Matches in SemOpenAlex for { <https://semopenalex.org/work/W4294770817> ?p ?o ?g. }
- W4294770817 abstract "Fluorination of carbanions is pivotal for the synthesis of fluorinated compounds, but the current N-F fluorinating agents have significant drawbacks due to many reactive locations that surround the reactive N−F site. By developing a sterically hindered N-fluorosulfonamide reagent, namely N-fluoro-N-(tert-butyl)-tert-butanesulfonamide (NFBB), we discovered a conceptually novel base-catalyzed, self-sustaining fluorination of active methylene compounds and achieved the high-yielding fluorination of the hitherto difficult highly basic (hetero)aryl and alkenyl lithium species. In the former, the mild and high yield fluorination of active methylene compounds exhibited wide functional group tolerance and its novel catalytic fluorination-deprotonation cycle mechanism was demonstrated by deuterium-tracing experiments. In the latter, NFBB reacted with a variety of highly basic (hetero)aryl and alkenyl lithium species to provide the desired fluoro (hetero)arenes and alkenes in unprecedented high or quantitative yields." @default.
- W4294770817 created "2022-09-06" @default.
- W4294770817 creator A5002824454 @default.
- W4294770817 creator A5061002470 @default.
- W4294770817 creator A5090395283 @default.
- W4294770817 date "2022-09-26" @default.
- W4294770817 modified "2023-09-24" @default.
- W4294770817 title "Self‐Sustaining Fluorination of Active Methylene Compounds and High‐Yielding Fluorination of Highly Basic Aryl and Alkenyl Lithium Species with a Sterically Hindered <i>N</i> ‐Fluorosulfonamide Reagent" @default.
- W4294770817 cites W1520678632 @default.
- W4294770817 cites W1959392239 @default.
- W4294770817 cites W1965582322 @default.
- W4294770817 cites W1970901533 @default.
- W4294770817 cites W1973911517 @default.
- W4294770817 cites W1983357954 @default.
- W4294770817 cites W1983583125 @default.
- W4294770817 cites W1992464455 @default.
- W4294770817 cites W1993195042 @default.
- W4294770817 cites W1997570858 @default.
- W4294770817 cites W2002572540 @default.
- W4294770817 cites W2010179367 @default.
- W4294770817 cites W2014259612 @default.
- W4294770817 cites W2032175435 @default.
- W4294770817 cites W2043402406 @default.
- W4294770817 cites W2045807329 @default.
- W4294770817 cites W2048215918 @default.
- W4294770817 cites W2049190709 @default.
- W4294770817 cites W2063086356 @default.
- W4294770817 cites W2064675039 @default.
- W4294770817 cites W2065983055 @default.
- W4294770817 cites W2074254364 @default.
- W4294770817 cites W2078984090 @default.
- W4294770817 cites W2081613332 @default.
- W4294770817 cites W2094065729 @default.
- W4294770817 cites W2098082802 @default.
- W4294770817 cites W2098832660 @default.
- W4294770817 cites W2141471401 @default.
- W4294770817 cites W2156381949 @default.
- W4294770817 cites W2162139856 @default.
- W4294770817 cites W2164595616 @default.
- W4294770817 cites W2170687270 @default.
- W4294770817 cites W2178640639 @default.
- W4294770817 cites W2316271561 @default.
- W4294770817 cites W2334844698 @default.
- W4294770817 cites W2606330829 @default.
- W4294770817 cites W2610341741 @default.
- W4294770817 cites W2785609333 @default.
- W4294770817 cites W2793226189 @default.
- W4294770817 cites W2807110388 @default.
- W4294770817 cites W2899819371 @default.
- W4294770817 cites W2901404284 @default.
- W4294770817 cites W2937748569 @default.
- W4294770817 cites W2945972170 @default.
- W4294770817 cites W2949305339 @default.
- W4294770817 cites W2950435496 @default.
- W4294770817 cites W2951084186 @default.
- W4294770817 cites W2952275747 @default.
- W4294770817 cites W2952881182 @default.
- W4294770817 cites W2983431804 @default.
- W4294770817 cites W3011727358 @default.
- W4294770817 cites W3019266968 @default.
- W4294770817 cites W3057402443 @default.
- W4294770817 cites W3081373768 @default.
- W4294770817 cites W3186926547 @default.
- W4294770817 cites W4291208076 @default.
- W4294770817 doi "https://doi.org/10.1002/ange.202211688" @default.
- W4294770817 hasPublicationYear "2022" @default.
- W4294770817 type Work @default.
- W4294770817 citedByCount "0" @default.
- W4294770817 crossrefType "journal-article" @default.
- W4294770817 hasAuthorship W4294770817A5002824454 @default.
- W4294770817 hasAuthorship W4294770817A5061002470 @default.
- W4294770817 hasAuthorship W4294770817A5090395283 @default.
- W4294770817 hasConcept C118629725 @default.
- W4294770817 hasConcept C134018914 @default.
- W4294770817 hasConcept C145148216 @default.
- W4294770817 hasConcept C155647269 @default.
- W4294770817 hasConcept C161790260 @default.
- W4294770817 hasConcept C178790620 @default.
- W4294770817 hasConcept C185592680 @default.
- W4294770817 hasConcept C201194858 @default.
- W4294770817 hasConcept C21951064 @default.
- W4294770817 hasConcept C2777454769 @default.
- W4294770817 hasConcept C2778541603 @default.
- W4294770817 hasConcept C2780263894 @default.
- W4294770817 hasConcept C2781076698 @default.
- W4294770817 hasConcept C40875361 @default.
- W4294770817 hasConcept C506198293 @default.
- W4294770817 hasConcept C71924100 @default.
- W4294770817 hasConcept C82894169 @default.
- W4294770817 hasConceptScore W4294770817C118629725 @default.
- W4294770817 hasConceptScore W4294770817C134018914 @default.
- W4294770817 hasConceptScore W4294770817C145148216 @default.
- W4294770817 hasConceptScore W4294770817C155647269 @default.
- W4294770817 hasConceptScore W4294770817C161790260 @default.
- W4294770817 hasConceptScore W4294770817C178790620 @default.
- W4294770817 hasConceptScore W4294770817C185592680 @default.
- W4294770817 hasConceptScore W4294770817C201194858 @default.
- W4294770817 hasConceptScore W4294770817C21951064 @default.
- W4294770817 hasConceptScore W4294770817C2777454769 @default.
- W4294770817 hasConceptScore W4294770817C2778541603 @default.