FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4294647171> ?p ?o ?g. }

• W4294647171 abstract "Abstract Background Recruitment for randomised controlled trials in palliative care can be challenging; disease progression and terminal illness underpin high rates of attrition. Research into participant decision-making in medicinal cannabis randomised controlled trials (RCTs) is very limited. Nesting qualitative sub-studies within RCTs can identify further challenges to participation, informing revisions to study designs and recruitment practices. This paper reports on findings from a qualitative sub-study supporting RCTs of medicinal cannabis for symptom burden relief in patients with advanced cancer in one Australian city. Methods Semi-structured qualitative interviews were conducted with 48 patients with advanced cancer, eligible to participate in a medicinal cannabis RCT ( n =28 who consented to participate in an RCT; n =20 who declined). An iterative and abductive approach to thematic analysis and data collection fostered exploration of barriers and enablers to participation. Results Key enablers included participants’ enthusiasm and expectations of medicinal cannabis as beneficial (to themselves and future patients) for symptom management, especially after exhausting currently approved options, and a safer alternative to opioids. Some believed medicinal cannabis to have anti-cancer effects. Barriers to participation were the logistical challenges of participating (especially due to driving restrictions and fatigue), reluctance to interfere with an existing care plan, cost, and concerns about receiving the placebo and the uncertainty of the benefit. Some declined due to concerns about side-effects or a desire to continue accessing cannabis independent of the study. Conclusions The findings support revisions to subsequent medicinal cannabis RCT study designs, namely, omitting a requirement that participants attend weekly hospital appointments. These findings highlight the value of embedding qualitative sub-studies into RCTs. While some challenges to RCT recruitment are universal, others are context (population, intervention, location) specific. A barrier to participation found in research conducted elsewhere—stigma—was not identified in the current study. Thus, findings have important implications for those undertaking RCTs in the rapidly developing context of medical cannabis." @default.
• W4294647171 created "2022-09-05" @default.
• W4294647171 creator A5028410428 @default.
• W4294647171 creator A5061828018 @default.
• W4294647171 creator A5067036759 @default.
• W4294647171 creator A5069828492 @default.
• W4294647171 creator A5079963699 @default.
• W4294647171 creator A5084042135 @default.
• W4294647171 date "2022-09-05" @default.
• W4294647171 modified "2023-10-18" @default.
• W4294647171 title "Using a qualitative sub-study to inform the design and delivery of randomised controlled trials on medicinal cannabis for symptom relief in patients with advanced cancer" @default.
• W4294647171 cites W1527321127 @default.
• W4294647171 cites W1587671491 @default.
• W4294647171 cites W1903420632 @default.
• W4294647171 cites W1946406407 @default.
• W4294647171 cites W1955053714 @default.
• W4294647171 cites W1992565690 @default.
• W4294647171 cites W1998564591 @default.
• W4294647171 cites W2040900627 @default.
• W4294647171 cites W2044522845 @default.
• W4294647171 cites W2057039980 @default.
• W4294647171 cites W2057209931 @default.
• W4294647171 cites W2064370814 @default.
• W4294647171 cites W2101536956 @default.
• W4294647171 cites W2121847763 @default.
• W4294647171 cites W2121893868 @default.
• W4294647171 cites W2122180275 @default.
• W4294647171 cites W2123009097 @default.
• W4294647171 cites W2129115519 @default.
• W4294647171 cites W2129915352 @default.
• W4294647171 cites W2133124363 @default.
• W4294647171 cites W2142323755 @default.
• W4294647171 cites W2142995931 @default.
• W4294647171 cites W2159418632 @default.
• W4294647171 cites W2170108681 @default.
• W4294647171 cites W2173461993 @default.
• W4294647171 cites W2415220657 @default.
• W4294647171 cites W2417585809 @default.
• W4294647171 cites W2493763979 @default.
• W4294647171 cites W2511607249 @default.
• W4294647171 cites W2516017084 @default.
• W4294647171 cites W2522293097 @default.
• W4294647171 cites W2620089260 @default.
• W4294647171 cites W2791111785 @default.
• W4294647171 cites W2794337332 @default.
• W4294647171 cites W2799565684 @default.
• W4294647171 cites W2809664931 @default.
• W4294647171 cites W2810334534 @default.
• W4294647171 cites W2864196379 @default.
• W4294647171 cites W2885735634 @default.
• W4294647171 cites W2886609026 @default.
• W4294647171 cites W2924464232 @default.
• W4294647171 cites W2944495881 @default.
• W4294647171 cites W2946275214 @default.
• W4294647171 cites W2948424461 @default.
• W4294647171 cites W2950504429 @default.
• W4294647171 cites W2964848022 @default.
• W4294647171 cites W2989621484 @default.
• W4294647171 cites W2992312534 @default.
• W4294647171 cites W2993832371 @default.
• W4294647171 cites W3003059730 @default.
• W4294647171 cites W3006497828 @default.
• W4294647171 cites W3013594891 @default.
• W4294647171 cites W3015119188 @default.
• W4294647171 cites W3016199036 @default.
• W4294647171 cites W3033556781 @default.
• W4294647171 cites W3040679668 @default.
• W4294647171 cites W3047048255 @default.
• W4294647171 cites W3091199432 @default.
• W4294647171 cites W3096819560 @default.
• W4294647171 cites W3105054372 @default.
• W4294647171 cites W3107033767 @default.
• W4294647171 cites W3112147116 @default.
• W4294647171 cites W3124827536 @default.
• W4294647171 cites W3126310049 @default.
• W4294647171 cites W3134587622 @default.
• W4294647171 cites W3158641451 @default.
• W4294647171 cites W3161100883 @default.
• W4294647171 cites W3171041369 @default.
• W4294647171 cites W3206411797 @default.
• W4294647171 cites W4234529789 @default.
• W4294647171 doi "https://doi.org/10.1186/s13063-022-06691-1" @default.
• W4294647171 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36064621" @default.
• W4294647171 hasPublicationYear "2022" @default.
• W4294647171 type Work @default.
• W4294647171 citedByCount "1" @default.
• W4294647171 countsByYear W42946471712022 @default.
• W4294647171 crossrefType "journal-article" @default.
• W4294647171 hasAuthorship W4294647171A5028410428 @default.
• W4294647171 hasAuthorship W4294647171A5061828018 @default.
• W4294647171 hasAuthorship W4294647171A5067036759 @default.
• W4294647171 hasAuthorship W4294647171A5069828492 @default.
• W4294647171 hasAuthorship W4294647171A5079963699 @default.
• W4294647171 hasAuthorship W4294647171A5084042135 @default.
• W4294647171 hasBestOaLocation W42946471711 @default.
• W4294647171 hasConcept C118552586 @default.
• W4294647171 hasConcept C141071460 @default.
• W4294647171 hasConcept C142724271 @default.
• W4294647171 hasConcept C144024400 @default.
• W4294647171 hasConcept C159110408 @default.

• next