Matches in SemOpenAlex for { <https://semopenalex.org/work/W4294617904> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W4294617904 abstract "Introduction We present a case of a patient with disseminated ACTH-secreting neuroendocrine neoplasm with biologic heterogeneity between a primary tumor and metastases. The diagnosis was obtained and multidisciplinary management was conducted with a positron emission tomography/computed tomography (PET/CT) scan with Gallium-68 [68Ga]-labeled dodecanetetraacetic acid-tyrosine-3-octreotate ([68Ga]-DOTA-TATE) and Fluor-18 [18F]-fluorodeoxyglucose ([18F]-FDG). Case report A PET/CT scan revealed a difference between [68Ga]-DOTA-TATE and [18F]-FDG uptake in primary tumor and several metastases. PET/CT showed high [18F]-FDG uptake and lack of [68Ga]-DOTA-TATE in the primary tumor, whereas both [68Ga]-DOTA-TATE and [18F]-FDG hyperaccumulation were identified in the majority of metastases. Despite positive [68Ga]-DOTA-TATE PET/CT, which is associated with high affinity with the somatostatin receptor 2 subtype, immunohistochemical examination revealed overexpression of the somatostatin receptor 5 subtype only. Perhaps, this explained the ineffectiveness of the treatment with “cold” somatostatin analogs. Conclusion This case had an aggressive clinical course, despite cytoreductive surgical treatment and somatostatin analog therapy. PET/CT imaging with two tracers is a molecular tool that demonstrates a biologic heterogeneity between a primary tumor and metastases and yields additional information that may influence the choice of the patient management strategy." @default.
- W4294617904 created "2022-09-05" @default.
- W4294617904 creator A5009480594 @default.
- W4294617904 creator A5039760547 @default.
- W4294617904 creator A5072213453 @default.
- W4294617904 creator A5076289673 @default.
- W4294617904 creator A5085840493 @default.
- W4294617904 date "2022-09-05" @default.
- W4294617904 modified "2023-10-18" @default.
- W4294617904 title "Dual-tracer PET/CT imaging to determine tumor heterogeneity in a patient with metastatic ACTH-secreting neuroendocrine neoplasm: A case report and literature review" @default.
- W4294617904 cites W1965014574 @default.
- W4294617904 cites W2001865343 @default.
- W4294617904 cites W2045188683 @default.
- W4294617904 cites W2052429698 @default.
- W4294617904 cites W2091025638 @default.
- W4294617904 cites W2132027833 @default.
- W4294617904 cites W2137142564 @default.
- W4294617904 cites W2138297302 @default.
- W4294617904 cites W2300351314 @default.
- W4294617904 cites W2341389582 @default.
- W4294617904 cites W2475291604 @default.
- W4294617904 cites W2530197215 @default.
- W4294617904 cites W2548317121 @default.
- W4294617904 cites W2592442081 @default.
- W4294617904 cites W2596879202 @default.
- W4294617904 cites W2886948720 @default.
- W4294617904 cites W2952695966 @default.
- W4294617904 cites W3025209256 @default.
- W4294617904 cites W3215281379 @default.
- W4294617904 cites W62521926 @default.
- W4294617904 doi "https://doi.org/10.3389/fendo.2022.958442" @default.
- W4294617904 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36133304" @default.
- W4294617904 hasPublicationYear "2022" @default.
- W4294617904 type Work @default.
- W4294617904 citedByCount "1" @default.
- W4294617904 countsByYear W42946179042022 @default.
- W4294617904 crossrefType "journal-article" @default.
- W4294617904 hasAuthorship W4294617904A5009480594 @default.
- W4294617904 hasAuthorship W4294617904A5039760547 @default.
- W4294617904 hasAuthorship W4294617904A5072213453 @default.
- W4294617904 hasAuthorship W4294617904A5076289673 @default.
- W4294617904 hasAuthorship W4294617904A5085840493 @default.
- W4294617904 hasBestOaLocation W42946179041 @default.
- W4294617904 hasConcept C121608353 @default.
- W4294617904 hasConcept C126322002 @default.
- W4294617904 hasConcept C126838900 @default.
- W4294617904 hasConcept C127077266 @default.
- W4294617904 hasConcept C142724271 @default.
- W4294617904 hasConcept C150903083 @default.
- W4294617904 hasConcept C207001950 @default.
- W4294617904 hasConcept C2775842073 @default.
- W4294617904 hasConcept C2776297358 @default.
- W4294617904 hasConcept C2777415128 @default.
- W4294617904 hasConcept C2779013556 @default.
- W4294617904 hasConcept C2779066768 @default.
- W4294617904 hasConcept C2779931791 @default.
- W4294617904 hasConcept C2780283643 @default.
- W4294617904 hasConcept C2989005 @default.
- W4294617904 hasConcept C71924100 @default.
- W4294617904 hasConcept C80115893 @default.
- W4294617904 hasConcept C86803240 @default.
- W4294617904 hasConceptScore W4294617904C121608353 @default.
- W4294617904 hasConceptScore W4294617904C126322002 @default.
- W4294617904 hasConceptScore W4294617904C126838900 @default.
- W4294617904 hasConceptScore W4294617904C127077266 @default.
- W4294617904 hasConceptScore W4294617904C142724271 @default.
- W4294617904 hasConceptScore W4294617904C150903083 @default.
- W4294617904 hasConceptScore W4294617904C207001950 @default.
- W4294617904 hasConceptScore W4294617904C2775842073 @default.
- W4294617904 hasConceptScore W4294617904C2776297358 @default.
- W4294617904 hasConceptScore W4294617904C2777415128 @default.
- W4294617904 hasConceptScore W4294617904C2779013556 @default.
- W4294617904 hasConceptScore W4294617904C2779066768 @default.
- W4294617904 hasConceptScore W4294617904C2779931791 @default.
- W4294617904 hasConceptScore W4294617904C2780283643 @default.
- W4294617904 hasConceptScore W4294617904C2989005 @default.
- W4294617904 hasConceptScore W4294617904C71924100 @default.
- W4294617904 hasConceptScore W4294617904C80115893 @default.
- W4294617904 hasConceptScore W4294617904C86803240 @default.
- W4294617904 hasLocation W42946179041 @default.
- W4294617904 hasLocation W42946179042 @default.
- W4294617904 hasLocation W42946179043 @default.
- W4294617904 hasOpenAccess W4294617904 @default.
- W4294617904 hasPrimaryLocation W42946179041 @default.
- W4294617904 hasRelatedWork W1978952912 @default.
- W4294617904 hasRelatedWork W2033480787 @default.
- W4294617904 hasRelatedWork W2060399302 @default.
- W4294617904 hasRelatedWork W2067772064 @default.
- W4294617904 hasRelatedWork W2148617171 @default.
- W4294617904 hasRelatedWork W3023258935 @default.
- W4294617904 hasRelatedWork W4229046517 @default.
- W4294617904 hasRelatedWork W4285554825 @default.
- W4294617904 hasRelatedWork W4294617904 @default.
- W4294617904 hasRelatedWork W4382138033 @default.
- W4294617904 hasVolume "13" @default.
- W4294617904 isParatext "false" @default.
- W4294617904 isRetracted "false" @default.
- W4294617904 workType "article" @default.