482 @default.
- W4294225472 cites W2120456037 @default.
- W4294225472 cites W2121148429 @default.
- W4294225472 cites W2124050695 @default.
- W4294225472 cites W2130305733 @default.
- W4294225472 cites W2149598250 @default.
- W4294225472 cites W2150014745 @default.
- W4294225472 cites W2158381555 @default.
- W4294225472 cites W2339291854 @default.
- W4294225472 cites W2512939707 @default.
- W4294225472 cites W2737215659 @default.
- W4294225472 cites W2754466733 @default.
- W4294225472 cites W2761069052 @default.
- W4294225472 cites W2767125463 @default.
- W4294225472 cites W2781913855 @default.
- W4294225472 cites W2790449507 @default.
- W4294225472 cites W2791208527 @default.
- W4294225472 cites W2897730617 @default.
- W4294225472 cites W2900597665 @default.
- W4294225472 cites W2971225170 @default.
- W4294225472 cites W2990778209 @default.
- W4294225472 cites W3024518980 @default.
- W4294225472 cites W3025509547 @default.
- W4294225472 cites W3031816223 @default.
- W4294225472 cites W3035938571 @default.
- W4294225472 cites W3042055098 @default.
- W4294225472 cites W3135367910 @default.
- W4294225472 cites W3153761641 @default.
- W4294225472 cites W3159552789 @default.
- W4294225472 cites W3176566942 @default.
- W4294225472 cites W3215001587 @default.
- W4294225472 cites W4206635806 @default.
- W4294225472 cites W4211064852 @default.
- W4294225472 cites W4214934855 @default.
- W4294225472 cites W4280507728 @default.
- W4294225472 cites W4285801163 @default.
- W4294225472 doi "https://doi.org/10.3389/fgene.2022.990683" @default.
- W4294225472 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36118893" @default.
- W4294225472 hasPublicationYear "2022" @default.
- W4294225472 type Work @default.
- W4294225472 citedByCount "1" @default.
- W4294225472 countsByYear W42942254722022 @default.
- W4294225472 crossrefType "journal-article" @default.
- W4294225472 hasAuthorship W4294225472A5009008688 @default.
- W4294225472 hasAuthorship W4294225472A5038182119 @default.
- W4294225472 hasAuthorship W4294225472A5060612200 @default.
- W4294225472 hasAuthorship W4294225472A5061794553 @default.
- W4294225472 hasAuthorship W4294225472A5064590799 @default.
- W4294225472 hasAuthorship W4294225472A5074074463 @default.
- W4294225472 hasAuthorship W4294225472A5078753498 @default.
- W4294225472 hasAuthorship W4294225472A5084900083 @default.
- W4294225472 hasBestOaLocation W42942254721 @default.
- W4294225472 hasConcept C104317684 @default.
- W4294225472 hasConcept C145059251 @default.
- W4294225472 hasConcept C150194340 @default.
- W4294225472 hasConcept C152724338 @default.
- W4294225472 hasConcept C162317418 @default.
- W4294225472 hasConcept C2778324911 @default.
- W4294225472 hasConcept C41091548 @default.
- W4294225472 hasConcept C54355233 @default.
- W4294225472 hasConcept C70721500 @default.
- W4294225472 hasConcept C86803240 @default.
- W4294225472 hasConceptScore W4294225472C104317684 @default.
- W4294225472 hasConceptScore W4294225472C145059251 @default.
- W4294225472 hasConceptScore W4294225472C150194340 @default.
- W4294225472 hasConceptScore W4294225472C152724338 @default.
- W4294225472 hasConceptScore W4294225472C162317418 @default.
- W4294225472 hasConceptScore W4294225472C2778324911 @default.
- W4294225472 hasConceptScore W4294225472C41091548 @default.
- W4294225472 hasConceptScore W4294225472C54355233 @default.