Matches in SemOpenAlex for { <https://semopenalex.org/work/W4294716447> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W4294716447 abstract "Abstract Background Exacerbations in chronic obstructive pulmonary disease (COPD) are major contributors to worsening lung function, impaired quality of life, emergency healthcare use, and COPD-related mortality. COPD exacerbations are heterogeneous in terms of airway inflammation and etiology. Objectives To assess the relation between blood and sputum eosinophils and COPD exacerbation. Subjects and methods Prospective cohort study, conducted on 100 COPD patients presented in outpatient clinic. All patients were subjected to medical history including: occupational history, smoking history, comorbidity, number of exacerbations in last year and their degree, history of admission in the last year and treatment taken for COPD. Modified Medical Research Council scale of dyspnea, peak expiratory flow rate, oxygen saturation using pulse oximetry. Complete blood count with differential eosinophilic count. Sputum sample differential cell count was done. Results The eosinophil level in blood before and after treatment showed a significant positive correlation with the number of hospital admission in the last year ( r = 0.29; P = 0.003 and r = 0.3; P = 0.002, respectively). Regarding the eosinophil level either in blood or in sputum, it showed significant statistical elevation in patients not using steroid treatment in comparison to patients who used systemic or inhaled steroid treatments ( P < 0.001 and 0.004, respectively). Conclusion Blood eosinophil count can be used as a severity marker of COPD exacerbations. The eosinophil levels, either in blood or sputum, were significantly correlated with the degree of exacerbation. Sputum eosinophilia can also predict the risk of hospitalization. In addition, blood eosinophil count can direct the use of oral corticosteroids in exacerbation." @default.
- W4294716447 created "2022-09-06" @default.
- W4294716447 creator A5018022787 @default.
- W4294716447 creator A5050214085 @default.
- W4294716447 creator A5087951108 @default.
- W4294716447 date "2022-09-04" @default.
- W4294716447 modified "2023-09-25" @default.
- W4294716447 title "Blood and sputum eosinophilia in COPD exacerbation" @default.
- W4294716447 cites W1760281680 @default.
- W4294716447 cites W2110483570 @default.
- W4294716447 cites W2113430717 @default.
- W4294716447 cites W2137890862 @default.
- W4294716447 cites W2192441381 @default.
- W4294716447 cites W2269941404 @default.
- W4294716447 cites W2336296529 @default.
- W4294716447 cites W2343634874 @default.
- W4294716447 cites W2515655475 @default.
- W4294716447 cites W2530594118 @default.
- W4294716447 cites W2613974366 @default.
- W4294716447 cites W2770113020 @default.
- W4294716447 cites W2783705291 @default.
- W4294716447 cites W2784255361 @default.
- W4294716447 cites W2793035822 @default.
- W4294716447 cites W2802035483 @default.
- W4294716447 cites W2889531427 @default.
- W4294716447 cites W2893748468 @default.
- W4294716447 cites W2973884043 @default.
- W4294716447 cites W2994650557 @default.
- W4294716447 cites W4210349548 @default.
- W4294716447 doi "https://doi.org/10.1186/s43168-022-00151-9" @default.
- W4294716447 hasPublicationYear "2022" @default.
- W4294716447 type Work @default.
- W4294716447 citedByCount "1" @default.
- W4294716447 countsByYear W42947164472022 @default.
- W4294716447 crossrefType "journal-article" @default.
- W4294716447 hasAuthorship W4294716447A5018022787 @default.
- W4294716447 hasAuthorship W4294716447A5050214085 @default.
- W4294716447 hasAuthorship W4294716447A5087951108 @default.
- W4294716447 hasBestOaLocation W42947164471 @default.
- W4294716447 hasConcept C126322002 @default.
- W4294716447 hasConcept C142724271 @default.
- W4294716447 hasConcept C2776042228 @default.
- W4294716447 hasConcept C2776301714 @default.
- W4294716447 hasConcept C2776780178 @default.
- W4294716447 hasConcept C2777014857 @default.
- W4294716447 hasConcept C2777037409 @default.
- W4294716447 hasConcept C2777129736 @default.
- W4294716447 hasConcept C2781069245 @default.
- W4294716447 hasConcept C3020110884 @default.
- W4294716447 hasConcept C71924100 @default.
- W4294716447 hasConceptScore W4294716447C126322002 @default.
- W4294716447 hasConceptScore W4294716447C142724271 @default.
- W4294716447 hasConceptScore W4294716447C2776042228 @default.
- W4294716447 hasConceptScore W4294716447C2776301714 @default.
- W4294716447 hasConceptScore W4294716447C2776780178 @default.
- W4294716447 hasConceptScore W4294716447C2777014857 @default.
- W4294716447 hasConceptScore W4294716447C2777037409 @default.
- W4294716447 hasConceptScore W4294716447C2777129736 @default.
- W4294716447 hasConceptScore W4294716447C2781069245 @default.
- W4294716447 hasConceptScore W4294716447C3020110884 @default.
- W4294716447 hasConceptScore W4294716447C71924100 @default.
- W4294716447 hasIssue "1" @default.
- W4294716447 hasLocation W42947164471 @default.
- W4294716447 hasLocation W42947164472 @default.
- W4294716447 hasOpenAccess W4294716447 @default.
- W4294716447 hasPrimaryLocation W42947164471 @default.
- W4294716447 hasRelatedWork W1907412251 @default.
- W4294716447 hasRelatedWork W1994856695 @default.
- W4294716447 hasRelatedWork W2099273877 @default.
- W4294716447 hasRelatedWork W2371957641 @default.
- W4294716447 hasRelatedWork W2409027059 @default.
- W4294716447 hasRelatedWork W3211943667 @default.
- W4294716447 hasRelatedWork W4306810337 @default.
- W4294716447 hasRelatedWork W67955181 @default.
- W4294716447 hasRelatedWork W2160990225 @default.
- W4294716447 hasRelatedWork W2189258505 @default.
- W4294716447 hasVolume "16" @default.
- W4294716447 isParatext "false" @default.
- W4294716447 isRetracted "false" @default.
- W4294716447 workType "article" @default.