Matches in SemOpenAlex for { <https://semopenalex.org/work/W4294335631> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W4294335631 endingPage "908" @default.
- W4294335631 startingPage "903" @default.
- W4294335631 abstract "Diffuse infiltrating gliomas are the most common malignant brain tumors in adults. The 2021 World Health Organization classification for CNS tumors (CNS5 WHO) has significantly altered the rules for classification and grading of diffuse gliomas. Clinicians, including neurology residents and neurologists, will have to consider the changes that include the introduction of new tumor types, allotting established tumor types to other groups and substituting previously essential morphological features for additional molecular markers. For example, in the current classification, glioblastoma is defined as isocitrate dehydrogenase (IDH)-wildtype, grade 4. Whereas, a grade 4 IDH-mutated astrocytic glioma is referred to as astrocytoma, IDH-mutated, grade 4. In addition, potential targeted treatments, based on the underlying molecular alterations, have become therapeutic options for diffuse gliomas. For clinicians, it is important to know the rationale for why these options are only available for specific tumors. Owing to the emphasis of molecular markers in the CNS5 WHO classification, interpretation of a pathology report and understanding of its clinical implications can be challenging. This review describes the most important molecular alterations in glioma, summarizes the recent changes in the CNS5 WHO classification for glioma, and presents a stepwise approach for trainees and neurologists to decipher a glioma pathology report. Additional information is summarized in eTable 1 (links.lww.com/WNL/C324)." @default.
- W4294335631 created "2022-09-02" @default.
- W4294335631 creator A5001441278 @default.
- W4294335631 creator A5006549117 @default.
- W4294335631 creator A5017575332 @default.
- W4294335631 creator A5028416358 @default.
- W4294335631 creator A5057811197 @default.
- W4294335631 date "2022-11-15" @default.
- W4294335631 modified "2023-09-26" @default.
- W4294335631 title "Opinion & Special Article: Glioma Classification" @default.
- W4294335631 cites W1988756388 @default.
- W4294335631 cites W2003601426 @default.
- W4294335631 cites W2075608121 @default.
- W4294335631 cites W2155706138 @default.
- W4294335631 cites W2588735165 @default.
- W4294335631 cites W2802818144 @default.
- W4294335631 cites W2891484912 @default.
- W4294335631 cites W2891763428 @default.
- W4294335631 cites W3014838714 @default.
- W4294335631 cites W3048230500 @default.
- W4294335631 cites W4211220688 @default.
- W4294335631 doi "https://doi.org/10.1212/wnl.0000000000201262" @default.
- W4294335631 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36240081" @default.
- W4294335631 hasPublicationYear "2022" @default.
- W4294335631 type Work @default.
- W4294335631 citedByCount "4" @default.
- W4294335631 countsByYear W42943356312023 @default.
- W4294335631 crossrefType "journal-article" @default.
- W4294335631 hasAuthorship W4294335631A5001441278 @default.
- W4294335631 hasAuthorship W4294335631A5006549117 @default.
- W4294335631 hasAuthorship W4294335631A5017575332 @default.
- W4294335631 hasAuthorship W4294335631A5028416358 @default.
- W4294335631 hasAuthorship W4294335631A5057811197 @default.
- W4294335631 hasBestOaLocation W42943356311 @default.
- W4294335631 hasConcept C104317684 @default.
- W4294335631 hasConcept C118552586 @default.
- W4294335631 hasConcept C127848430 @default.
- W4294335631 hasConcept C142724271 @default.
- W4294335631 hasConcept C143998085 @default.
- W4294335631 hasConcept C16568411 @default.
- W4294335631 hasConcept C181199279 @default.
- W4294335631 hasConcept C18903297 @default.
- W4294335631 hasConcept C2776194525 @default.
- W4294335631 hasConcept C2777150147 @default.
- W4294335631 hasConcept C2777286243 @default.
- W4294335631 hasConcept C2778227246 @default.
- W4294335631 hasConcept C2778880634 @default.
- W4294335631 hasConcept C2779130545 @default.
- W4294335631 hasConcept C501734568 @default.
- W4294335631 hasConcept C502942594 @default.
- W4294335631 hasConcept C55493867 @default.
- W4294335631 hasConcept C60644358 @default.
- W4294335631 hasConcept C71924100 @default.
- W4294335631 hasConcept C86803240 @default.
- W4294335631 hasConceptScore W4294335631C104317684 @default.
- W4294335631 hasConceptScore W4294335631C118552586 @default.
- W4294335631 hasConceptScore W4294335631C127848430 @default.
- W4294335631 hasConceptScore W4294335631C142724271 @default.
- W4294335631 hasConceptScore W4294335631C143998085 @default.
- W4294335631 hasConceptScore W4294335631C16568411 @default.
- W4294335631 hasConceptScore W4294335631C181199279 @default.
- W4294335631 hasConceptScore W4294335631C18903297 @default.
- W4294335631 hasConceptScore W4294335631C2776194525 @default.
- W4294335631 hasConceptScore W4294335631C2777150147 @default.
- W4294335631 hasConceptScore W4294335631C2777286243 @default.
- W4294335631 hasConceptScore W4294335631C2778227246 @default.
- W4294335631 hasConceptScore W4294335631C2778880634 @default.
- W4294335631 hasConceptScore W4294335631C2779130545 @default.
- W4294335631 hasConceptScore W4294335631C501734568 @default.
- W4294335631 hasConceptScore W4294335631C502942594 @default.
- W4294335631 hasConceptScore W4294335631C55493867 @default.
- W4294335631 hasConceptScore W4294335631C60644358 @default.
- W4294335631 hasConceptScore W4294335631C71924100 @default.
- W4294335631 hasConceptScore W4294335631C86803240 @default.
- W4294335631 hasIssue "20" @default.
- W4294335631 hasLocation W42943356311 @default.
- W4294335631 hasLocation W42943356312 @default.
- W4294335631 hasOpenAccess W4294335631 @default.
- W4294335631 hasPrimaryLocation W42943356311 @default.
- W4294335631 hasRelatedWork W2047852512 @default.
- W4294335631 hasRelatedWork W2081712124 @default.
- W4294335631 hasRelatedWork W2157219413 @default.
- W4294335631 hasRelatedWork W2170206357 @default.
- W4294335631 hasRelatedWork W3013369088 @default.
- W4294335631 hasRelatedWork W3030671992 @default.
- W4294335631 hasRelatedWork W4200111615 @default.
- W4294335631 hasRelatedWork W4241042114 @default.
- W4294335631 hasRelatedWork W4294335631 @default.
- W4294335631 hasRelatedWork W4327649170 @default.
- W4294335631 hasVolume "99" @default.
- W4294335631 isParatext "false" @default.
- W4294335631 isRetracted "false" @default.
- W4294335631 workType "article" @default.