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- W4294545098 abstract "In mammals, the complex interaction of neural, hormonal, and behavioral outputs from the suprachiasmatic nucleus (SCN) drives circadian expression of events, either directly or through coordination of the timing of peripheral oscillators. Melatonin, one of the endocrine output signals of the clock, provides the organism with circadian information and can be considered as an endogenous synchronizer, able to stabilize and reinforce circadian rhythms and to maintain their mutual phase‐relationship at the different levels of the circadian network. Moreover, exogenous melatonin, through an action on the circadian clock, affects all levels of the circadian network. The molecular mechanisms underlying this chronobiotic effect have also been investigated in rats. REV‐ERB α seems to be the initial molecular target." @default.
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- W4294545098 date "2006-01-01" @default.
- W4294545098 modified "2023-10-14" @default.
- W4294545098 title "Melatonin in the multi‐oscillatory mammalian circadian world" @default.
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- W4294545098 doi "https://doi.org/10.1080/07420520500482074" @default.
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