Matches in SemOpenAlex for { <https://semopenalex.org/work/W4294609462> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W4294609462 abstract "Hyperuricemia is a state in which the serum levels of uric acid (UA) are elevated. This study was to determine the roles of rosuvastatin in fasting blood glucose (FGB) and insulin levels in hyperuricemic rats.Thirty-six Sprague-Dawley (SD) rats were randomized divided into the control, model and rosuvastatin groups: the control was given no intervention, the model group was established by administrating yeast extract powder and oxonic acid potassium salt, and the rosuvastatin group was given intravenous administration of rosuvastatin for 28 days in hyperuricemic rats. Serum uric acid (SUA), fasting blood glucose (FBG), fasting blood insulin (FBI), glutamic acid decarboxylase antibody (GADA), oral glucose tolerance test (OGTT) levels, and the ultrastructure of pancreatic β-cells were measured. Also, homeostasis model assessment of insulin resistance (HOMA-IR) scores was computed in three groups.Compared to the model group, SUA were decreased, while the FBG, GADA, OGTT and HOMA-IR at week 4 were significantly increased in rosuvastatin group. However, FBI was not significantly changed between three groups. It was also showed that the structure of pancreatic β-cells was damaged and the number of β-cells was changed in hyperuricemic rats while they were aggravated in rosuvastatin group.Rosuvastatin has roles in inducing FGB, GADA, OGTT and pancreatic β-cells damage in hyperuricemic rats." @default.
- W4294609462 created "2022-09-05" @default.
- W4294609462 creator A5017773158 @default.
- W4294609462 creator A5024307448 @default.
- W4294609462 creator A5036276153 @default.
- W4294609462 creator A5044233960 @default.
- W4294609462 creator A5076045712 @default.
- W4294609462 creator A5085176509 @default.
- W4294609462 creator A5088685470 @default.
- W4294609462 date "2022-09-05" @default.
- W4294609462 modified "2023-10-06" @default.
- W4294609462 title "Effects of rosuvastatin on serum glucose and insulin in hyperuricemic rats" @default.
- W4294609462 cites W1515706775 @default.
- W4294609462 cites W1855528199 @default.
- W4294609462 cites W1878784224 @default.
- W4294609462 cites W1967494888 @default.
- W4294609462 cites W1969080742 @default.
- W4294609462 cites W1972566273 @default.
- W4294609462 cites W1976531866 @default.
- W4294609462 cites W1981184598 @default.
- W4294609462 cites W1999320125 @default.
- W4294609462 cites W2040286046 @default.
- W4294609462 cites W2061274318 @default.
- W4294609462 cites W2082915859 @default.
- W4294609462 cites W2095747032 @default.
- W4294609462 cites W2103108681 @default.
- W4294609462 cites W2115169717 @default.
- W4294609462 cites W2132396935 @default.
- W4294609462 cites W2137983259 @default.
- W4294609462 cites W2162309758 @default.
- W4294609462 cites W2164750952 @default.
- W4294609462 cites W2275083056 @default.
- W4294609462 cites W2323976047 @default.
- W4294609462 cites W2607031541 @default.
- W4294609462 cites W2732885704 @default.
- W4294609462 cites W2889595609 @default.
- W4294609462 cites W2902545113 @default.
- W4294609462 cites W2929256153 @default.
- W4294609462 cites W2981531054 @default.
- W4294609462 cites W3046126074 @default.
- W4294609462 cites W3088105950 @default.
- W4294609462 cites W3098915518 @default.
- W4294609462 cites W4242868838 @default.
- W4294609462 cites W4254965081 @default.
- W4294609462 doi "https://doi.org/10.1186/s40360-022-00595-1" @default.
- W4294609462 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36064644" @default.
- W4294609462 hasPublicationYear "2022" @default.
- W4294609462 type Work @default.
- W4294609462 citedByCount "1" @default.
- W4294609462 countsByYear W42946094622023 @default.
- W4294609462 crossrefType "journal-article" @default.
- W4294609462 hasAuthorship W4294609462A5017773158 @default.
- W4294609462 hasAuthorship W4294609462A5024307448 @default.
- W4294609462 hasAuthorship W4294609462A5036276153 @default.
- W4294609462 hasAuthorship W4294609462A5044233960 @default.
- W4294609462 hasAuthorship W4294609462A5076045712 @default.
- W4294609462 hasAuthorship W4294609462A5085176509 @default.
- W4294609462 hasAuthorship W4294609462A5088685470 @default.
- W4294609462 hasBestOaLocation W42946094621 @default.
- W4294609462 hasConcept C126322002 @default.
- W4294609462 hasConcept C134018914 @default.
- W4294609462 hasConcept C2777391703 @default.
- W4294609462 hasConcept C2778110834 @default.
- W4294609462 hasConcept C2779306644 @default.
- W4294609462 hasConcept C2779721657 @default.
- W4294609462 hasConcept C2779881121 @default.
- W4294609462 hasConcept C2780499067 @default.
- W4294609462 hasConcept C71924100 @default.
- W4294609462 hasConceptScore W4294609462C126322002 @default.
- W4294609462 hasConceptScore W4294609462C134018914 @default.
- W4294609462 hasConceptScore W4294609462C2777391703 @default.
- W4294609462 hasConceptScore W4294609462C2778110834 @default.
- W4294609462 hasConceptScore W4294609462C2779306644 @default.
- W4294609462 hasConceptScore W4294609462C2779721657 @default.
- W4294609462 hasConceptScore W4294609462C2779881121 @default.
- W4294609462 hasConceptScore W4294609462C2780499067 @default.
- W4294609462 hasConceptScore W4294609462C71924100 @default.
- W4294609462 hasIssue "1" @default.
- W4294609462 hasLocation W42946094621 @default.
- W4294609462 hasLocation W42946094622 @default.
- W4294609462 hasLocation W42946094623 @default.
- W4294609462 hasLocation W42946094624 @default.
- W4294609462 hasOpenAccess W4294609462 @default.
- W4294609462 hasPrimaryLocation W42946094621 @default.
- W4294609462 hasRelatedWork W138803513 @default.
- W4294609462 hasRelatedWork W160302013 @default.
- W4294609462 hasRelatedWork W1986132654 @default.
- W4294609462 hasRelatedWork W2010140898 @default.
- W4294609462 hasRelatedWork W2042646534 @default.
- W4294609462 hasRelatedWork W2082140668 @default.
- W4294609462 hasRelatedWork W2165052328 @default.
- W4294609462 hasRelatedWork W2508323870 @default.
- W4294609462 hasRelatedWork W4234612679 @default.
- W4294609462 hasRelatedWork W30481545 @default.
- W4294609462 hasVolume "23" @default.
- W4294609462 isParatext "false" @default.
- W4294609462 isRetracted "false" @default.
- W4294609462 workType "article" @default.